Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Laura Scalambra"'
Autor:
Francesca Ruzzi, Chiara Cappello, Maria Sofia Semprini, Laura Scalambra, Stefania Angelicola, Olga Maria Pittino, Lorena Landuzzi, Arianna Palladini, Patrizia Nanni, Pier-Luigi Lollini
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-10 (2024)
Abstract Lipid rafts are dynamic microdomains enriched with cholesterol and sphingolipids that play critical roles in cellular processes by organizing and concentrating specific proteins involved in signal transduction. The interplay between lipid ra
Externí odkaz:
https://doaj.org/article/0f01f19499ac4787836667014821c1c1
Autor:
Veronica Giusti, Francesca Ruzzi, Lorena Landuzzi, Marianna L. Ianzano, Roberta Laranga, Elena Nironi, Laura Scalambra, Giordano Nicoletti, Carla De Giovanni, Martina Olivero, Maddalena Arigoni, Raffaele Calogero, Patrizia Nanni, Arianna Palladini, Pier-Luigi Lollini
Publikováno v:
Oncogenesis, Vol 10, Iss 11, Pp 1-12 (2021)
Abstract HER2-positive breast cancers may lose HER2 expression in recurrences and metastases. In this work, we studied cell lines derived from two transgenic mammary tumors driven by human HER2 that showed different dynamics of HER2 status. MamBo89HE
Externí odkaz:
https://doaj.org/article/b560bd2ffc044642b16dd92b9b06a0fa
Autor:
Francesca Ruzzi, Maria Sofia Semprini, Laura Scalambra, Arianna Palladini, Stefania Angelicola, Chiara Cappello, Olga Maria Pittino, Patrizia Nanni, Pier-Luigi Lollini
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 16, p 12963 (2023)
Cancer vaccines are increasingly being studied as a possible strategy to prevent and treat cancers. While several prophylactic vaccines for virus-caused cancers are approved and efficiently used worldwide, the development of therapeutic cancer vaccin
Externí odkaz:
https://doaj.org/article/8ded555a69794ee0b5e08c117ab222f2
Autor:
Lorena Landuzzi, Arianna Palladini, Claudio Ceccarelli, Sofia Asioli, Giordano Nicoletti, Veronica Giusti, Francesca Ruzzi, Marianna L. Ianzano, Laura Scalambra, Roberta Laranga, Tania Balboni, Maddalena Arigoni, Martina Olivero, Raffaele A. Calogero, Carla De Giovanni, Massimiliano Dall’Ora, Enrico Di Oto, Donatella Santini, Maria Pia Foschini, Maria Cristina Cucchi, Simone Zanotti, Mario Taffurelli, Patrizia Nanni, Pier-Luigi Lollini
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract We established patient-derived xenografts (PDX) from human primary breast cancers and studied whether stability or progressive events occurred during long-term in vivo passages (up to 4 years) in severely immunodeficient mice. While most PDX
Externí odkaz:
https://doaj.org/article/59a0895a37d34757859e7e9b853a7ad6
Autor:
Francesca Ruzzi, Arianna Palladini, Stine Clemmensen, Anette Strøbæk, Nicolaas Buijs, Tanja Domeyer, Jerzy Dorosz, Vladislav Soroka, Dagmara Grzadziela, Christina Jo Rasmussen, Ida Busch Nielsen, Max Soegaard, Maria Sofia Semprini, Laura Scalambra, Stefania Angelicola, Lorena Landuzzi, Pier-Luigi Lollini, Mette Thorn
Publikováno v:
Biomedicines, Vol 10, Iss 10, p 2654 (2022)
Vaccines are a promising therapeutic alternative to monoclonal antibodies against HER-2+ breast cancer. We present the preclinical activity of an ES2B-C001, a VLP-based vaccine being developed for human breast cancer therapy. FVB mice challenged with
Externí odkaz:
https://doaj.org/article/86f3d463db8d46898126b8d04acfafb3
Autor:
Francesca Ruzzi, Stefania Angelicola, Lorena Landuzzi, Elena Nironi, Maria Sofia Semprini, Laura Scalambra, Annalisa Altimari, Elisa Gruppioni, Michelangelo Fiorentino, Francesca Giunchi, Manuela Ferracin, Annalisa Astolfi, Valentina Indio, Andrea Ardizzoni, Francesco Gelsomino, Patrizia Nanni, Pier-Luigi Lollini, Arianna Palladini
Publikováno v:
Translational Lung Cancer Research. 11:2216-2229
(NSCLCs). Several tyrosine kinase inhibitors (TKIs) have shown high efficacy in patients whose tumors harbour a ROS1 fusion. However, the limited availability of preclinical models of ROS1-positive NSCLC hinders the discovery of new drugs and the und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f67823ef083b272c51fc020d1542e6cd
https://doi.org/10.21037/tlcr-22-163
https://doi.org/10.21037/tlcr-22-163
Autor:
Francesca Ruzzi, Arianna Palladini, Stine Clemmensen, Annette Strobaek, Nicolaas Buijs, Tanja Domeyer, Jerzy Dorosz, Vladislav Soroka, Dagmara Grzadziela, Christina Jo Rasmussen, Ida Busch Nielsen, Max Soegaard, Maria Sofia Semprini, Laura Scalambra, Stefania Angelicola, Lorena Landuzzi, Pier-Luigi Lollini, Mette Thorn
Publikováno v:
Cancer Research. 83:687-687
ES2B-C001 is a virus-like particle (VLP) vaccine against human HER-2, developed for the therapy of breast cancer. We show here that ES2B-C001 effectively inhibits mammary carcinoma growth and metastasis in a transgenic mouse model expressing activate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9cea3a520ba5f9c421dc0ba2a9691002
https://doi.org/10.1158/1538-7445.am2023-687
https://doi.org/10.1158/1538-7445.am2023-687
Autor:
Tania Balboni, Claudio Ceccarelli, Maria Pia Foschini, Mario Taffurelli, Veronica Giusti, Maria C. Cucchi, Francesca Ruzzi, Roberta Laranga, Laura Scalambra, Pier Luigi Lollini, Carla De Giovanni, Arianna Palladini, Raffaele Calogero, Simone Zanotti, Marianna L. Ianzano, Enrico Di Oto, Patrizia Nanni, Maddalena Arigoni, Martina Olivero, Giordano Nicoletti, Lorena Landuzzi, Massimiliano Dall'Ora, Donatella Santini, Sofia Asioli
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports
Scientific Reports
We established patient-derived xenografts (PDX) from human primary breast cancers and studied whether stability or progressive events occurred during long-term in vivo passages (up to 4 years) in severely immunodeficient mice. While most PDX showed s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6afbede2c461e88153a2425f4994655d
https://doaj.org/article/59a0895a37d34757859e7e9b853a7ad6
https://doaj.org/article/59a0895a37d34757859e7e9b853a7ad6
Autor:
Pier Luigi Lollini, Giordano Nicoletti, Carla De Giovanni, Patrizia Nanni, Francesca Ruzzi, Lorena Landuzzi, Elena Nironi, Marianna L. Ianzano, Laura Scalambra, Raffaele Calogero, Maddalena Arigoni, M. Olivero, Roberta Laranga, Veronica Giusti, Arianna Palladini
Publikováno v:
Oncogenesis, Vol 10, Iss 11, Pp 1-12 (2021)
Oncogenesis
Oncogenesis
HER2-positive breast cancers may lose HER2 expression in recurrences and metastases. In this work, we studied cell lines derived from two transgenic mammary tumors driven by human HER2 that showed different dynamics of HER2 status. MamBo89HER2stable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e10666c8b5a04758676e3b30e3dad8c
https://doi.org/10.1038/s41389-021-00360-9
https://doi.org/10.1038/s41389-021-00360-9
Autor:
Arianna Palladini, Pier Luigi Lollini, Laura Scalambra, Francesco Gelsomino, Lorena Landuzzi, Stefania Angelicola, Andrea Ardizzoni, Patrizia Nanni, Francesca Ruzzi
Publikováno v:
Cancers
Cancers, Vol 13, Iss 309, p 309 (2021)
Cancers, Vol 13, Iss 309, p 309 (2021)
Simple Summary Hyperprogressive disease (HPD) is a pattern of paradoxical tumor progression that has been reported in patients treated with immune checkpoint inhibitors (ICIs). Although a large number of studies have investigated HPD and several asso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83b42a4d104a569da92459b3cbc77f71
https://doi.org/10.3390/cancers13020309
https://doi.org/10.3390/cancers13020309