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pro vyhledávání: '"Laura Sayegh"'
Publikováno v:
Public Health Genomics
Background: Natural history (NH) studies, using observational methods, are common in rare and orphan diseases (80% of which have a genetic component). There is profound interest in identifying genetic mutations driving these diseases in these studies
Publikováno v:
Drugs in R&D
Background Rapidly disintegrating or ‘fast-melt’ oral formulations have been developed recently to facilitate drug intake among patients. Even though these formulations have helped to improve therapy adherence, some of their limitations include:
Autor:
Laura Sayegh, Mostafa Zamanian, Chuanzhe Song, Fouad El-Shehabi, Tim A. Day, Paula Ribeiro, Debra J. Woods, Michael J. Kimber
Publikováno v:
International Journal for Parasitology. 39:1215-1222
Acetylcholine (ACh) is a neurotransmitter/neuromodulator in the nematode nervous system and induces its effects through interaction with both ligand-gated ion channels (LGICs) and G protein-coupled receptors (GPCRs). The structure, pharmacology and p