Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Laura Sartori Assunção"'
Autor:
Débora Mocellin, Letícia de Oliveira Souza Bratti, Adny Henrique Silva, Laura Sartori Assunção, Iara Fabricia Kretzer, Fabíola Branco Filippin-Monteiro
Publikováno v:
Brazilian Journal of Pharmaceutical Sciences, Vol 58 (2022)
Abstract Here we examined whether serum from obese patients could create a growth-enhancing microenvironment that alters gene expression in BRAF- and NRAS-mutated melanoma cell lines. SK-Mel-28 (BRAF-mutated) and Sk-Mel-147 (NRAS-mutated) cells were
Externí odkaz:
https://doaj.org/article/d8ea397064d94b36b3651fc52f9090b8
Autor:
Adny Henrique Silva, Laura Sartori Assunção, Fabíola Branco Filippin-Monteiro, Misael Ferreira, Tânia Beatriz Creczynski-Pasa, Marcus M. Sá
Publikováno v:
European Journal of Medicinal Chemistry. 129:151-158
A series of 28 aryl- and alkyl-substituted isothiouronium salts were readily synthesized in high yields through the reaction of allylic bromides with thiourea, N-monosubstituted thioureas or thiosemicarbazide. The S-allylic isothiouronium salts subst
Autor:
Juliana Inaba, Daniela P. Gouvêa, Adailton J. Bortoluzzi, Laura Sartori Assunção, Marcus M. Sá, Laiéli S. Munaretto, Misael Ferreira, Tânia Beatriz Creczynski-Pasa
Publikováno v:
Tetrahedron. 76:131231
A convenient route for the synthesis of isothiosemicarbazones and 2-hydrazono-1,3-thiazin-4-ones through a multicomponent reaction featuring allylic bromides, carbonyl compounds and thiosemicarbazides is described. The transformations proceed under m
Autor:
Leônidas João de Mello Junior, Jelver Alexander Sierra Restrepo, Adny Henrique Silva, Iara Fabricia Kretzer, Misael Ferreira, Tânia Beatriz Creczynski-Pasa, Laura Sartori Assunção, Eliana de Medeiros Oliveira, Marcus M. Sá
Publikováno v:
Biochimica et biophysica acta. General subjects. 1863(9)
In a previous study, we described a series of 28 aryl- and alkyl-substituted isothiouronium salts with antitumor activity and selectivity toward a leukemia cell line. Among the synthesized compounds, methyl (Z)-2-(isothioureidomethyl)-2-pentenoate hy
Autor:
Marcus M. Sá, Laura Sartori Assunção, Fabíola Branco Filippin-Monteiro, Misael Ferreira, Tânia Beatriz Creczynski-Pasa
Publikováno v:
European Journal of Medicinal Chemistry. 70:411-418
2-Amino-1,3-thiazin-4-ones were subjected to acetylation followed by mild acid hydrolysis to give compounds containing the 1,3-thiazine-2,4-dione core. The potential of these S,N-containing heterocycles as antitumor agents against human cancer cell l
Autor:
Laura Sartori Assunção, Marjorie G. P. Marin, Misael Ferreira, Marcus M. Sá, Tânia Beatriz Creczynski-Pasa, Michele Patrícia Rode, Iara Fabricia Kretzer
Publikováno v:
Clinical Cancer Research. 24:B67-B67
Skin cancer is the most common type of cancer in Brazil and accounts for 25% of all registered cases. Within this group, melanoma is considered the most severe and aggressive due to the possibility of metastasis. Melanoma is responsible for 79% of sk
Autor:
Laura Sartori Assunção, Misael Ferreira, Marcus M. Sá, Fabíola Branco Filippin-Monteiro, Tânia Beatriz Creczynski-Pasa
Publikováno v:
ChemInform. 45
2-Amino-1,3-thiazin-4-ones were subjected to acetylation followed by mild acid hydrolysis to give compounds containing the 1,3-thiazine-2,4-dione core. The potential of these S,N-containing heterocycles as antitumor agents against human cancer cell l
Autor:
Rosendo A. Yunes, Clarissa A.S. de Cordova, Bruno Mattei, Alessandra Mascarello, Claudriana Locatelli, Laura Sartori Assunção, Ricardo José Nunes, Evelyn Winter, Tânia Beatriz Creczynski-Pasa
Publikováno v:
Toxicology in Vitro. (8):2025-2034
This study investigated the mechanism of cytotoxicity of octyl (G8) and dodecyl (G12) gallates in a murine melanoma cell line (B16F10). For this purpose, several methods to measure cell viability were used to determine if the cytotoxicity induced by