Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Laura Santos Sanchez"'
Autor:
Raúl R. Rodrigues-Diez, Antonio Tejera-Muñoz, Macarena Orejudo, Laura Marquez-Exposito, Laura Santos-Sanchez, Sandra Rayego-Mateos, Elena Cantero-Navarro, Lucia Tejedor-Santamaria, Vanessa Marchant, Alberto Ortiz, Jesús Egido, Sergio Mezzano, Rafael Selgas, Juan F. Navarro-González, Jose M. Valdivielso, Carolina Lavoz, Marta Ruiz-Ortega
Publikováno v:
Nefrología (English Edition), Vol 41, Iss 3, Pp 244-257 (2021)
Interleukin-17A (IL-17A) is a proinflammatory cytokine produced by cells of the immune system, predominantly Th17 and γδ lymphocytes. In this paper, we review the role of IL-17A in the pathogenesis of hypertension and in target organ damage. Precli
Externí odkaz:
https://doaj.org/article/83149afb48cd47049f3cfeb094a5b112
Autor:
Elena Cantero-Navarro, Sandra Rayego-Mateos, Macarena Orejudo, Lucía Tejedor-Santamaria, Antonio Tejera-Muñoz, Ana Belén Sanz, Laura Marquez-Exposito, Vanessa Marchant, Laura Santos-Sanchez, Jesús Egido, Alberto Ortiz, Teresa Bellon, Raúl R. Rodrigues-Diez, Marta Ruiz-Ortega
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Inflammation is a key characteristic of kidney disease, but this immune response is two-faced. In the acute phase of kidney injury, there is an activation of the immune cells to fight against the insult, contributing to kidney repair and regeneration
Externí odkaz:
https://doaj.org/article/eec648e0a92a47858d82fa4128d29513
Autor:
Laura Marquez-Exposito, Lucia Tejedor-Santamaria, Laura Santos-Sanchez, Floris A. Valentijn, Elena Cantero-Navarro, Sandra Rayego-Mateos, Raul R. Rodrigues-Diez, Antonio Tejera-Muñoz, Vanessa Marchant, Ana B. Sanz, Alberto Ortiz, Roel Goldschmeding, Marta Ruiz-Ortega
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Acute kidney injury (AKI) is more frequent in elderly patients. Mechanisms contributing to AKI (tubular cell death, inflammatory cell infiltration, impaired mitochondrial function, and prolonged cell-cycle arrest) have been linked to cellular senesce
Externí odkaz:
https://doaj.org/article/eb14e45a559945cd9ceb2ba0fcda3ed8
Autor:
Vanessa Marchant, Antonio Tejera-Muñoz, Laura Marquez-Expósito, Sandra Rayego-Mateos, Raul R. Rodrigues-Diez, Lucia Tejedor, Laura Santos-Sanchez, Jesús Egido, Alberto Ortiz, Jose M. Valdivielso, Donald J. Fraser, Manuel López-Cabrera, Rafael Selgas, Marta Ruiz-Ortega
Publikováno v:
Biomolecules, Vol 10, Iss 10, p 1361 (2020)
Chronic kidney disease (CKD) is a health problem reaching epidemic proportions. There is no cure for CKD, and patients may progress to end-stage renal disease (ESRD). Peritoneal dialysis (PD) is a current replacement therapy option for ESRD patients
Externí odkaz:
https://doaj.org/article/c203dffe88374e5ca1c163b53c65b8ba
Autor:
Antonio Tejera-Muñoz, Carolina Lavoz, Elena Cantero-Navarro, Sergio Mezzano, Alberto Ortiz, Raúl R. Rodrigues-Diez, Sandra Rayego-Mateos, Laura Santos-Sanchez, Jesús Egido, Vanessa Marchant, Jose M. Valdivielso, Rafael Selgas, Marta Ruiz-Ortega, Lucia Tejedor-Santamaria, Laura Marquez-Exposito, Macarena Orejudo, Juan F. Navarro-González
Publikováno v:
Nefrología (English Edition), Vol 41, Iss 3, Pp 244-257 (2021)
Interleukin-17A (IL-17A) is a proinflammatory cytokine produced by cells of the immunesystem, predominantly Th17 and lymphocytes. In this paper, we review the role of IL-17A in the pathogenesis of hypertension and in target organ damage. Preclinical
Autor:
Raul Rodrigues Diez, Laura Marquez-Exposito, Sandra Rayego-Mateos, Laura Santos-Sanchez, Roel Goldschmeding, Lucia Tejedor, Elena Cantero-Navarro, Alberto Ortiz, Antonio Tejera-Muñoz, Vanessa Marchant, Marta Ruiz-Ortega, Floris A. Valentijn, Ana Belen Sanz
Publikováno v:
Nephrology Dialysis Transplantation. 36
Background and Aims Acute kidney injury (AKI) is associated with elevated mortality and morbidity presenting higher frequency in aged patients. Different mechanisms are activated in AKI, including tubular epithelial cell death (apoptosis and regulate
Autor:
Laura, Marquez-Exposito, Elena, Cantero-Navarro, Raúl, R Rodrigues-Diez, Macarena, Orejudo, Antonio, Tejera-Muñoz, Lucia, Tejedor, Sandra, Rayego-Mateos, Javier, Rández-Carbayo, Laura, Santos-Sanchez, Sergio, Mezzano, Carolina, Lavoz, Marta, Ruiz-Ortega
Publikováno v:
Advances in experimental medicine and biology. 1227
Gremlin is a member of the TGF-β superfamily that can act as a BMP antagonist, and recently, has been described as a ligand of the vascular endothelial growth factor receptor 2 (VEGFR2). Gremlin shares properties with the Notch signaling pathway. Bo
Autor:
Macarena Orejudo, Elena Cantero-Navarro, Sandra Rayego-Mateos, Javier Rández-Carbayo, Carolina Lavoz, Laura Santos-Sanchez, Sergio Mezzano, Marta Ruiz-Ortega, Lucia Tejedor, Antonio Tejera-Muñoz, Raúl R. Rodrigues-Diez, Laura Marquez-Exposito
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9783030364212
Gremlin is a member of the TGF-β superfamily that can act as a BMP antagonist, and recently, has been described as a ligand of the vascular endothelial growth factor receptor 2 (VEGFR2). Gremlin shares properties with the Notch signaling pathway. Bo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fea888cfa7416031e68dd97355c9ab4f
https://doi.org/10.1007/978-3-030-36422-9_6
https://doi.org/10.1007/978-3-030-36422-9_6
Autor:
Laura Santos-Sanchez, Sandra Rayego-Mateos, Carolina Lavoz, Marta Ruiz-Ortega, Marta Fierro-Fernández, Jorge Laborda, Laura Marquez-Exposito, Raquel Rodrigues-Díez, Santiago Lamas, Raúl R. Rodrigues-Diez, Eva Maria Blanco, Macarena Orejudo, Sergio Mezzano
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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Preclinical studies have demonstrated that activation of the NOTCH pathway plays a key role in the pathogenesis of kidney damage. There is currently no information on the role of the Delta-like homologue 1 (DLK1), a NOTCH inhibitor, in the regulation
Autor:
Macarena Orejudo, Mercedes Salaices, Jesús Egido, Raquel Rodrigues-Díez, Laura Santos-Sanchez, Antonio Tejera-Muñoz, Rafael Selgas, Raúl R. Rodrigues-Diez, Marta Ruiz-Ortega, Ana M Briones, Ana B. García-Redondo
Publikováno v:
Clinical science (London, England : 1979). 134(5)
An important link exists between hypertension and inflammation. Hypertensive patients present elevated circulating levels of proinflammatory cytokines, including interleukin-17A (IL-17A). This cytokine participates in host defense, autoimmune and chr