Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Laura Sanchez‐Burgos"'
Autor:
Laura Sanchez‐Burgos, Belén Navarro‐González, Santiago García‐Martín, Oleksandra Sirozh, Jorge Mota‐Pino, Elena Fueyo‐Marcos, Héctor Tejero, Marta Elena Antón, Matilde Murga, Fátima Al‐Shahrour, Oscar Fernandez‐Capetillo
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 9, Pp 1-18 (2022)
Abstract FBXW7 is one of the most frequently mutated tumor suppressors, deficiency of which has been associated with resistance to some anticancer therapies. Through bioinformatics and genome‐wide CRISPR screens, we here reveal that FBXW7 deficienc
Externí odkaz:
https://doaj.org/article/256932fb4a3044ed836a66ac7c89974f
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract The ongoing COVID-19 pandemic is one of the biggest health challenges of recent decades. Among the causes of mortality triggered by SARS-CoV-2 infection, the development of an inflammatory “cytokine storm” (CS) plays a determinant role.
Externí odkaz:
https://doaj.org/article/ce36e435925c419e8e5abf9ccf52422a
The identification of new therapeutic uses for compounds via computational or experimental approaches, which is widely known as drug repurposing, has the potential to develop novel therapies with pre-existing medicines, thereby reducing the time and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5e7beb89a99fd937a8e710d3a5cc8e4
https://doi.org/10.1101/2023.03.10.532084
https://doi.org/10.1101/2023.03.10.532084
Activation of the Integrated Stress Response overcomes multidrug resistance in FBXW7-deficient cells
Autor:
Laura Sanchez-Burgos, Belén Navarro-González, Santiago García-Martín, Héctor Tejero, Marta Elena Antón, Fátima Al-Shahrour, Oscar Fernandez-Capetillo
SUMMARYFBXW7 is one of the most frequently mutated tumor suppressors, the deficiency of which has been associated with resistance to some anticancer therapies. Through bioinformatic analyses and genome-wide CRISPR screens, we here reveal that FBXW7 d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f9d8d21ab72086a9bc9b31b4fa4b08c
https://doi.org/10.1101/2022.01.17.476566
https://doi.org/10.1101/2022.01.17.476566
The ongoing COVID-19 pandemic is one of the biggest health and societal challenges of the recent decades. Among the causes of mortality triggered by SARS-CoV-2 infection, the presence of an inflammatory "cytokine storm" (CS) at later stages of the di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f554caec160006d9c5b97c4423754f2
https://doi.org/10.20944/preprints202006.0087.v1
https://doi.org/10.20944/preprints202006.0087.v1