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of 159
pro vyhledávání: '"Laura SCIACCA"'
The IGF-1 receptor (IGF-1-R) belongs to the tyrosine kinase growth factor receptor family. It is structurally similar to, but distinct from, the insulin receptor, with which it shares a 70% homology. As expected, it crossreacts with insulin and, vice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cdb132b860dc77d1c02771088160b116
https://doi.org/10.1385/1-59259-071-3:485
https://doi.org/10.1385/1-59259-071-3:485
Publikováno v:
Exploration of Medicine, Vol 3, Iss 2, Pp 173-180 (2022)
Semaglutide is a glucagon-like peptide 1 receptor agonist (GLP-1 RA) molecule approved for the treatment of both type 2 diabetes (T2D) and obesity. Semaglutide has a greater impact on glycated haemoglobin (HbA1c) reduction, compared to other GLP-1 RA
Externí odkaz:
https://doaj.org/article/60e6504066ef4015a4bf79c7e5bbf3ce
Publikováno v:
Exploration of Medicine, Vol 1, Iss 4, Pp 184-204 (2020)
Diabetes and cancer are widespread worldwide and the number of subjects presenting both diseases increased over the years. The management of cancer patients having diabetes represents a challenge not only because of the complexity and heterogeneity o
Externí odkaz:
https://doaj.org/article/87977c7e4dcc419fb0b86cae8eb8c7f9
Autor:
Agostino Milluzzo, Martina Barchitta, Andrea Maugeri, Roberta Magnano San Lio, Giuliana Favara, Maria Grazia Mazzone, Laura Sciacca, Antonella Agodi
Publikováno v:
Nutrients, Vol 14, Iss 20, p 4430 (2022)
Diabetic retinopathy (DR) is a multifactorial neuro-microvascular disease, whose prevalence ranges from 25% to 60% of subjects affected by diabetes mellitus, representing the main cause of legal blindness in adults of industrialized countries. The tr
Externí odkaz:
https://doaj.org/article/e8f2ed79b28b409cb2c9b5f5d6d12d4a
Autor:
Andrea Tumminia, Nunzio M. Scalisi, Agostino Milluzzo, Giuseppe Ettore, Riccardo Vigneri, Laura Sciacca
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
BackgroundMaternal high blood glucose during pregnancy increases the risk for both maternal and fetal adverse outcomes. The mechanisms underlying the regulator effects of hyperglycemia on placental development and growth have not been fully illustrat
Externí odkaz:
https://doaj.org/article/46111aa867ad433cae0997a2fb53866e
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 19, p 10502 (2021)
Diabetic retinopathy (DR) is one of the main causes of vision loss in middle-aged economically active people. Modifiable (i.e., hyperglycaemia, hypertension, hyperlipidaemia, obesity, and cigarette smoke) and non-modifiable factors (i.e., duration of
Externí odkaz:
https://doaj.org/article/326c324d0c0b44c79c0be4a39dbfa774
Autor:
Michele Massimino, Laura Sciacca, Nunziatina Laura Parrinello, Nunzio Massimo Scalisi, Antonino Belfiore, Riccardo Vigneri, Paolo Vigneri
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 16, p 8729 (2021)
The insulin receptor (IR) presents two isoforms (IR-A and IR-B) that differ for the α-subunit C-terminal. Both isoforms are expressed in all human cells albeit in different proportions, yet their functional properties-when bound or unbound to insuli
Externí odkaz:
https://doaj.org/article/1318fbbc3dbb4074a115943c6fca542f
Autor:
Cristina Bianchi, Veronica Resi, Elisa Manicardi, Silvia Burlina, Maria Angela Sculli, Gloria Formoso, Laura Sciacca
Publikováno v:
Nutrition, Metabolism and Cardiovascular Diseases.
Autor:
Lucia Manuella, Laura Sciacca
Publikováno v:
L'Endocrinologo. 24:95-96
Autor:
Andrea Tumminia, Federica Vinciguerra, Miriam Parisi, Marco Graziano, Laura Sciacca, Roberto Baratta, Lucia Frittitta
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 12, p 2863 (2019)
Adipose tissue has been recognized as a complex organ with endocrine and metabolic roles. The excess of fat mass, as occurs during overweight and obesity states, alters the regulation of adipose tissue, contributing to the development of obesity-rela
Externí odkaz:
https://doaj.org/article/8612d71f57954bc8acaa1bc52555e2d6