Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Laura S. M. Müller"'
Autor:
Laura S. M. Müller, Benedikt G. Brink, David Horn, Lucy Glover, Vanessa Luzak, Sebastian Hutchinson, Joana Faria, T. Nicolai Siegel
Publikováno v:
Nature Microbiology
Nature microbiology
Nature microbiology
Highly selective gene expression is a key requirement for antigenic variation in several pathogens, allowing evasion of host immune responses and maintenance of persistent infections1. African trypanosomes-parasites that cause lethal diseases in huma
Autor:
Noam Kaplan, Raul O Cosentino, Jörg Vogel, Christian J. Janzen, Thomas D. Otto, Carolin Wedel, Antoine-Emmanuel Saliba, T. Nicolai Siegel, Sascha Steinbiss, Julien Guizetti, Konrad U. Förstner, Robert Sebra, Laura S. M. Müller, Panagiota Arampatzi
Publikováno v:
Nature
Nature, Epub ahead of
Nature, Epub ahead of
Many evolutionarily distant pathogenic organisms have evolved similar survival strategies to evade the immune responses of their hosts. These include antigenic variation, through which an infecting organism prevents clearance by periodically altering
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::155971f66995ef1052c9c5fd521b60a9
https://hdl.handle.net/10033/621576
https://hdl.handle.net/10033/621576
Publikováno v:
Nucleic Acids Research
Monoallelic expression within a gene family is found in pathogens exhibiting antigenic variation and in mammalian olfactory neurons. Trypanosoma brucei, a lethal parasite living in the human bloodstream, expresses variant surface glycoprotein (VSG) f