Výsledky vyhledávání - "Laura S. Jacobus"

Akademický článek

Leveraging oncology collaborative networks and biomedical informatics data resources to rapidly recruit and enroll rural residents into oncology quality of life clinical trials

Autor: Heath A. Davis, Asher A. Hoberg, Laura S. Jacobus, Kenneth Nepple, Aaron T. Seaman, Jamie Sorensen, George J. Weiner, Stephanie Gilbertson-White

Publikováno v: Journal of Clinical and Translational Science, Vol 8 (2024)

Abstract Purpose: This study assesses the feasibility of biomedical informatics resources for efficient recruitment of rural residents with cancer to a clinical trial of a quality-of-life (QOL) mobile app. These resources have the potential to reduc

Externí odkaz: https://doaj.org/article/2d3ab48013144daea6d5af2d4d286dd8

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The impact of HRD in patients with pancreatic adenocarcinoma undergoing surgical resection: An updated analysis

Autor: Gudbjorg Jonsdottir, Asgeir Thor Masson, Laura S. Jacobus, Michelle L. Churchman, Stephen B. Edge, Anne M. Noonan, Michael J. Cavnar, Susanna Varkey Ulahannan, Ibrahim Halil Sahin, Carlos Hou Fai Chan

Publikováno v: Journal of Clinical Oncology. 40:4132-4132

4132 Background: Limited data is available regarding which mutations in the homologous recombination repair (HRR) pathway beyond BRCA can be targeted with platinum-based chemotherapy in the perioperative setting in patients with pancreatic ductal ade

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::009616d549b080c32ed7c4be6ca4e5aa
https://doi.org/10.1200/jco.2022.40.16_suppl.4132

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The impact of germline and somatic mutations in the homologous recombination repair pathway in pancreatic cancer patients who undergo perioperative chemotherapy

Publikováno v: Journal of Clinical Oncology. 40:602-602

602 Background: Limited data is available regarding the effects of germline and somatic mutations in the homologous recombination repair (HRR) pathway in patients with resectable pancreatic cancer and exactly which mutations can be targeted with plat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::78a456445e201610e05036bc23eddbe6
https://doi.org/10.1200/jco.2022.40.4_suppl.602

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Identifying risk factors for preeclampsia in subsequent pregnancies in women with a history of preeclampsia

Autor: Kellie Thomas, Laura S. Jacobus, Debra Brandt, Michaela R Wiltgen, Donna A. Santillan, Heather Davis, Adam M Fitzsimmons, Mark K. Santillan, Lindsay K. Krotz

Publikováno v: Proceedings in Obstetrics and Gynecology. 8:1-2

Preeclampsia (PE) is a prevalent hypertensive disorder of pregnancy that causes significant maternal-fetal mortality. It has been reported that 60% of maternal mortality can be prevented. Studies have demonstrated that nursing has the ability to infl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5171b00d370d754abc65dc6b55329152
https://doi.org/10.17077/2154-4751.1430

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18-Fluoro-deoxyglucose positron emission tomography report interpretation as predictor of outcome in diffuse large B-cell lymphoma including analysis of ‘indeterminate’ reports

Autor: Brian K. Link, Alexandra Thomas, Laura S. Jacobus, Roger D. Gingrich, Brian J. Smith, Kay M. Ristow, Matthew J. Maurer, Thomas M. Habermann, Cristine Allmer

Publikováno v: Leukemia & Lymphoma. 51:439-446

This study evaluates the predictive value of post-therapy 18-fluoro-deoxyglucose positron emission tomography (FDG-PET), including indeterminate studies, following curative-intent therapy in diffuse large B-cell lymphoma (DLBCL). Consecutive patients

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cbbb5f72ae301cb097f7abb83c56a8d
https://doi.org/10.3109/10428190903560198

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Rituximab infusion induces NK activation in lymphoma patients with the high-affinity CD16 polymorphism

Autor: Tina Knutson, Laura S. Jacobus, Brian K. Link, Christopher E. Dahle, Suresh Veeramani, George J. Weiner, Anna M. Button, Siao-Yi Wang, Sue E. Blackwell

Publikováno v: Blood. 118:3347-3349

Natural killer (NK) cell–mediated antibody-dependent cellular cytotoxicity involving FcγRIIIa (CD16) likely contributes to the clinical efficacy of rituximab. To assess the in vivo effects of CD16 polymorphisms on rituximab-induced NK activation,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09d3eb2740b13fdbafbe0028475b8efa
https://doi.org/10.1182/blood-2011-05-351411

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B-chronic lymphocytic leukemia cells and other B cells can produce granzyme B and gain cytotoxic potential after interleukin-21-based activation

Autor: James E. Wooldridge, Bernd Jahrsdörfer, Sue E. Blackwell, Christiana M. Taylor, George J. Weiner, Melinda W. Andreski, Jian Huang, Laura S. Jacobus

B cells currently are not viewed as being capable of producing granzyme B or being cytotoxic. We found that B-chronic lymphocytic leukemia (B-CLL) cells treated with interleukin-21 (IL-21) produce low levels of granzyme B. The addition of either CpG

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0bfa1b6e9dca1bfb13dbb019234f7a6
https://europepmc.org/articles/PMC1895576/

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Complement Factor H Related Protein 1 (CFHR1) Serum Level Correlates With Event-Free Survival In Follicular Lymphoma Patients Treated With Rituximab

Autor: Laura M Rogers, Laura S. Jacobus, Anna M Button, Brian K Link, Thomas M Habermann, Thomas E Witzig, James R Cerhan, George J. Weiner

Publikováno v: Blood. 122:4288-4288

The anti-CD20 monoclonal antibody rituximab (R) is widely used to treat B-cell malignancies including follicular lymphoma (FL). A better understanding of activity and resistance mechanisms is necessary for improving treatment outcomes. We previously

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::213ecc8dd377fad2397eac8985dcdff2
https://doi.org/10.1182/blood.v122.21.4288.4288

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Identification of Candidate B-Lymphoma Genes by Cross-Species Gene Expression Profiling

Autor: Brian J. Smith, Zebin Wang, Brian K. Link, Alicia K. Olivier, Van S. Tompkins, Sergei Syrbu, Pradip Raychaudhuri, Thomas B. Bair, George J. Weiner, Seong-Su Han, Herbert C. Morse, Anna M. Button, Laura S. Jacobus, Samuel Lifton, Siegfried Janz

Publikováno v: PLoS ONE
PLoS ONE, Vol 8, Iss 10, p e76889 (2013)

Comparative genome-wide expression profiling of malignant tumor counterparts across the human-mouse species barrier has a successful track record as a gene discovery tool in liver, breast, lung, prostate and other cancers, but has been largely neglec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc79ffe4e8c1111d691f4224b1fcb5c0
https://doi.org/10.1371/journal.pone.0076889

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