Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Laura S. Handal"'
Autor:
Nathaniel S. Chapman, Ruben J. G. Hulswit, Jonna L. B. Westover, Robert Stass, Guido C. Paesen, Elad Binshtein, Joseph X. Reidy, Taylor B. Engdahl, Laura S. Handal, Alejandra Flores, Brian B. Gowen, Thomas A. Bowden, James E. Crowe
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract The zoonotic Rift Valley fever virus (RVFV) can cause severe disease in humans and has pandemic potential, yet no approved vaccine or therapy exists. Here we describe a dual-mechanism human monoclonal antibody (mAb) combination against RVFV
Externí odkaz:
https://doaj.org/article/b9951ffe5c244d7b912906b85005d70b
Autor:
Cynthia M. McMillen, Nathaniel S. Chapman, Ryan M. Hoehl, Lauren B. Skvarca, Madeline M. Schwarz, Laura S. Handal, James E. Crowe, Amy L. Hartman
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Rift Valley fever virus (RVFV) is an emerging mosquito-transmitted virus that circulates in livestock and humans in Africa and the Middle East. Outbreaks lead to high rates of miscarriages in domesticated livestock. Women are also at risk of
Externí odkaz:
https://doaj.org/article/b005e172a9a3481db7bdb83e145d536f
Autor:
Naveenchandra Suryadevara, Andrea R. Shiakolas, Laura A. VanBlargan, Elad Binshtein, Rita E. Chen, James Brett Case, Kevin J. Kramer, Erica C. Armstrong, Luke Myers, Andrew Trivette, Christopher Gainza, Rachel S. Nargi, Christopher N. Selverian, Edgar Davidson, Benjamin J. Doranz, Summer M. Diaz, Laura S. Handal, Robert H. Carnahan, Michael S. Diamond, Ivelin S. Georgiev, James E. Crowe Jr.
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 11 (2022)
The protective human antibody response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) focuses on the spike (S) protein, which decorates the virion surface and mediates cell binding and entry. Most SARS-CoV-2 protective antibodies tar
Externí odkaz:
https://doaj.org/article/9fba5e9f15e74bbdb3531fad2680cb32
Autor:
Rebecca L Brocato, Elad Binshtein, Taylor B Engdahl, Natalia A Kuzmina, Lucia M Principe, Steven A Kwilas, Robert K Kim, Nathaniel S Chapman, Monique S Porter, Pablo Guardado-Calvo, Félix A Rey, Laura S Handal, Summer M Diaz, Irene A Zagol-Ikapitte, Minh H Tran, W Hayes McDonald, Jens Meiler, Joseph X Reidy, Andrew Trivette, Alexander Bukreyev, Jay W Hooper, James E Crowe
Publikováno v:
eLife
eLife, 2023, 12, ⟨10.7554/eLife.81743⟩
eLife, 2023, 12, ⟨10.7554/eLife.81743⟩
International audience; Hantaviruses are high-priority emerging pathogens carried by rodents and transmitted to humans by aerosolized excreta or, in rare cases, person-to-person contact. While infections in humans are relatively rare, mortality rates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c5bfe7749db7fdcccc05740700dacd1
https://hal-pasteur.archives-ouvertes.fr/pasteur-04123202/document
https://hal-pasteur.archives-ouvertes.fr/pasteur-04123202/document
Autor:
Rebecca L Brocato, Elad Binshtein, Taylor B Engdahl, Natalia A Kuzmina, Lucia M Principe, Steven A Kwilas, Robert K Kim, Nathaniel S Chapman, Monique S Porter, Pablo Guardado-Calvo, Félix A Rey, Laura S Handal, Summer M Diaz, Irene A Zagol-Ikapitte, Minh H Tran, W Hayes McDonald, Jens Meiler, Joseph X Reidy, Andrew Trivette, Alexander Bukreyev, Jay W Hooper, James E Crowe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd2898d4a7ab66a28e0fcccd03e45a64
https://doi.org/10.7554/elife.81743.sa2
https://doi.org/10.7554/elife.81743.sa2
Autor:
Thomas A. Desautels, Kathryn T. Arrildt, Adam T. Zemla, Edmond Y. Lau, Fangqiang Zhu, Dante Ricci, Stephanie Cronin, Seth J. Zost, Elad Binshtein, Suzanne M. Scheaffer, Bernadeta Dadonaite, Brenden K. Petersen, Taylor B. Engdahl, Elaine Chen, Laura S. Handal, Lynn Hall, John W. Goforth, Denis Vashchenko, Sam Nguyen, Dina R. Weilhammer, Jacky Kai-Yin Lo, Bonnee Rubinfeld, Edwin A. Saada, Tracy Weisenberger, Tek-Hyung Lee, Bradley Whitener, James B. Case, Alexander Ladd, Mary S. Silva, Rebecca M. Haluska, Emilia A. Grzesiak, Christopher G. Earnhart, Svetlana Hopkins, Thomas W. Bates, Larissa B. Thackray, Brent W. Segelke, Antonietta Maria Lillo, Shivshankar Sundaram, Jesse Bloom, Michael S. Diamond, James E. Crowe, Robert H. Carnahan, Daniel M. Faissol
Publikováno v:
bioRxiv : the preprint server for biology.
The COVID-19 pandemic underscored the promise of monoclonal antibody-based prophylactic and therapeutic drugs1–3, but also revealed how quickly viral escape can curtail effective options4, 5. With the emergence of the SARS-CoV-2 Omicron variant in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54ff1afccb0a13a81d61afc37c7aa6a7
https://pubmed.ncbi.nlm.nih.gov/36324800
https://pubmed.ncbi.nlm.nih.gov/36324800
Autor:
Taylor B. Engdahl, Elad Binshtein, Rebecca L. Brocato, Natalia A. Kuzmina, Lucia M Principe, Steven A. Kwilas, Robert K. Kim, Nathaniel S. Chapman, Monique S. Porter, Pablo Guardado-Calvo, Felix A. Rey, Laura S. Handal, Summer M. Diaz, Irene A. Zagol-Ikapitte, Joseph X. Reidy, Andrew Trivette, Alexander Bukreyev, Jay W. Hooper, James. E. Crowe
Hantaviruses are high-priority emerging pathogens carried by rodents and transmitted to humans by aerosolized excreta or, in rare cases, person-to-person contact. While sporadic in North and South America, many infections occur in Europe and Asia, wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::efaa40449c0d4e58e0565078a0cf06a3
https://doi.org/10.1101/2022.07.19.500579
https://doi.org/10.1101/2022.07.19.500579
Autor:
Benjamin D. Fowler, Nurgun Kose, Joseph X. Reidy, Laura S. Handal, Eric P. Skaar, James E. Crowe
Publikováno v:
Infect Immun
Escherichia coli is one of the most frequent human pathogens, increasingly exhibits antimicrobial resistance, and has complex interactions with the host immune system. E. coli exposure or infection can result in the generation of antibodies specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1bd8f74878b6bdc5aefe02015daa5a3
https://europepmc.org/articles/PMC9202393/
https://europepmc.org/articles/PMC9202393/
Autor:
Taylor B Engdahl, Elad Binshtein, Rebecca L Brocato, Natalia A Kuzmina, Lucia M Principe, Steven A Kwilas, Robert K Kim, Nathaniel S Chapman, Monique S Porter, Pablo Guardado-Calvo, Félix A Rey, Laura S Handal, Summer M Diaz, Irene A Zagol-Ikapitte, Minh H Tran, W Hayes McDonald, Jens Meiler, Joseph X Reidy, Andrew Trivette, Alexander Bukreyev, Jay W Hooper, James E Crowe
Publikováno v:
eLife, Vol 12 (2023)
Hantaviruses are high-priority emerging pathogens carried by rodents and transmitted to humans by aerosolized excreta or, in rare cases, person-to-person contact. While infections in humans are relatively rare, mortality rates range from 1 to 40% dep
Externí odkaz:
https://doaj.org/article/8473aa7cf9fd4f6f8543805191bc6878