Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Laura S Rojas-Hernandez"'
Autor:
Zofia Varenyiova, Laura S. Rojas-Hernandez, Jacquelyn Spano, Vaclav Capek, Yael Rosenberg-Hasson, Tyson Holmes, Carlos Milla
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Primary ciliary dyskinesia (PCD) is a genetic disorder associated with recurrent and chronic respiratory infections due to functional defects of motile cilia. In this study, we aimed to elucidate inflammatory and proliferative responses in P
Externí odkaz:
https://doaj.org/article/bf07f4aeb5cf40f7a022d641d383522a
Autor:
Medeea C. Popescu, Naomi L. Haddock, Elizabeth B. Burgener, Laura S. Rojas-Hernandez, Gernot Kaber, Aviv Hargil, Paul L. Bollyky, Carlos E. Milla
Publikováno v:
Viruses, Vol 16, Iss 1, p 165 (2024)
Background: The inovirus Pf4 is a lysogenic bacteriophage of Pseudomonas aeruginosa (Pa). People with Cystic Fibrosis (pwCF) experience chronic airway infection with Pa and a significant proportion have high numbers of Pf4 in their airway secretions.
Externí odkaz:
https://doaj.org/article/9fe7d46604d04d53acc440207a002477
Autor:
Eszter K. Vladar, Koshi Kunimoto, Laura S. Rojas-Hernandez, Jacquelyn M. Spano, Zachary M. Sellers, Nam Soo Joo, Riley A. Cooney, Jeffrey D. Axelrod, Carlos E. Milla
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 324:L771-L782
Our findings show that low-dose, short-term topical or systemic γ-secretase inhibitor treatment may lead to restoration of multiciliated cells without toxicity and potentially improve epithelial function in a wide range of chronic lung diseases.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e22e0a5a956ef85cf164f502bf26d711
https://doi.org/10.1152/ajplung.00382.2022
https://doi.org/10.1152/ajplung.00382.2022
Autor:
Medeea C Popescu, Naomi L Haddock, Elizabeth B Burgener, Laura S Rojas-Hernandez, Gernot Kaber, Aviv Hargil, Paul L Bollyky, Carlos E Milla
Basal airway epithelial cells are a multipotent stem cell population which gives rise to several airway cell types. Basal cells are known to be critical to airway epithelium homeostasis and repair, and altered basal cell phenotypes have been reported
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a40d62a3c05d829cd8ddf50168125c6
https://doi.org/10.1101/2022.09.27.509771
https://doi.org/10.1101/2022.09.27.509771
Autor:
Chien-Ting Wu, Peter V. Lidsky, Yinghong Xiao, Ran Cheng, Ivan T. Lee, Tsuguhisa Nakayama, Sizun Jiang, Wei He, Janos Demeter, Miguel G. Knight, Rachel E. Turn, Laura S. Rojas-Hernandez, Garry Nolan, Carlos Milla, Jayakar V. Nayak, Raul Andino, Peter K. Jackson
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c567297448cf9d4242c65da9a9070a05
https://doi.org/10.2139/ssrn.4089984
https://doi.org/10.2139/ssrn.4089984
Autor:
Chien-Ting Wu, Peter V. Lidsky, Yinghong Xiao, Ran Cheng, Ivan T. Lee, Tsuguhisa Nakayama, Sizun Jiang, Wei He, Janos Demeter, Miguel G. Knight, Rachel E. Turn, Laura S. Rojas-Hernandez, Chengjin Ye, Kevin Chiem, Judy Shon, Luis Martinez-Sobrido, Carolyn R. Bertozzi, Garry P. Nolan, Jayakar V. Nayak, Carlos Milla, Raul Andino, Peter K. Jackson
Publikováno v:
Cell. 186:112-130.e20
How SARS-CoV-2 penetrates the airway barrier of mucus and periciliary mucins to infect nasal epithelium remains unclear. Using primary nasal epithelial organoid cultures, we found that the virus attaches to motile cilia via the ACE2 receptor. SARS-Co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5b121f0f2c61f1e100123a7ef99118d
https://doi.org/10.1016/j.cell.2022.11.030
https://doi.org/10.1016/j.cell.2022.11.030
Autor:
Xiaokui Mo, Jessica L. Cooperstone, Jinmai Jiang, Laura S. Rojas-Hernandez, Andrea I. Doseff, Mayra Diosa-Toro, Thomas D. Schmittgen, Daniel Arango, Steven J. Schwartz
Publikováno v:
Mol Nutr Food Res
Scope High incidence of inflammatory diseases afflicts the increasing aging-population infringing a great health burden. Dietary flavonoids, including the flavone apigenin, are emerging as important anti-inflammatory nutraceuticals due to their healt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23b0893ff6bedbb164c017dd5f3ace22
https://europepmc.org/articles/PMC7955240/
https://europepmc.org/articles/PMC7955240/