Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Laura Rubio‐Pérez"'
Autor:
Rodrigo Lázaro‐Gorines, Patricia Pérez, Ignacio Heras‐Murillo, Irene Adán‐Barrientos, Guillermo Albericio, David Astorgano, Sara Flores, Joanna Luczkowiak, Nuria Labiod, Seandean L. Harwood, Alejandro Segura‐Tudela, Laura Rubio‐Pérez, Yudhi Nugraha, Xiaoran Shang, Yuxing Li, Carlos Alfonso, Kaylin A. Adipietro, Dinendra L. Abeyawardhane, Rocío Navarro, Marta Compte, Wenbo Yu, Alexander D. MacKerell Jr, Laura Sanz, David J. Weber, Francisco J. Blanco, Mariano Esteban, Edwin Pozharski, Raquel Godoy‐Ruiz, Inés G. Muñoz, Rafael Delgado, David Sancho, Juan García‐Arriaza, Luis Álvarez‐Vallina
Publikováno v:
Advanced Science, Vol 10, Iss 34, Pp n/a-n/a (2023)
Abstract Administration of neutralizing antibodies (nAbs) has proved to be effective by providing immediate protection against SARS‐CoV‐2. However, dual strategies combining virus neutralization and immune response stimulation to enhance specific
Externí odkaz:
https://doaj.org/article/83ee823ecfc342e88a1c1efafa321622
Autor:
Laura Rubio-Pérez, Rodrigo Lázaro-Gorines, Seandean L. Harwood, Marta Compte, Rocío Navarro, Antonio Tapia-Galisteo, Jaume Bonet, Belén Blanco, Simon Lykkemark, Ángel Ramírez-Fernández, Mariola Ferreras-Gutiérrez, Carmen Domínguez-Alonso, Laura Díez-Alonso, Alejandro Segura-Tudela, Oana Hangiu, Ainhoa Erce-Llamazares, Francisco J. Blanco, Cruz Santos, José L. Rodríguez-Peralto, Laura Sanz, Luis Álvarez-Vallina
Publikováno v:
OncoImmunology, Vol 12, Iss 1 (2023)
ABSTRACTImmune checkpoint blockade (ICB) with antibodies has shown durable clinical responses in a wide range of cancer types, but the overall response rate is still limited. Other effective therapeutic modalities to increase the ICB response rates a
Externí odkaz:
https://doaj.org/article/87732fe8a8464638935a3dfe1b8c3ab0
Autor:
Laura Rubio-Pérez, Susana Frago, Marta Compte, Rocío Navarro, Seandean L. Harwood, Rodrigo Lázaro-Gorines, Marina Gómez-Rosel, Oana Hangiu, Noelia Silva-Pilipich, Lucía Vanrell, Cristian Smerdou, Luis Álvarez-Vallina
Publikováno v:
Antibodies, Vol 13, Iss 2, p 34 (2024)
Immune checkpoint blockade has changed the treatment paradigm for advanced solid tumors, but the overall response rates are still limited. The combination of checkpoint blockade with anti-4-1BB antibodies to stimulate tumor-infiltrating T cells has s
Externí odkaz:
https://doaj.org/article/f4146a3dc0ce4049b9e43fa900b61edb
Autor:
Oana Hangiu, Marta Compte, Anders Dinesen, Rocio Navarro, Antonio Tapia-Galisteo, Ole A. Mandrup, Ainhoa Erce-Llamazares, Rodrigo Lázaro-Gorines, Daniel Nehme-Álvarez, Carmen Domínguez-Alonso, Seandean L. Harwood, Carlos Alfonso, Belen Blanco, Laura Rubio-Pérez, Anaïs Jiménez-Reinoso, Laura Díez-Alonso, Francisco J. Blanco, Laura Sanz, Kenneth A. Howard, Luis Álvarez-Vallina
Publikováno v:
iScience, Vol 25, Iss 9, Pp 104958- (2022)
Summary: Costimulation of tumor-infiltrating T lymphocytes by anti-4-1BB monoclonal antibodies (mAbs) has shown anti-tumor activity in human trials, but can be associated with significant off-tumor toxicities involving FcγR interactions. Here, we in
Externí odkaz:
https://doaj.org/article/c486f101097e4624bed914bc95a337c3
Autor:
Luis Álvarez-Vallina, Pablo Menéndez, Manel Juan, Pedro Roda-Navarro, María L. Toribio, Laura Sanz, Sonia Guedan, Estela Paz-Artal, Pablo Morales, Maria Neves, Carmen Domínguez-Alonso, Anaïs Jiménez-Reinoso, Laura Rubio-Pérez, Ainhoa Erce-Llamazares, Simon Lykkemark, Marta Compte, Seandean L. Harwood, Sergi Betriu, Berta Marzal, Maria Castellà, Alejandro Segura-Tudela, Laura Díez-Alonso, Antonio Tapia-Galisteo, Samanta Romina Zanetti, Francisco Gutierrez-Agüera, Óscar Aguilar-Sopeña, Patricia Fuentes, Lidia Argemí-Muntadas, Clara Bueno, Ángel Ramírez-Fernández, Belén Blanco
Supplementary Data from Overcoming CAR-Mediated CD19 Downmodulation and Leukemia Relapse with T Lymphocytes Secreting Anti-CD19 T-cell Engagers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::181012a204af0f13777e162dffd1b6b5
https://doi.org/10.1158/2326-6066.22544789
https://doi.org/10.1158/2326-6066.22544789
Autor:
Luis Álvarez-Vallina, Pablo Menéndez, Manel Juan, Pedro Roda-Navarro, María L. Toribio, Laura Sanz, Sonia Guedan, Estela Paz-Artal, Pablo Morales, Maria Neves, Carmen Domínguez-Alonso, Anaïs Jiménez-Reinoso, Laura Rubio-Pérez, Ainhoa Erce-Llamazares, Simon Lykkemark, Marta Compte, Seandean L. Harwood, Sergi Betriu, Berta Marzal, Maria Castellà, Alejandro Segura-Tudela, Laura Díez-Alonso, Antonio Tapia-Galisteo, Samanta Romina Zanetti, Francisco Gutierrez-Agüera, Óscar Aguilar-Sopeña, Patricia Fuentes, Lidia Argemí-Muntadas, Clara Bueno, Ángel Ramírez-Fernández, Belén Blanco
Chimeric antigen receptor (CAR)–modified T cells have revolutionized the treatment of CD19-positive hematologic malignancies. Although anti-CD19 CAR-engineered autologous T cells can induce remission in patients with B-cell acute lymphoblastic leuk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49490124e8ea631de7040033e3b6522b
https://doi.org/10.1158/2326-6066.c.6550748.v1
https://doi.org/10.1158/2326-6066.c.6550748.v1
Autor:
Laura Rubio-Pérez, Ana Luque, Luis A. Oro, Julen Munarriz, Vincenzo Passarelli, Victor Polo, Manuel Iglesias, Amaia Iturmendi
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Dedicated to Prof. Ekkehardt Hahn on the occasion of his 65th birthday with our most sincere congratulations for his leadership and his many diverse and creative contributions to the field of Organometallic Chemistry, and best wishes.
The use of
The use of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb8e3bd6c24121d8faa9ff52bb8b79b3
https://doi.org/10.1016/j.jorganchem.2020.121259
https://doi.org/10.1016/j.jorganchem.2020.121259
Publikováno v:
Zaguán: Repositorio Digital de la Universidad de Zaragoza
Universidad de Zaragoza
Zaguán. Repositorio Digital de la Universidad de Zaragoza
instname
Digital.CSIC. Repositorio Institucional del CSIC
Universidad de Zaragoza
Zaguán. Repositorio Digital de la Universidad de Zaragoza
instname
Digital.CSIC. Repositorio Institucional del CSIC
New Ir–IPr complexes featuring a variety of chelate ligands, some of them featuring NH moieties, were synthesized. These complexes proved to be efficient catalysts for the dehydrogenation of formic acid in DMF and H2O. The dehydrogenation rates wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2102a87a130ca8f9ae4c4ae274acdad
http://hdl.handle.net/10261/177144
http://hdl.handle.net/10261/177144
Autor:
Laura Rubio-Pérez, Julen Munarriz, Manuel Iglesias, Luis A. Oro, Vincenzo Passarelli, Victor Polo, Jesús J. Pérez-Torrente
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Zaguán. Repositorio Digital de la Universidad de Zaragoza
instname
Zaguán. Repositorio Digital de la Universidad de Zaragoza
This article is part of the themed collection: Celebrating our 2018 prize and award winners.
A well-defined NHC-Ir(iii) catalyst, [Ir(H)(IPr)(py)][BF] (IPr = 1,3-bis-(2,6-diisopropylphenyl)imidazol-2-ylidene), that provides access to a wide rang
A well-defined NHC-Ir(iii) catalyst, [Ir(H)(IPr)(py)][BF] (IPr = 1,3-bis-(2,6-diisopropylphenyl)imidazol-2-ylidene), that provides access to a wide rang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0794375e7645f7df3489e22b513fa6f
http://hdl.handle.net/10261/177125
http://hdl.handle.net/10261/177125
Autor:
Victor Polo, Luis A. Oro, Jesús J. Pérez-Torrente, Ricardo Castarlenas, Manuel Iglesias, Laura Rubio-Pérez
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
[Rh(μ-Cl)(H)2(IPr)]2 (IPr=1,3-bis-(2,6-diisopropylphenyl)imidazol-2-ylidene) catalyzes the selective functionalization of 2-(2-thienyl)pyridine efficiently with a range of alkenes and internal alkynes. A catalytic cycle is proposed on the basis of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c733df89c4ef74698b119bf72b5ae64
https://doi.org/10.1002/cctc.201402507
https://doi.org/10.1002/cctc.201402507