Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Laura Restrepo-Pérez"'
Autor:
Giovanni Maglia, Rienk Eelkema, Cees Dekker, Gang Huang, Chirlmin Joo, Nathalie Worp, Laura Restrepo-Pérez, Peggy R. Bohländer
Publikováno v:
ACS Nano
While DNA sequencing is now amply available, fast, and inexpensive, protein sequencing remains a tremendous challenge. Nanopores may allow for developing a protein sequencer with single-molecule capabilities. As identification of 20 different amino a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67c7eb066b1ef2486b1d085f61e47e96
https://doi.org/10.1021/acsnano.0c01699
https://doi.org/10.1021/acsnano.0c01699
Publikováno v:
Nature Nanotechnology
Proteins are major building blocks of life. The protein content of a cell and an organism provides key information for the understanding of biological processes and disease. Despite the importance of protein analysis, only a handful of techniques are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd529843e45ff73e193effe438c3fd55
https://doi.org/10.1038/s41565-018-0236-6
https://doi.org/10.1038/s41565-018-0236-6
Resolving Chemical Modifications to a Single Amino Acid within a Peptide Using a Biological Nanopore
Autor:
Giovanni Maglia, Rienk Eelkema, Peggy R. Bohländer, Chirlmin Joo, Gang Huang, Cees Dekker, Laura Restrepo-Pérez, Nathalie Worp
Publikováno v:
Acs Nano, 13(12), 13668-13676. AMER CHEMICAL SOC
ACS Nano
ACS Nano (online), 13(12)
ACS Nano
ACS Nano (online), 13(12)
While DNA sequencing is now amply available, fast, and inexpensive, protein sequencing remains a tremendous challenge. Nanopores may allow for developing a protein sequencer with single-molecule capabilities. As identification of 20 different amino a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62a3cefc8c2ddfdc9816817f202c8806
https://research.rug.nl/en/publications/55780171-16d8-49d0-8859-24ab3c932b28
https://research.rug.nl/en/publications/55780171-16d8-49d0-8859-24ab3c932b28
Publikováno v:
Nano Letters, 19(11), 7957-7964. AMER CHEMICAL SOC
Nano Letters
Nano Letters: a journal dedicated to nanoscience and nanotechnology, 19(11)
Nano Letters
Nano Letters: a journal dedicated to nanoscience and nanotechnology, 19(11)
Post-translational modifications (PTMs) of proteins play key roles in cellular processes. Hence, PTM identification is crucial for elucidating the mechanism of complex cellular processes and disease. Here we present a method for PTM detection at the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef493cb995b95f623b56623c44094609
https://research.rug.nl/en/publications/e57e3f29-8374-42b5-bedc-30f2d7c96730
https://research.rug.nl/en/publications/e57e3f29-8374-42b5-bedc-30f2d7c96730
Autor:
Shidi Zhao, Aleksei Aksimentiev, Giovanni Maglia, Cees Dekker, Chirlmin Joo, Laura Restrepo-Pérez, Misha Soskine
Publikováno v:
Acs Nano, 13(2), 2398-2409. AMER CHEMICAL SOC
ACS Nano
ACS Nano (online), 13(2)
ACS Nano
ACS Nano (online), 13(2)
Ion channels form the basis of information processing in living cells by facilitating the exchange of electrical signals across and along cellular membranes. Applying the same principles to man-made systems requires the development of synthetic ion c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eee6626480b19807393dd7a692b848a7
https://research.rug.nl/en/publications/5c4fecb3-f859-4616-87a8-fa0026b76c02
https://research.rug.nl/en/publications/5c4fecb3-f859-4616-87a8-fa0026b76c02
Publikováno v:
Nanoscale
Nanoscale, 9(32)
Nanoscale, 9(32)
Using nanopores for the single-molecule sequencing of proteins – similar to nanopore-based sequencing of DNA – faces multiple challenges, including unfolding of the complex tertiary structure of the proteins and enforcing their unidirectional tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a39e19509df3ab8d8fbcbfdd51850af2
Autor:
Aleksei Aksimentiev, Shalini John, Misha Soskine, Laura Restrepo-Pérez, Giovanni Maglia, Cees Dekker, Chirlmin Joo
Publikováno v:
Biophysical Journal. 112:330a
Proteins are the most abundant biomolecules in the human body. Proteomics is instrumental to understand and detect diseases. Despite the importance of protein analysis, only a handful of techniques are available to determine protein sequences and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e322faeb2860680b136b3b7c8aee5b90
https://doi.org/10.1016/j.bpj.2016.11.1789
https://doi.org/10.1016/j.bpj.2016.11.1789
Autor:
Samuel Sanchez, Lluís Soler, Laura Restrepo-Pérez, Oliver G. Schmidt, Cynthia S. Martínez-Cisneros
Publikováno v:
UPCommons. Portal del coneixement obert de la UPC
Universitat Politècnica de Catalunya (UPC)
Recercat. Dipósit de la Recerca de Catalunya
Universitat Jaume I
Lab on a Chip
e-Archivo. Repositorio Institucional de la Universidad Carlos III de Madrid
instname
Universitat Politècnica de Catalunya (UPC)
Recercat. Dipósit de la Recerca de Catalunya
Universitat Jaume I
Lab on a Chip
e-Archivo. Repositorio Institucional de la Universidad Carlos III de Madrid
instname
Biofunctionalized self-propelled micromotors combined with microchips are alternative concentrating systems. No external energy source is required, facilitating integration and miniaturization.
Sample pre-concentration is crucial to achieve high
Sample pre-concentration is crucial to achieve high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e665957665c647d303945abf1205b649
https://hdl.handle.net/10016/26735
https://hdl.handle.net/10016/26735
Autor:
Jaco van der Torre, Cees Dekker, Anthony Birnie, Michel Bengtson, Laura Restrepo-Pérez, Stephanie J. Heerema, Wayne Yang
Publikováno v:
Nano Letters
Nano Letters: a journal dedicated to nanoscience and nanotechnology
Nano Letters: a journal dedicated to nanoscience and nanotechnology
Solid-state nanopores have emerged as promising platforms for biosensing including diagnostics for disease detection. Here we show nanopore experiments that detect CRISPR-dCas9, a sequence-specific RNA-guided protein system that specifically binds to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e2e20aabb6256cd3c9cbd0e664f8970