Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Laura Ragona"'
Autor:
Simona Tomaselli, Fabio Bertini, Angelica Cifarelli, Adriano Vignali, Laura Ragona, Simona Losio
Publikováno v:
Molecules, Vol 28, Iss 4, p 1966 (2023)
Water-blown polyurethane (PU) foams were prepared by bio-polyols from epoxidized linseed oils and caprylic acid in combination with toluene diisocianate (TDI). A series of terpenes (menthol, geraniol, terpineol, and borneol), natural compounds with r
Externí odkaz:
https://doaj.org/article/11337077c11b4b6d8677804930c49889
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Alzheimer’s disease (AD) is one of the most common neurodegenerative disorders, with no cure and preventive therapy. Misfolding and extracellular aggregation of Amyloid-β (Aβ) peptides are recognized as the main cause of AD progression, leading t
Externí odkaz:
https://doaj.org/article/878361269cee42229ed8a6d9027e1e4d
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97153 (2014)
In this paper, we investigate the dynamic aspects of the molecular recognition between a small molecule ligand and a flat, exposed protein surface, representing a typical target in the development of protein-protein interaction inhibitors. Specifical
Externí odkaz:
https://doaj.org/article/6d46df0df8534984818e40717608e3c5
Autor:
Katiuscia Pagano, Simona Tomaselli, Serena Zanzoni, Michael Assfalg, Henriette Molinari, Laura Ragona
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 6, Iss 7 (2013)
During the last decade a growing amount of evidence has been obtained, supporting the role of the beta-clamshell family of intracellular lipid binding proteins (iLBPs) not only in the translocation of lipophilic molecules but also in lipid mediated s
Externí odkaz:
https://doaj.org/article/f6f40a6bd51247859685d7befd212183
Autor:
Katiuscia Pagano, Rubben Torella, Chiara Foglieni, Antonella Bugatti, Simona Tomaselli, Lucia Zetta, Marco Presta, Marco Rusnati, Giulia Taraboletti, Giorgio Colombo, Laura Ragona
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36990 (2012)
Fibroblast growth factors (FGFs) are recognized targets for the development of therapies against angiogenesis-driven diseases, including cancer. The formation of a ternary complex with the transmembrane tyrosine kinase receptors (FGFRs), and heparan
Externí odkaz:
https://doaj.org/article/061b20b1ac724c3e97bcd6d72331e2bd
Autor:
Patricia Perez Schmidt, Katiuscia Pagano, Cristina Lenardi, Marta Penconi, Ruth Mateu Ferrando, Claudio Evangelisti, Luigi Lay, Laura Ragona, Marcello Marelli, Laura Polito
Ultra-small gold nanoparticles (UAuNPs) are extremely interesting for applications in nanomedicine thanks to their good stability, biocompatibility, long circulation time and efficient clearance pathways. UAuNPs engineered with glycans (Glyco-UAuNPs)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::648d98a7a11a3f37c8310871eb005159
https://hdl.handle.net/2434/945937
https://hdl.handle.net/2434/945937
Autor:
Katiuscia Pagano, Roberta Listro, Pasquale Linciano, Daniela Rossi, Elisa Longhi, Giulia Taraboletti, Henriette Molinari, Simona Collina, Laura Ragona
Publikováno v:
Bioorganic Chemistry. 136:106529
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 18; Pages: 10860
NMR-based approaches play a pivotal role in providing insight into molecular recognition mechanisms, affording the required atomic-level description and enabling the identification of promising inhibitors of protein–protein interactions. The aberra
Autor:
Simona Tomaselli, Mariacecilia Pasini, Erika Kozma, Umberto Giovanella, Guido Scavia, Katiuscia Pagano, Henriette Molinari, Salvatore Iannace, Laura Ragona
Publikováno v:
Biochimica et biophysica acta. General subjects. 1867(1)
Cells exposed to stress factors experience time-dependent variations of metabolite concentration, acting as reliable sensors of the effective concentration of drugs in solution. NMR can detect and quantify changes in metabolite concentration, thus pr
Autor:
Gianluigi Forloni, Pietro La Vitola, Luca Banfi, Giulia Santamaria, Claudia Fracasso, Denise Galante, Claudia Balducci, Jacopo Lucchetti, Chiara Lambruschini, Laura Ragona, Simona Tomaselli, Cristina D'Arrigo, Edoardo Brandi, Katiuscia Pagano, Lisa Moni, Henriette Molinari
Publikováno v:
ACS Chemical Neuroscience. 10:4462-4475
In this study natural-based complex polyphenols, obtained through a smart synthetic approach, have been evaluated for their ability to inhibit the formation of Aβ42 oligomers, the most toxic species causing synaptic dysfunction, neuroinflammation, a