Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Laura Radić"'
Autor:
Denise Guerra, Laura Radić, Mitch Brinkkemper, Meliawati Poniman, Lara van der Maas, Jonathan L. Torres, Andrew B. Ward, Kwinten Sliepen, Janke Schinkel, Rogier W. Sanders, Marit J. van Gils, Tim Beaumont
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 20, Iss 1 (2024)
Monoclonal neutralizing antibodies (mAbs) are considered an important prophylactic against SARS-CoV-2 infection in at-risk populations and a strategy to counteract future sarbecovirus-induced disease. However, most mAbs isolated so far neutralize onl
Externí odkaz:
https://doaj.org/article/1fbcc6e3d1d94ac096e091f76a23bb0a
Autor:
Joan Capella-Pujol, Marlon de Gast, Laura Radić, Ian Zon, Ana Chumbe, Sylvie Koekkoek, Wouter Olijhoek, Janke Schinkel, Marit J. van Gils, Rogier W. Sanders, Kwinten Sliepen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract An effective preventive vaccine for hepatitis C virus (HCV) remains a major unmet need. Antigenic region 3 (AR3) on the E1E2 envelope glycoprotein complex overlaps with the CD81 receptor binding site and represents an important epitope for b
Externí odkaz:
https://doaj.org/article/20fc85222ffc4339b25c15e9589db983
Autor:
Denise Guerra, Tim Beaumont, Laura Radić, Gius Kerster, Karlijn van der Straten, Meng Yuan, Jonathan L. Torres, Wen-Hsin Lee, Hejun Liu, Meliawati Poniman, Ilja Bontjer, Judith A. Burger, Mathieu Claireaux, Tom G. Caniels, Jonne L. Snitselaar, Tom P.L. Bijl, Sabine Kruijer, Gabriel Ozorowski, David Gideonse, Kwinten Sliepen, Andrew B. Ward, Dirk Eggink, Godelieve J. de Bree, Ian A. Wilson, Rogier W. Sanders, Marit J. van Gils
Publikováno v:
iScience, Vol 26, Iss 10, Pp 108009- (2023)
Summary: The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has remained a medical threat due to the evolution of multiple variants that acquire resistance to vaccines and prior infection. Therefore, it is imperative
Externí odkaz:
https://doaj.org/article/3ad7176ab698474aa693e7f4597fd235
Autor:
Kwinten Sliepen, Laura Radić, Joan Capella-Pujol, Yasunori Watanabe, Ian Zon, Ana Chumbe, Wen-Hsin Lee, Marlon de Gast, Jelle Koopsen, Sylvie Koekkoek, Iván del Moral-Sánchez, Philip J. M. Brouwer, Rashmi Ravichandran, Gabriel Ozorowski, Neil P. King, Andrew B. Ward, Marit J. van Gils, Max Crispin, Janke Schinkel, Rogier W. Sanders
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
E1E2 spike on the hepatitis C virion is an important target for vaccine design. Here, the authors permute the subunits to generate E2E1 immunogens and show that mosaic nanoparticles displaying different E2E1 antigens elicit cross-neutralizing antibod
Externí odkaz:
https://doaj.org/article/4bc99bb0318e4c848fb64b60030bf5d0
Autor:
Laura Radić, Kwinten Sliepen, Victor Yin, Mitch Brinkkemper, Joan Capella-Pujol, Angela I. Schriek, Jonathan L. Torres, Sandhya Bangaru, Judith A. Burger, Meliawati Poniman, Ilja Bontjer, Joey H. Bouhuijs, David Gideonse, Dirk Eggink, Andrew B. Ward, Albert J.R. Heck, Marit J. Van Gils, Rogier W. Sanders, Janke Schinkel
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106540- (2023)
Summary: SARS-CoV-2 variants evade current monoclonal antibody therapies. Bispecific antibodies (bsAbs) combine the specificities of two distinct antibodies taking advantage of the avidity and synergy provided by targeting different epitopes. Here we
Externí odkaz:
https://doaj.org/article/7d8f8ca04b814e959ae9c06f1301b35e
Autor:
Joan Capella-Pujol, Marlon de Gast, Laura Radić, Ian Zon, Ana Chumbe, Sylvie Koekkoek, Wouter Olijhoek, Janke Schinkel, Marit J. van Gils, Rogier Sanders, Kwinten Sliepen
An effective preventive vaccine for hepatitis C virus (HCV) remains a major unmet need. Antigenic region 3 (AR3) on the E1E2 envelope glycoprotein complex overlaps with the CD81 receptor binding site and represents an important epitope for vaccine de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8540aa2a5ab4db402c485d9b90d5205b
https://doi.org/10.21203/rs.3.rs-2255626/v1
https://doi.org/10.21203/rs.3.rs-2255626/v1
Autor:
Denise Guerra, Tim Beaumont, Laura Radić, Gius Kerster, Karlijn van der Straten, Meng Yuan, Jonathan L. Torres, Wen-Hsin Lee, Hejun Liu, Meliawati Poniman, Ilja Bontjer, Judith A. Burger, Mathieu Claireaux, Tom G. Caniels, Jonne L. Snitselaar, Tom P. L. Bijl, Sabine Kruijer, Gabriel Ozorowski, David Gideonse, Kwinten Sliepen, Andrew B. Ward, Dirk Eggink, Godelieve J. de Bree, Ian A. Wilson, Rogier W. Sanders, Marit J. van Gils
Publikováno v:
bioRxiv
The worldwide pandemic caused by SARS-CoV-2 has remained a human medical threat due to the continued evolution of multiple variants that acquire resistance to vaccines and prior infection. Therefore, it is imperative to discover monoclonal antibodies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::755b93b9d8817822ecae32aca14c1dce
https://doi.org/10.1101/2022.10.14.512216
https://doi.org/10.1101/2022.10.14.512216