Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Laura R. Moody"'
Autor:
Matthew Boyce, Kristin A. Favela, Jessica A. Bonzo, Alex Chao, Lucina E. Lizarraga, Laura R. Moody, Elizabeth O. Owens, Grace Patlewicz, Imran Shah, Jon R. Sobus, Russell S. Thomas, Antony J. Williams, Alice Yau, John F. Wambaugh
Publikováno v:
Frontiers in Toxicology, Vol 5 (2023)
Understanding the metabolic fate of a xenobiotic substance can help inform its potential health risks and allow for the identification of signature metabolites associated with exposure. The need to characterize metabolites of poorly studied or novel
Externí odkaz:
https://doaj.org/article/7f0aa8ed5d56429591182f917881d06c
Publikováno v:
The Journal of biological chemistry. 292(14)
Mutations in the astrocyte-specific intermediate filament glial fibrillary acidic protein (GFAP) lead to the rare and fatal disorder, Alexander disease (AxD). A prominent feature of the disease is aberrant accumulation of GFAP. It has been proposed t
Publikováno v:
Prion. 3:99-109
Identification of genes expressed in response to prion infection may elucidate biomarkers for disease, identify factors involved in agent replication, mechanisms of neuropathology and therapeutic targets. Although several groups have sought to identi
Publikováno v:
Journal of toxicology and environmental health. Part A. 74(2-4)
Global gene expression analysis allows for the identification of transcripts that are differentially regulated during a disease state. Many groups, including our own, have identified hundreds of genes differentially regulated in response to prion inf