Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Laura R. Moffitt"'
Autor:
Amy L. Wilson, Laura R. Moffitt, Brittany R. Doran, Bashira Basri, Jennie Do, Thomas W. Jobling, Magdalena Plebanski, Andrew N. Stephens, Maree Bilandzic
Publikováno v:
Cell Reports, Vol 43, Iss 11, Pp 114979- (2024)
Summary: Over 75% of patients with ovarian cancer present with late-stage disease, often accompanied by extensive metastasis. The metastatic cascade is driven by a sub-population of transcriptionally plastic cells known as ''leader cells'' (LCs), whi
Externí odkaz:
https://doaj.org/article/07ac7e1916c64df88797af6b462673f3
Autor:
Amy L. Wilson, Brittany R. Doran, Bashirah Basri, Laura R. Moffitt, Magdalena Plebanski, Andrew N. Stephens, Maree Bilandzic
Publikováno v:
Cancer Research. 83:B040-B040
Epithelial ovarian cancer (EOC) is most frequently diagnosed at an advanced stage, and is characterized by its high recurrence rate and almost-universal acquisition of chemoresistance. Metastasis of EOC is driven by heterogenous spheroids that passiv
Autor:
Mark D. Gorrell, Amy L. Wilson, Laura R. Moffitt, Magdalena Plebanski, Andrew N. Stephens, Martin K. Oehler, Kirsty Wilson, Mark D Wright, Maree Bilandzic
Publikováno v:
Cancers, Vol 13, Iss 487, p 487 (2021)
Cancers
Volume 13
Issue 3
Cancers
Volume 13
Issue 3
Simple Summary The role of immunity in the development and progression of epithelial ovarian cancer (EOC) is well established. Poor T-cell infiltration is associated with mortality in EOC patients, and recent evidence has suggested that the enzyme DP
Autor:
Amy L. Wilson, Andrew N. Stephens, Martin K. Oehler, Maree Bilandzic, Mark D. Gorrell, Laura R. Moffitt, Magdalena Plebanski, Yiqian Chen
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 8110, p 8110 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 21
International Journal of Molecular Sciences
Volume 21
Issue 21
The treatment of ovarian cancer has not significantly changed in decades and it remains one of the most lethal malignancies in women. The serine protease dipeptidyl peptidase 4 (DPP4) plays key roles in metabolism and immunity, and its expression has
Autor:
Maree Bilandzic, Amy L. Wilson, Kirsty Wilson, Martin K. Oehler, Adam Rainczuk, Andrew N. Stephens, Laura R. Moffitt, Ming Makanji, Magdalena Plebanski, Mark D. Gorrell
Publikováno v:
Cancers
Volume 11
Issue 1
Cancers, Vol 11, Iss 1, p 32 (2018)
Volume 11
Issue 1
Cancers, Vol 11, Iss 1, p 32 (2018)
Ovarian cancers (OCs) are the most lethal gynaecological malignancy, with high levels of relapse and acquired chemo-resistance. Whilst the tumour&ndash
immune nexus controls both cancer progression and regression, the lack of an appropriate syst
immune nexus controls both cancer progression and regression, the lack of an appropriate syst
Autor:
Bashirah Basri, Laura R. Moffitt, Kirsty Wilson, Magdalena Plebanski, Amy L. Wilson, Andrew N. Stephens
Publikováno v:
Cancer Research. 80:5547-5547
Ovarian cancer is the most lethal gynecological malignancy and treatment options have not improved in decades. Whilst ovarian tumors have an immune-mediated component, emerging immunotherapies (e.g. anti-PD-1, anti-PD-L1) have failed to achieve robus
Autor:
Maree Bilandzic, Andrew N. Stephens, Laura R. Moffitt, Magdalena Plebanski, Amy L. Wilson, Kirsty Wilson
Publikováno v:
Cancer Immunology Research. 8:B69-B69
Ovarian cancers are the most lethal gynecologic malignancy, with high levels of relapse and acquired chemoresistance. Immunity clearly plays a role in ovarian tumor growth, but the inability to accurately correlate progression with stage-specific cha
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 20, Iss 6, p 1466 (2019)
International Journal of Molecular Sciences, Vol 20, Iss 6, p 1466 (2019)
Ovarian cancer is the seventh most commonly diagnosed cancer amongst women and has the highest mortality rate of all gynaecological malignancies. It is a heterogeneous disease attributed to one of three cell types found within the reproductive milieu