Zobrazeno 1 - 10 of 15 pro vyhledávání: '"Laura R. Inbody"'
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Akademický článek
G Protein-Coupled Receptor Kinase 2 Selectively Enhances β-Arrestin Recruitment to the D2 Dopamine Receptor through Mechanisms That Are Independent of Receptor Phosphorylation
Autor: Marta Sánchez-Soto, Noelia M. Boldizsar, Kayla A. Schardien, Nora S. Madaras, Blair K. A. Willette, Laura R. Inbody, Christopher Dasaro, Amy E. Moritz, Julia Drube, Raphael S. Haider, R. Benjamin Free, Carsten Hoffman, David R. Sibley
Publikováno v: Biomolecules, Vol 13, Iss 10, p 1552 (2023)
The D2 dopamine receptor (D2R) signals through both G proteins and β-arrestins to regulate important physiological processes, such as movement, reward circuitry, emotion, and cognition. β-arrestins are believed to interact with G protein-coupled re
Externí odkaz: https://doaj.org/article/a4efa938f10740ff9782ac55fdd0a957
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3
Delineation of G Protein-Coupled Receptor Kinase Phosphorylation Sites within the D1 Dopamine Receptor and Their Roles in Modulating β-Arrestin Binding and Activation
Autor: Amy E. Moritz, Nora S. Madaras, Michele L. Rankin, Laura R. Inbody, David R. Sibley
Publikováno v: International Journal of Molecular Sciences; Volume 24; Issue 7; Pages: 6599
The D1 dopamine receptor (D1R) is a G protein-coupled receptor that signals through activating adenylyl cyclase and raising intracellular cAMP levels. When activated, the D1R also recruits the scaffolding protein β-arrestin, which promotes receptor
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a72d89a3ef13a6f9958e29d7d181bf20
https://doi.org/10.3390/ijms24076599
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7
Design, synthesis, and biological evaluation of lipophilically modified bisphenol Z derivatives
Autor: P.S.S. Rao, Richard Dudley, Laura R. Inbody, Ryan A. Schneider, Christopher R.T. Stang, Lea M. Stitzlein
Publikováno v: Chemical Biology & Drug Design.
In the present study, a small library of bisphenol Z (BPZ) derivatives was synthesized and investigated for anti-proliferative effects in cultured breast and glioblastoma cell lines. Synthesized BPZ derivatives varied in molecular size, polarity, and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a96b45359931a9be9350fdadb6a9d6a
https://doi.org/10.1111/cbdd.13531
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Plný text Recenzováno Digitální knihovna AV ČR
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