Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Laura Prochazka"'
Autor:
Chris Bond, Valerie Wall, Siddarth Chandrasekaran, Melanie Kardel, Elisa Martinez, Nabil Zeidan, Avisek Deyati, Dylan Lee, Negin Farahani, Amanda AuYeung, Omar Subedar, Michael Cadell, Sommer Apelu, Laura Prochazka, Zahra Sahaf, Angela Duong, Cole Zmurchok, Boyoung Yoon, Dan Kirouac, Muluken Belew, Jasdeep Mann, Deepika Rajesh
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/2c17e535765943d18444098d59b7f386
Autor:
Laura Prochazka, Yale S Michaels, Charles Lau, Ross D Jones, Mona Siu, Ting Yin, Diana Wu, Esther Jang, Mercedes Vázquez‐Cantú, Penney M Gilbert, Himanshu Kaul, Yaakov Benenson, Peter W Zandstra
Publikováno v:
Molecular Systems Biology, Vol 18, Iss 11, Pp n/a-n/a (2022)
Abstract During development, cell state transitions are coordinated through changes in the identity of molecular regulators in a cell type‐ and dose‐specific manner. The ability to rationally engineer such transitions in human pluripotent stem ce
Externí odkaz:
https://doaj.org/article/e2b62297353c4d7b84600c9edd7e25df
Autor:
Dominika Dziedzicka, Mukul Tewary, Alexander Keller, Laurentijn Tilleman, Laura Prochazka, Joel Östblom, Edouard Couvreu De Deckersberg, Christina Markouli, Silvie Franck, Filip Van Nieuwerburgh, Claudia Spits, Peter W. Zandstra, Karen Sermon, Mieke Geens
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Low differentiation propensity towards a targeted lineage can significantly hamper the utility of individual human pluripotent stem cell (hPSC) lines in biomedical applications. Here, we use monolayer and micropatterned cell cultures, as wel
Externí odkaz:
https://doaj.org/article/9e385811ab3744d7a6a8dfcfa4c06319
Autor:
Mukul Tewary, Dominika Dziedzicka, Joel Ostblom, Laura Prochazka, Nika Shakiba, Tiam Heydari, Daniel Aguilar-Hidalgo, Curtis Woodford, Elia Piccinini, David Becerra-Alonso, Alice Vickers, Blaise Louis, Nafees Rahman, Davide Danovi, Mieke Geens, Fiona M Watt, Peter W Zandstra
Publikováno v:
PLoS Biology, Vol 17, Iss 10, p e3000081 (2019)
In vitro models of postimplantation human development are valuable to the fields of regenerative medicine and developmental biology. Here, we report characterization of a robust in vitro platform that enabled high-content screening of multiple human
Externí odkaz:
https://doaj.org/article/3d54779845f24e319469e56edbe389d3
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Progress in drug discovery can be hampered by a limited exploration of chemical space and the difficulty in assessing the full range of drug candidates’ effects on living cells. Here the authors describe a cell-based assay to distinguish between of
Externí odkaz:
https://doaj.org/article/65aee4710469475e974f5ac63c44d69a
Autor:
Silvie Franck, Claudia Spits, Mukul Tewary, Mieke Geens, Karen Sermon, Joel Ostblom, Edouard Couvreu De Deckersberg, Laurentijn Tilleman, Dominika Dziedzicka, Laura Prochazka, Filip Van Nieuwerburgh, Alexander S. Keller, Christina Markouli, Peter W. Zandstra
Publikováno v:
SCIENTIFIC REPORTS
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Low differentiation propensity towards a targeted lineage can significantly hamper the utility of individual human pluripotent stem cell (hPSC) lines in biomedical applications. Here, we use monolayer and micropatterned cell cultures, as well as tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::129ae2a71a5533749e427769bdf100f7
https://hdl.handle.net/1854/LU-8701854
https://hdl.handle.net/1854/LU-8701854
Autor:
Jonathan Kleinert, Laura Prochazka, Linling Shen, Jiten Doshi, Joerg Schreiber, Yaakov Benenson, Margaux Dastor, Bartolomeo Angelici, Ina Klebba
Publikováno v:
ACS Synthetic Biology. 7:474-489
Cell classifier gene circuits that integrate multiple molecular inputs to restrict the expression of therapeutic outputs to cancer cells have the potential to result in efficacious and safe cancer therapies. Preclinical translation of the hitherto de
Autor:
Laura Prochazka, Nika Shakiba, Teresa Zulueta-Coarasa, Rodrigo Fernandez-Gonzalez, Joel Ostblom, Mukul Tewary, Peter W. Zandstra
Publikováno v:
Development (Cambridge, England)
How position-dependent cell fate acquisition occurs during embryogenesis is a central question in developmental biology. To study this process, we developed a defined, high-throughput assay to induce peri-gastrulation-associated patterning in geometr
Autor:
Nafees Rahman, Fiona M. Watt, Alice Vickers, Davide Danovi, Nika Shakiba, Daniel Aguilar-Hidalgo, Dominika Dziedzicka, Laura Prochazka, Tiam Heydari, Mieke Geens, David Becerra-Alonso, Curtis Woodford, Mukul Tewary, Elia Piccinini, Joel Ostblom, Peter W. Zandstra, Blaise Louis
Publikováno v:
PLoS Biology, Vol 17, Iss 10, p e3000081 (2019)
PLoS Biology
PLoS Biology
In vitro models of postimplantation human development are valuable to the fields of regenerative medicine and developmental biology. Here, we report characterization of a robust in vitro platform that enabled high-content screening of multiple human
Autor:
Blaise Louis, Curtis Woodford, Alice Vickers, Dominika Dziedzicka, Nafees Rahman, Nika Shakiba, Elia Piccinini, Joel Ostblom, Peter W. Zandstra, Mieke Geens, Laura Prochazka, Mukul Tewary, Davide Danovi, Fiona M. Watt
In vitromodels of post-implantation human development are valuable to the fields of regenerative medicine and developmental biology. Here, we report characterization of a robustin vitroplatform that enabled high-content screening of multiple human pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5568e095ab72a9e223b1302233b2a6d0
https://doi.org/10.1101/465039
https://doi.org/10.1101/465039