Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Laura Petersilie"'
Autor:
Laura Petersilie, Karl W. Kafitz, Louis A. Neu, Sonja Heiduschka, Stephanie Le, Alessandro Prigione, Christine R. Rose
Publikováno v:
STAR Protocols, Vol 5, Iss 3, Pp 103212- (2024)
Summary: Three-dimensional brain organoids from human pluripotent stem cells are a powerful tool for studying human neural networks. Here, we present a protocol for generating cortical brain organoid slices (cBOS) derived from regionalized cortical o
Externí odkaz:
https://doaj.org/article/1b1c2c848704492f8b2e916be127daec
Autor:
Alok Bhattarai, Jan Meyer, Laura Petersilie, Syed I. Shah, Louis A. Neu, Christine R. Rose, Ghanim Ullah
Publikováno v:
Biomolecules, Vol 14, Iss 11, p 1348 (2024)
With the recent surge in the development of highly selective probes, fluorescence microscopy has become one of the most widely used approaches to studying cellular properties and signaling in living cells and tissues. Traditionally, microscopy image
Externí odkaz:
https://doaj.org/article/20481e4f24a44d3fbc7f586ad5074659
Autor:
Laura Petersilie, Sonja Heiduschka, Joel S.E. Nelson, Louis A. Neu, Stephanie Le, Ruchika Anand, Karl W. Kafitz, Alessandro Prigione, Christine R. Rose
Publikováno v:
iScience, Vol 27, Iss 4, Pp 109415- (2024)
Summary: Brain organoids derived from human pluripotent stem cells are a promising tool for studying human neurodevelopment and related disorders. Here, we generated long-term cultures of cortical brain organoid slices (cBOS) grown at the air-liquid
Externí odkaz:
https://doaj.org/article/f83e373fe09e4483942951f1ce28e66a
Autor:
Carmen Menacho, Satoshi Okawa, Laura Petersilie, Annette Seibt, Markus Schülke, Felix Distelmaier, Christine R. Rose, Antonio Del Sol, Alessandro Prigione
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S188- (2023)
Externí odkaz:
https://doaj.org/article/c5f67a05b81945489eb9f13d3e3acc3b
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Astrocytic gap junctional coupling is a major element in neuron–glia interaction. There is strong evidence that impaired coupling is involved in neurological disorders. Reduced coupling was, e.g., demonstrated for core regions of ischemic stroke th
Externí odkaz:
https://doaj.org/article/4e5bf3b9759f4c56a5cb68ca86514d43
Autor:
Miriam Engels, Manu Kalia, Sarah Rahmati, Laura Petersilie, Peter Kovermann, Michel J. A. M. van Putten, Christine R. Rose, Hil G. E. Meijer, Thomas Gensch, Christoph Fahlke
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
High water permeabilities permit rapid adjustments of glial volume upon changes in external and internal osmolarity, and pathologically altered intracellular chloride concentrations ([Cl–]int) and glial cell swelling are often assumed to represent
Externí odkaz:
https://doaj.org/article/e4dd397a81b24c9dae7d214e33363205
Autor:
Manu Kalia, Christine R. Rose, Laura Petersilie, Sarah Rahmati, Peter Kovermann, Michel J.A.M. van Putten, Miriam Engels, Thomas Gensch, Christoph Fahlke, Hil Gaétan Ellart Meijer
Publikováno v:
Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Frontiers in cellular neuroscience 15, 735300 (2021). doi:10.3389/fncel.2021.735300
Frontiers in cellular neuroscience, 15:735300. Frontiers Research Foundation
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Frontiers in cellular neuroscience 15, 735300 (2021). doi:10.3389/fncel.2021.735300
Frontiers in cellular neuroscience, 15:735300. Frontiers Research Foundation
High water permeabilities permit rapid adjustments of glial volume upon changes in external and internal osmolarity, and pathologically altered intracellular chloride concentrations ([Cl–]int) and glial cell swelling are often assumed to represent
Autor:
Agnieszka Rybak-Wolf, Gizem Inak, Nikolaus Rajewsky, Carmen Menacho-Pando, Stephanie Le, Karl W. Kafitz, Christine R. Rose, Alessandro Prigione, Laura Petersilie
Publikováno v:
Journal of Visualized Experiments.
Mitochondrial diseases represent the largest class of inborn errors of metabolism and are currently incurable. These diseases cause neurodevelopmental defects whose underlying mechanisms remain to be elucidated. A major roadblock is the lack of effec
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 19
International Journal of Molecular Sciences, Vol 21, Iss 7376, p 7376 (2020)
Volume 21
Issue 19
International Journal of Molecular Sciences, Vol 21, Iss 7376, p 7376 (2020)
Anisotropic gap junctional coupling is a distinct feature of astrocytes in many brain regions. In the lateral superior olive (LSO), astrocytic networks are anisotropic and oriented orthogonally to the tonotopic axis. In CaV1.3 knock-out (KO) and otof
Autor:
Aldo R. Boccaccini, Clemens M Sauter, Julia Kapr, Ellen Fritsche, Ines Lauria, Laura Petersilie, Farina Bendt, Christine R. Rose, Thomas Distler
Publikováno v:
Advanced Healthcare Materials. 10:2100131
Stable and predictive neural cell culture models are a necessary premise for many research fields. However, conventional 2D models lack 3D cell-material/-cell interactions and hence do not reflect the complexity of the in vivo situation properly. Her