Super-resolution microscopy reveals majorly mono- and dimeric presenilin1/γ-secretase at the cell surface

Autor: Abril Angélica Escamilla-Ayala, Ragna Sannerud, Magali Mondin, Karin Poersch, Wendy Vermeire, Laura Paparelli, Caroline Berlage, Marcelle Koenig, Lucia Chavez-Gutierrez, Maximilian H Ulbrich, Sebastian Munck, Hideaki Mizuno, Wim Annaert

Publikováno v: eLife, Vol 9 (2020)

γ-Secretase is a multi-subunit enzyme whose aberrant activity is associated with Alzheimer’s disease and cancer. While its structure is atomically resolved, γ-secretase localization in the membrane in situ relies mostly on biochemical data. Here,

Externí odkaz: https://doaj.org/article/a670ba027c4a475a924b0ed9c1d6e874

Super-resolution microscopy reveals majorly mono- and dimeric presenilin1/gamma-secretase at the cell surface

Autor: Wendy Vermeire, Magali Mondin, Sebastian Munck, Hideaki Mizuno, Maximilian H. Ulbrich, Abril Escamilla-Ayala, Karin Poersch, Lucía Chávez-Gutiérrez, Ragna Sannerud, Wim Annaert, Laura Paparelli, Caroline Berlage, Marcelle Koenig

Publikováno v: eLife, Vol 9 (2020)
eLife

γ-Secretase is a multi-subunit enzyme whose aberrant activity is associated with Alzheimer's disease and cancer. While its structure is atomically resolved, γ-secretase localization in the membrane in situ relies mostly on biochemical data. Here, w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb60eef94cd0993f27e9cab1d10b8b1a
https://lirias.kuleuven.be/handle/123456789/663411

Photoionization and Electron Radical Recombination Dynamics in Photoactive Yellow Protein Investigated by Ultrafast Spectroscopy in the Visible and Near-Infrared Spectral Region

Autor: Marie Louise Groot, Klaas J. Hellingwerf, Jingyi Zhu, John T. M. Kennis, Ivo H. M. van Stokkum, Laura Paparelli, Jos C. Arents, Marijke Hospes

Publikováno v: Zhu, J, Hospes, M, Arents, J, Kennis, J T M, van Stokkum, I H M, Hellingwerf, K J & Groot, M L 2013, ' Photoionization and Electron Radical Recombination Dynamics in Photoactive Yellow Protein Investigated by Ultrafast Spectroscopy in the Visible and Near-Infrared Spectral Region ', Journal of Physical Chemistry B, vol. 117, no. 38, pp. 11042-11048 . https://doi.org/10.1021/jp311906f
Journal of Physical Chemistry B, 117(38), 11042-11048. American Chemical Society
The journal of Physical Chemistry. B, 117(38), 11042-11048. American Chemical Society

Photoinduced ionization of the chromophore inside photoactive yellow protein (PYP) was investigated by ultrafast spectroscopy in the visible and near-infrared spectral regions. An absorption band that extended from around 550 to 850 nm was observed a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a849e2eac276dda6b3d60c19e52f13b8
https://doi.org/10.1021/jp311906f

Analyzing Protein Clusters on the Plasma Membrane: Application of Spatial Statistical Analysis Methods on Super-Resolution Microscopy Images

Autor: Nikky Corthout, Wim Annaert, Sebastian Munck, Laura Paparelli, Benjamin Pavie

Publikováno v: Focus on Bio-Image Informatics ISBN: 9783319285474

The spatial distribution of proteins within the cell affects their capability to interact with other molecules and directly influences cellular processes and signaling. At the plasma membrane, multiple factors drive protein compartmentalization into

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::86190586bfd8b86292b09007f302e2c6
https://doi.org/10.1007/978-3-319-28549-8_4

Correction to 'Photoionization and Electron Radical Recombination Dynamics in Photoactive Yellow Protein Investigated by Ultrafast Spectroscopy in the Visible and Near-Infrared Spectral Region'

Autor: Jingyi Zhu, Laura Paparelli, Marijke Hospes, Jos Arents, John T. M. Kennis, Ivo H. M. van Stokkum, Klaas J. Hellingwerf, Marie Louise Groot

Publikováno v: The Journal of Physical Chemistry B. 117:13723-13723

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0487f6d43b0b818e9d31b8480d0beb08
https://doi.org/10.1021/jp409999w