Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Laura P M H de Rooij"'
Autor:
Vincent Geldhof, Laura P. M. H. de Rooij, Liliana Sokol, Jacob Amersfoort, Maxim De Schepper, Katerina Rohlenova, Griet Hoste, Adriaan Vanderstichele, Anne-Marie Delsupehe, Edoardo Isnaldi, Naima Dai, Federico Taverna, Shawez Khan, Anh-Co K. Truong, Laure-Anne Teuwen, François Richard, Lucas Treps, Ann Smeets, Ines Nevelsteen, Birgit Weynand, Stefan Vinckier, Luc Schoonjans, Joanna Kalucka, Christine Desmedt, Patrick Neven, Massimiliano Mazzone, Giuseppe Floris, Kevin Punie, Mieke Dewerchin, Guy Eelen, Hans Wildiers, Xuri Li, Yonglun Luo, Peter Carmeliet
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Tumor blood vessels contribute to cancer growth, invasion and metastasis. Here, by using single cell transcriptomics, the authors report an inventory of endothelial cell heterogeneity in patients with breast cancer, including a subtype that expresses
Externí odkaz:
https://doaj.org/article/f607566042124ddc85658b5b9cc9abac
Autor:
Fei Wang, Peiwen Ding, Xue Liang, Xiangning Ding, Camilla Blunk Brandt, Evelina Sjöstedt, Jiacheng Zhu, Saga Bolund, Lijing Zhang, Laura P. M. H. de Rooij, Lihua Luo, Yanan Wei, Wandong Zhao, Zhiyuan Lv, János Haskó, Runchu Li, Qiuyu Qin, Yi Jia, Wendi Wu, Yuting Yuan, Mingyi Pu, Haoyu Wang, Aiping Wu, Lin Xie, Ping Liu, Fang Chen, Jacqueline Herold, Joanna Kalucka, Max Karlsson, Xiuqing Zhang, Rikke Bek Helmig, Linn Fagerberg, Cecilia Lindskog, Fredrik Pontén, Mathias Uhlen, Lars Bolund, Niels Jessen, Hui Jiang, Xun Xu, Huanming Yang, Peter Carmeliet, Jan Mulder, Dongsheng Chen, Lin Lin, Yonglun Luo
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Pigs are important large animal models for biomedical research. Here, the authors construct a single-cell landscape of pig tissues, unravelling the phenotypic heterogeneity of blood endothelial cells in adipose tissues and the evolutionally conserved
Externí odkaz:
https://doaj.org/article/c21d50994fe24c6aa783a0e4f2146142
Autor:
Fei Wang, Peiwen Ding, Xue Liang, Xiangning Ding, Camilla Blunk Brandt, Evelina Sjöstedt, Jiacheng Zhu, Saga Bolund, Lijing Zhang, Laura P. M. H. de Rooij, Lihua Luo, Yanan Wei, Wandong Zhao, Zhiyuan Lv, János Haskó, Runchu Li, Qiuyu Qin, Yi Jia, Wendi Wu, Yuting Yuan, Mingyi Pu, Haoyu Wang, Aiping Wu, Lin Xie, Ping Liu, Fang Chen, Jacqueline Herold, Joanna Kalucka, Max Karlsson, Xiuqing Zhang, Rikke Bek Helmig, Linn Fagerberg, Cecilia Lindskog, Fredrik Pontén, Mathias Uhlen, Lars Bolund, Niels Jessen, Hui Jiang, Xun Xu, Huanming Yang, Peter Carmeliet, Jan Mulder, Dongsheng Chen, Lin Lin, Yonglun Luo
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-2 (2022)
Externí odkaz:
https://doaj.org/article/d4cf4c7a7e6b438db4f2246d1eed4075
Autor:
Lisa M Becker, Shiau-Haln Chen, Julie Rodor, Laura P M H de Rooij, Andrew H Baker, Peter Carmeliet
Publikováno v:
Becker, L M, Chen, S-H, Rodor, J, de Rooij, L P M H, Baker, A H & Carmeliet, P 2022, ' Deciphering endothelial heterogeneity in health and disease at single cell resolution: progress and perspectives ', Cardiovascular Research . https://doi.org/10.1093/cvr/cvac018
Becker, L M, Chen, S H, Rodor, J, de Rooij, L P M H, Baker, A H & Carmeliet, P 2023, ' Deciphering endothelial heterogeneity in health and disease at single-cell resolution : progress and perspectives ', Cardiovascular Research, vol. 119, no. 1, pp. 6-27 . https://doi.org/10.1093/cvr/cvac018
CARDIOVASCULAR RESEARCH
Becker, L M, Chen, S H, Rodor, J, de Rooij, L P M H, Baker, A H & Carmeliet, P 2023, ' Deciphering endothelial heterogeneity in health and disease at single-cell resolution : progress and perspectives ', Cardiovascular Research, vol. 119, no. 1, pp. 6-27 . https://doi.org/10.1093/cvr/cvac018
CARDIOVASCULAR RESEARCH
Endothelial cells (ECs) constitute the inner lining of vascular beds in mammals and are crucial for homeostatic regulation of blood vessel physiology, but also play a key role in pathogenesis of many diseases, thereby representing realistic therapeut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d520683b861c549b627332bacd7568d2
https://pubmed.ncbi.nlm.nih.gov/35179567
https://pubmed.ncbi.nlm.nih.gov/35179567
Autor:
Vincent Geldhof, Laura P. M. H. de Rooij, Liliana Sokol, Jacob Amersfoort, Maxim De Schepper, Katerina Rohlenova, Griet Hoste, Adriaan Vanderstichele, Anne-Marie Delsupehe, Edoardo Isnaldi, Naima Dai, Federico Taverna, Shawez Khan, Anh-Co K. Truong, Laure-Anne Teuwen, François Richard, Lucas Treps, Ann Smeets, Ines Nevelsteen, Birgit Weynand, Stefan Vinckier, Luc Schoonjans, Joanna Kalucka, Christine Desmedt, Patrick Neven, Massimiliano Mazzone, Giuseppe Floris, Kevin Punie, Mieke Dewerchin, Guy Eelen, Hans Wildiers, Xuri Li, Yonglun Luo, Peter Carmeliet
Publikováno v:
Geldhof, V, de Rooij, L P M H, Sokol, L, Amersfoort, J, De Schepper, M, Rohlenova, K, Hoste, G, Vanderstichele, A, Delsupehe, A-M, Isnaldi, E, Dai, N, Taverna, F, Khan, S, Truong, A-C K, Teuwen, L-A, Richard, F, Treps, L, Smeets, A, Nevelsteen, I, Weynand, B, Vinckier, S, Schoonjans, L, Kalucka, J, Desmedt, C, Neven, P, Mazzone, M, Floris, G, Punie, K, Dewerchin, M, Eelen, G, Wildiers, H, Li, X, Luo, Y & Carmeliet, P 2022, ' Single cell atlas identifies lipid-processing and immunomodulatory endothelial cells in healthy and malignant breast ', Nature Communications, vol. 13, no. 1, pp. 5511 . https://doi.org/10.1038/s41467-022-33052-y
Nature communications
Geldhof, V, de Rooij, L P M H, Sokol, L, Amersfoort, J, De Schepper, M, Rohlenova, K, Hoste, G, Vanderstichele, A, Delsupehe, A M, Isnaldi, E, Dai, N, Taverna, F, Khan, S, Truong, A C K, Teuwen, L A, Richard, F, Treps, L, Smeets, A, Nevelsteen, I, Weynand, B, Vinckier, S, Schoonjans, L, Kalucka, J, Desmedt, C, Neven, P, Mazzone, M, Floris, G, Punie, K, Dewerchin, M, Eelen, G, Wildiers, H, Li, X, Luo, Y & Carmeliet, P 2022, ' Single cell atlas identifies lipid-processing and immunomodulatory endothelial cells in healthy and malignant breast ', Nature Communications, vol. 13, 5511 . https://doi.org/10.1038/s41467-022-33052-y
Nature communications
Geldhof, V, de Rooij, L P M H, Sokol, L, Amersfoort, J, De Schepper, M, Rohlenova, K, Hoste, G, Vanderstichele, A, Delsupehe, A M, Isnaldi, E, Dai, N, Taverna, F, Khan, S, Truong, A C K, Teuwen, L A, Richard, F, Treps, L, Smeets, A, Nevelsteen, I, Weynand, B, Vinckier, S, Schoonjans, L, Kalucka, J, Desmedt, C, Neven, P, Mazzone, M, Floris, G, Punie, K, Dewerchin, M, Eelen, G, Wildiers, H, Li, X, Luo, Y & Carmeliet, P 2022, ' Single cell atlas identifies lipid-processing and immunomodulatory endothelial cells in healthy and malignant breast ', Nature Communications, vol. 13, 5511 . https://doi.org/10.1038/s41467-022-33052-y
Since a detailed inventory of endothelial cell (EC) heterogeneity in breast cancer (BC) is lacking, here we perform single cell RNA-sequencing of 26,515 cells (including 8433 ECs) from 9 BC patients and compare them to published EC taxonomies from lu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d770facb3d58d1eaa7504f050d74bd0
https://pubmed.ncbi.nlm.nih.gov/36127427
https://pubmed.ncbi.nlm.nih.gov/36127427
Autor:
Ronald van Leersum, Joan H. de Jong, Hans M. Rodermond, Marnix Jansen, Jurriaan B. Tuynman, Maarten F. Bijlsma, Evelien Dekker, Felipe De Sousa E Melo, Maartje van der Heijden, Xin Wang, Louis Vermeulen, Jan Paul Medema, Carel J. M. van Noesel, Laura P M H de Rooij, Anne Trinh, Florian Markowetz, Evelyn Fessler, Onno J. de Boer
Publikováno v:
Nature medicine, 19(5), 614-618. Nature Publishing Group
Colon cancer is a clinically diverse disease. This heterogeneity makes it difficult to determine which patients will benefit most from adjuvant therapy and impedes the development of new targeted agents. More insight into the biological diversity of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52fc37bcc218e43caa84e665943b65fe
https://doi.org/10.1038/nm.3174
https://doi.org/10.1038/nm.3174