Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Laura Pătraș"'
Autor:
Nadia Houerbi, JangKeun Kim, Eliah G. Overbey, Richa Batra, Annalise Schweickart, Laura Patras, Serena Lucotti, Krista A. Ryon, Deena Najjar, Cem Meydan, Namita Damle, Christopher Chin, S. Anand Narayanan, Joseph W. Guarnieri, Gabrielle Widjaja, Afshin Beheshti, Gabriel Tobias, Fanny Vatter, Jeremy Wain Hirschberg, Ashley Kleinman, Evan E. Afshin, Matthew MacKay, Qiuying Chen, Dawson Miller, Aaron S. Gajadhar, Lucy Williamson, Purvi Tandel, Qiu Yang, Jessica Chu, Ryan Benz, Asim Siddiqui, Daniel Hornburg, Steven Gross, Bader Shirah, Jan Krumsiek, Jaime Mateus, Xiao Mao, Irina Matei, Christopher E. Mason
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract As spaceflight becomes more common with commercial crews, blood-based measures of crew health can guide both astronaut biomedicine and countermeasures. By profiling plasma proteins, metabolites, and extracellular vesicles/particles (EVPs) fr
Externí odkaz:
https://doaj.org/article/247c896f001a435c9ecc55bb10c04051
Autor:
Eliah G. Overbey, Krista Ryon, JangKeun Kim, Braden T. Tierney, Remi Klotz, Veronica Ortiz, Sean Mullane, Julian C. Schmidt, Matthew MacKay, Namita Damle, Deena Najjar, Irina Matei, Laura Patras, J. Sebastian Garcia Medina, Ashley S. Kleinman, Jeremy Wain Hirschberg, Jacqueline Proszynski, S. Anand Narayanan, Caleb M. Schmidt, Evan E. Afshin, Lucinda Innes, Mateo Mejia Saldarriaga, Michael A. Schmidt, Richard D. Granstein, Bader Shirah, Min Yu, David Lyden, Jaime Mateus, Christopher E. Mason
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract The SpaceX Inspiration4 mission provided a unique opportunity to study the impact of spaceflight on the human body. Biospecimen samples were collected from four crew members longitudinally before (Launch: L-92, L-44, L-3 days), during (Fligh
Externí odkaz:
https://doaj.org/article/b22dea1eff964fe5b8f65b60bc282674
Autor:
Attila Marton, Csongor I. Vágási, Orsolya Vincze, Veronika Bókony, Péter L. Pap, Laura Pătraș, Janka Pénzes, Lőrinc Bărbos, Attila Fülöp, Gergely Osváth, Simon Ducatez, Mathieu Giraudeau
Publikováno v:
Ecology and Evolution, Vol 12, Iss 8, Pp n/a-n/a (2022)
Abstract The mechanistic link between avian oxidative physiology and plumage coloration has attracted considerable attention in past decades. Hence, multiple proximal hypotheses were proposed to explain how oxidative state might covary with the produ
Externí odkaz:
https://doaj.org/article/07a3660f640547a392f3a7f47820698e
Autor:
Csongor I Vágási, Laura Pătraș, Péter L Pap, Orsolya Vincze, Cosmin Mureșan, József Németh, Ádám Z Lendvai
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0192701 (2018)
Glucocorticoid (GC) hormones are significant regulators of homeostasis. The physiological effects of GCs critically depend on the time of exposure (short vs. long) as well as on their circulating levels (baseline vs. stress-induced). Previous experim
Externí odkaz:
https://doaj.org/article/a94a7ae0df664b1abe78644b30ab6197
Autor:
Doriana-Mădălina Buda, Mihaela Ileana Ionescu, Lucian Barbu-Tudoran, Horia L. Banciu, Alina Porfire, Alina Sesarman, Septimiu Tripon, Marin Șenilă, Paul-Adrian Bulzu, Laura Pătraș
Publikováno v:
FEMS Microbiology Letters. 366
Adaptive strategies responsible for heavy metal tolerance were explored in the extremely halophilic archaeon Halomicrobium mukohataei DSM 12286. The tested strain was seemingly able to overcome silver-induced oxidative stress (assessed by malondialde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::138c80ebe869af00296116d32cb0142c
https://doi.org/10.1093/femsle/fnz231
https://doi.org/10.1093/femsle/fnz231
Autor:
Gergely Osváth, Zoltán Barta, Mark F. Haussmann, Csongor I. Vágási, Janka Pénzes, Orsolya Vincze, Laura Pătraș, Péter L. Pap
Publikováno v:
Funct Ecol
1. The mechanisms that underpin the evolution of ageing and life histories remain elusive. Oxidative stress, which results in accumulated cellular damages, is one of the mechanisms suggested to play a role. 2. In this paper, we set out to test the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38768688cd618cd4c39c1c6fb369f435
https://europepmc.org/articles/PMC8291348/
https://europepmc.org/articles/PMC8291348/
Autor:
Péter L. Pap, Orsolya Vincze, Laura Pătraș, Janka Pénzes, Csongor I. Vágási, Attila Fülöp, Orsolya Székely-Béres
Organisms face resource trade-offs to support their parental effort and survival. The life-history oxidative stress hypothesis predicts that an individual’s redox state modulates the trade-off between current and residual fitness, but this has seld
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d19c6842ec6228e7e78659ecba89604
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
The discovery that primary tumors condition distant organ sites of future metastasis for seeding by disseminating tumor cells through a process described as the pre-metastatic niche (PMN) formation revolutionized our understanding of cancer progressi
Externí odkaz:
https://doaj.org/article/df151905edbe49d49364b2ad82d44960
Autor:
Valentin-Florian Rauca, Laura Patras, Lavinia Luput, Emilia Licarete, Vlad-Alexandru Toma, Alina Porfire, Augustin Catalin Mot, Elena Rakosy-Tican, Alina Sesarman, Manuela Banciu
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Anti-angiogenic therapies for melanoma have not yet been translated into meaningful clinical benefit for patients, due to the development of drug-induced resistance in cancer cells, mainly caused by hypoxia-inducible factor 1α (HIF-1α) ove
Externí odkaz:
https://doaj.org/article/03c6b0e8b4f24848a334855428de8d78
Autor:
Giorgiana Negrea, Valentin-Florian Rauca, Marta Szilvia Meszaros, Laura Patras, Lavinia Luput, Emilia Licarete, Vlad-Alexandru Toma, Alina Porfire, Dana Muntean, Alina Sesarman, Manuela Banciu
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Primary melanoma aggressiveness is determined by rapid selection and growth of cellular clones resistant to conventional treatments, resulting in metastasis and recurrence. In addition, a reprogrammed tumor-immune microenvironment supports melanoma p
Externí odkaz:
https://doaj.org/article/8b0acd811112429abc5b0a7d281a4fb3