Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Laura Muzzolini"'
Autor:
Laura Muzzolini, Fabienne Beuron, Ardan Patwardhan, Venkateswarlu Popuri, Sheng Cui, Benedetta Niccolini, Mathieu Rappas, Paul S Freemont, Alessandro Vindigni
Publikováno v:
PLoS Biology, Vol 5, Iss 2, p e20 (2007)
RecQ helicases are essential for the maintenance of chromosome stability. In addition to DNA unwinding, some RecQ enzymes have an intrinsic DNA strand annealing activity. The function of this dual enzymatic activity and the mechanism that regulates i
Externí odkaz:
https://doaj.org/article/f6fc8feed45645e59e75881fe6900f44
Autor:
Silvia Costantini, Csanád Z. Bachrati, Alessandro Vindigni, Georgina Mosedale, Elisa Giacomini, Ian D. Hickson, Venkateswarlu Popuri, Laura Muzzolini
Publikováno v:
Journal of Biological Chemistry. 283:17766-17776
RecQ helicases maintain chromosome stability by resolving a number of highly specific DNA structures that would otherwise impede the correct transmission of genetic information. Previous studies have shown that two human RecQ helicases, BLM and WRN,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20b998d105783546a0df5d75994170ee
https://doi.org/10.1074/jbc.m709749200
https://doi.org/10.1074/jbc.m709749200
Publikováno v:
Biochemistry. 45:773-782
Nucleoside hydrolases (NHs) are enzymes that catalyze the excision of the N-glycosidic bond in nucleosides to allow recycling of the nitrogenous bases. The fine details of the catalytic mechanism and the structural features imposing the substrate spe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa7845bbb8cdf5b697081e9dabcde467
https://doi.org/10.1021/bi0511991
https://doi.org/10.1021/bi0511991
Autor:
Paola Tornaghi, David W. Parkin, An Vandemeulebroucke, Ilaria Bruno, Jan Steyaert, Claudia Minici, Laura Muzzolini, Massimo Degano, Wim Versées
Publikováno v:
Biochemistry. 49(41)
Trypanosomes are purine-auxotrophic parasites that depend upon nucleoside hydrolase (NH) activity to salvage nitrogenous bases necessary for nucleic acid and cofactor synthesis. Nonspecific and purine-specific NHs have been widely studied, yet little
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f945c310ce10798e5062805fa3ce9cd5
https://pubmed.ncbi.nlm.nih.gov/20825170
https://pubmed.ncbi.nlm.nih.gov/20825170
Publikováno v:
BMC Structural Biology, Vol 10, Iss 1, p 14 (2010)
BMC Structural Biology
BMC Structural Biology
Background Pyrimidine-preferring N-ribohydrolases (CU-NHs) are a class of Ca2+-dependent enzymes that catalyze the hydrolytic cleavage of the N-glycosidic bond in pyrimidine nucleosides. With the exception of few selected organisms, their physiologic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a142eecd2c7fca2488b74ac371755b8
http://www.biomedcentral.com/1472-6807/10/14
http://www.biomedcentral.com/1472-6807/10/14
Autor:
Binesh Shrestha, Opher Gileadi, Laura Muzzolini, N.A. Burgess-Brown, Silvia Costantini, Alessandro Vindigni, Ashley C. W. Pike, Venkateswarlu Popuri
RecQ-like helicases, which include 5 members in the human genome, are important in maintaining genome integrity. We present a crystal structure of a truncated form of the human RECQ1 protein with Mg-ADP. The truncated protein is active in DNA fork un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9f5aed8b7048b453e63190aef4b456b
https://europepmc.org/articles/PMC2628305/
https://europepmc.org/articles/PMC2628305/
Autor:
Elena Iovane, Massimo Degano, Barbara Giabbai, Vittoria Matafora, Arianna Fornili, Laura Muzzolini, Francesca Giannese, Claudia Minici
Enzymes with nucleoside hydrolase activity (NHs) belonging to homology group I either are markedly specific for pyrimidine nucleoside substrates or hydrolyze with comparable efficiencies the N-glycosidic bond in all common nucleosides. The biochemica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::856f404e3cd2ae4e3f88f19ed5378bfe
http://hdl.handle.net/2318/142545
http://hdl.handle.net/2318/142545
Autor:
Sheng Cui, Alessandro Vindigni, Joshua A. Sommers, Robert M. Brosh, Laura Muzzolini, Saba Choudhary, Jinnifer Korin Faulkner, Lucia Andreoli, Sudha Sharma
Publikováno v:
The Journal of biological chemistry. 280(30)
RecQ helicases play an important role in preserving genomic integrity, and their cellular roles in DNA repair, recombination, and replication have been of considerable interest. Of the five human RecQ helicases identified, three are associated with g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70eca4cde8971089386d36382f909e5f
https://pubmed.ncbi.nlm.nih.gov/15899892
https://pubmed.ncbi.nlm.nih.gov/15899892
Publikováno v:
European journal of cell biology. 82(1)
Summary We have studied the intracellular localization of annexins I, II, VI, VII, and XI in cells containing latex beads or Mycobacterium avium at different times after ingestion in order to establish whether a correlation existed between the associ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7681d725a050b4abbee98972ecb3e48
https://pubmed.ncbi.nlm.nih.gov/12602944
https://pubmed.ncbi.nlm.nih.gov/12602944
Publikováno v:
Acta Crystallographica Section A Foundations of Crystallography. 60:s152-s152
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9cd39871e2c5675a642507a018a01792
https://doi.org/10.1107/s0108767304097004
https://doi.org/10.1107/s0108767304097004