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pro vyhledávání: '"Laura Miranda Pinheiro"'
Autor:
Luiz Augusto Basso, Kenia Pissinate, Dharmarajan Sriram, Perumal Yogeeswari, Diógenes Santiago Santos, Diana C. Rostirolla, Pablo Machado, Priyanka Suryadevara, Laura Miranda Pinheiro
Publikováno v:
Journal of the Brazilian Chemical Society.
Using an orthologue-based design approach, we synthesized and assayed a series of thiazolyl-1H-benzo[d]imidazole derivatives as inhibitors of Mycobacterium tuberculosis inosine 5'-monophosphate dehydrogenase (MtIMPDH). From these experiments, a benzo