Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Laura Minsaas"'
Autor:
Oleksii Nikolaienko, Hans P. Eikesdal, Elisabet Ognedal, Bjørnar Gilje, Steinar Lundgren, Egil S. Blix, Helge Espelid, Jürgen Geisler, Stephanie Geisler, Emiel A. M. Janssen, Synnøve Yndestad, Laura Minsaas, Beryl Leirvaag, Reidun Lillestøl, Stian Knappskog, Per E. Lønning
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-15 (2023)
Abstract Background Normal cell BRCA1 epimutations have been associated with increased risk of triple-negative breast cancer (TNBC). However, the fraction of TNBCs that may have BRCA1 epimutations as their underlying cause is unknown. Neither are the
Externí odkaz:
https://doaj.org/article/0089602380aa46b390f13cb9bbdb281f
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e40864 (2012)
BACKGROUND: Filamin A (FLNa) is an actin-crosslinking protein necessary for stabilizing the cell surface, organizing protrusive activity and for promoting efficient cellular translocation. Recently, our group demonstrated the requirement of FLNa for
Externí odkaz:
https://doaj.org/article/5b19e47bfd244b63a7fd3a5494c5c422
Autor:
Laura Minsaas, Jesús Planagumà, Michael Madziva, Beate F Krakstad, Míriam Masià-Balagué, Arieh A Katz, Anna M Aragay
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12212 (2010)
The chemokine (C-C motif) receptor 2B (CCR2B) is one of the two isoforms of the receptor for monocyte chemoattractant protein-1 (CCL2), the major chemoattractant for monocytes, involved in an array of chronic inflammatory diseases. Employing the yeas
Externí odkaz:
https://doaj.org/article/51341e740e8148a48985d0a652b804d8
Autor:
Christina Engebrethsen, Synnøve Yndestad, Andrea Herencia-Ropero, Oleksii Nikolaienko, Olav Karsten Vintermyr, Reidun K. Lillestøl, Laura Minsaas, Beryl Leirvaag, Gjertrud Iversen, Bjørnar Gilje, Egil Blix, Helge Espelid, Steinar Lundgren, Jürgen Geisler, Liv Jorunn Vassbotn, Hildegunn S. Aase, Turid Aas, Alba Llop-Guevara, Violeta Serra, Per Eystein Lønning, Stian Knappskog, Hans Petter Eikesdal
Publikováno v:
Cancer Research. 83:P6-10
Background: Homologous recombination deficiency (HRD) is highly prevalent in triple-negative breast cancer (TNBC) and predictive of response to PARP inhibition in the primary setting (Eikesdal et al, Ann Oncol, 2021). However, the prevalence of HRD a
Autor:
Oleksii Nikolaienko, Hans P. Eikesdal, Bjørnar Gilje, Steinar Lundgren, Egil S. Blix, Helge Espelid, Jürgen Geisler, Stephanie Geisler, Emiel A.M. Janssen, Synnøve Yndestad, Laura Minsaas, Beryl Leirvaag, Reidun Lillestøl, Stian Knappskog, Per E. Lønning
BackgroundNormal cellBRCA1epimutations have been associated with increased risk of triple-negative breast cancer (TNBC). However, the fraction of TNBCs that may haveBRCA1epimutations as their underlying cause is unknown.MethodsTo address this questio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2190358b63fbbf66a48d7d6bfcc2496
https://doi.org/10.1101/2023.05.14.23289949
https://doi.org/10.1101/2023.05.14.23289949
Autor:
Helge Espelid, Stian Knappskog, Alba Llop-Guevara, Judith Balmaña, Beryl Leirvaag, Jürgen Geisler, Bjørnar Gilje, Laura Minsaas, Asmaa Elzawahry, Steinar Lundgren, Olav Karsten Vintermyr, Egil S. Blix, Per Eystein Lønning, Synnøve Yndestad, Geirfinn Vagstad, Emiel A. M. Janssen, Hildegunn Siv Aase, Andreas Venizelos, Hans Petter Eikesdal, Violeta Serra, Einar Gudlaugsson, Turid Aas
Publikováno v:
Annals of Oncology
Background The antitumor efficacy of PARP inhibitors (PARPi) for breast cancer patients harboring germline BRCA1/2 (gBRCA1/2) mutations is well established. While PARPi monotherapy was ineffective in patients with metastatic triple negative breast ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71c4233c7a23662c06d637156987fe9c
https://hdl.handle.net/10037/20445
https://hdl.handle.net/10037/20445
Autor:
Stian Knappskog, Per Eystein Lønning, Eivind Valen, Zuzana Sichmanova, Deepak Poduval, Laura Minsaas, Elisabet Ognedal, Gjertrud T. Iversen
Publikováno v:
131 (2020)
Clinical Epigenetics
12:131
Clinical Epigenetics
12:131
Background The number of tumor suppressor genes for which germline mutations have been linked to cancer risk is steadily increasing. However, while recent reports have linked constitutional normal tissue promoter methylation of BRCA1 and MLH1 to ovar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cf471c42db2eb69646baebc1db6e703
https://hdl.handle.net/11250/2727569
https://hdl.handle.net/11250/2727569
Autor:
Jesús Planagumà, Georgina Garrido, Lene Elisabeth Myhren, Mònica Pons, Anna M. Aragay, Laura Minsaas
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 8, p e40864 (2012)
Digital.CSIC. Repositorio Institucional del CSIC
instname
PLoS ONE, Vol 7, Iss 8, p e40864 (2012)
Digital.CSIC. Repositorio Institucional del CSIC
instname
This is an open-access article distributed under the terms of the Creative Commons Attribution License.
[Background]: Filamin A (FLNa) is an actin-crosslinking protein necessary for stabilizing the cell surface, organizing protrusive activity an
[Background]: Filamin A (FLNa) is an actin-crosslinking protein necessary for stabilizing the cell surface, organizing protrusive activity an
Autor:
Anja Tveit, Stian Nylund, Litta Olsen, Stian Knappskog, Hanne Ravneberg, Lene C. Olsen, Christine Gjerdrum, Ian F. Pryme, Albert Tauler, Laura Minsaas, John E. Hesketh, Endre Vollsund, Eystein Oveland, Beate Stern, Christiane Trösse
Publikováno v:
Cell Technology for Cell Products ISBN: 9781402054754
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0be29096bd45d6b008e906ba8b6a3526
https://doi.org/10.1007/978-1-4020-5476-1_41
https://doi.org/10.1007/978-1-4020-5476-1_41
Publikováno v:
The FEBS journal. 272(20)
Metabolically unstable proteins are involved in a multitude of regulatory networks, including those that control cell signaling, the cell cycle and in many responses to physiological stress. In the present study, we have determined the stability and