Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Laura Masino"'
Autor:
Sarah J. Young, Marie Sebald, Rajvee Shah Punatar, Meghan Larin, Laura Masino, Monica C. Rodrigo-Brenni, Chih-Chao Liang, Stephen C. West
Publikováno v:
Cell Reports, Vol 33, Iss 3, Pp 108289- (2020)
Summary: MutSα and MutSβ play important roles in DNA mismatch repair and are linked to inheritable cancers and degenerative disorders. Here, we show that MSH2 and MSH3, the two components of MutSβ, bind SLX4 protein, a scaffold for the assembly of
Externí odkaz:
https://doaj.org/article/fcd87da1d9a44e2dbf954e4228e5b795
Autor:
Jamie A Macpherson, Alina Theisen, Laura Masino, Louise Fets, Paul C Driscoll, Vesela Encheva, Ambrosius P Snijders, Stephen R Martin, Jens Kleinjung, Perdita E Barran, Franca Fraternali, Dimitrios Anastasiou
Publikováno v:
eLife, Vol 8 (2019)
Several enzymes can simultaneously interact with multiple intracellular metabolites, however, how the allosteric effects of distinct ligands are integrated to coordinately control enzymatic activity remains poorly understood. We addressed this questi
Externí odkaz:
https://doaj.org/article/e58bac1bbbec4b70ba28e24697d45179
Publikováno v:
Nature Structural & Molecular Biology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::298026719c05fcbc0c4058ab091b55b9
https://doi.org/10.1038/s41594-023-00985-x
https://doi.org/10.1038/s41594-023-00985-x
Autor:
Marc Mora, Stephanie Board, Olivier Languin-Cattoën, Laura Masino, Guillaume Stirnemann, Sergi Garcia-Manyes
Publikováno v:
Nano Letters. 22:3922-3930
Non-native disulfide bonds are dynamic covalent bridges that form post-translationally between two cysteines within the same protein (intramolecular) or with a neighboring protein (intermolecular), frequently due to changes in the cellular redox pote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70745010db9a651db3d306ff7cbd1140
https://doi.org/10.1021/acs.nanolett.2c00043
https://doi.org/10.1021/acs.nanolett.2c00043
Autor:
Danicke Willemse, Brandon Weber, Laura Masino, Robin M Warren, Salvatore Adinolfi, Annalisa Pastore, Monique J Williams
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0200145 (2018)
Iron-sulphur (Fe-S) clusters are ubiquitous co-factors which require multi-protein systems for their synthesis. In Mycobacterium tuberculosis, the Rv1460-Rv1461-Rv1462-Rv1463-csd-Rv1465-Rv1466 operon (suf operon) encodes the primary Fe-S cluster biog
Externí odkaz:
https://doaj.org/article/817f88cd0e8641d594c86fef20b18247
Autor:
Rubika Balendra, Igor Ruiz de los Mozos, Idoia Glaria, Carmelo Milioto, Hana M Odeh, Katherine M Wilson, Agnieszka M Ule, Martina Hallegger, Laura Masino, Stephen Martin, Rickie Patani, James Shorter, Jernej Ule, Adrian M Isaacs
An intronic GGGGCC repeat expansion inC9orf72is a common genetic cause of amyotrophic lateral sclerosis and frontotemporal dementia. The repeats are transcribed in both sense and antisense directions to generate distinct dipeptide repeat proteins, of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7884474e238fa34edd2e211aa5ecae20
https://doi.org/10.1101/2022.10.10.511318
https://doi.org/10.1101/2022.10.10.511318
Autor:
Annalisa Pastore, Laura Masino, Andrea Mattevi, Alessandro Sicorello, Francesca Magnani, Petr Pompach, Sofia Todesca, Elisa Millana Fananas
Publikováno v:
The Febs Journal
It is now accepted that reactive oxygen species (ROS) are not only dangerous oxidative agents but also chemical mediators of the redox cell signaling and innate immune response. A central role in ROS‐controlled production is played by the NADPH oxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddc98ea607c7e9f8900e1af518a068a7
http://europepmc.org/articles/PMC7317449
http://europepmc.org/articles/PMC7317449
Autor:
Luiz Pedro S. de Carvalho, Laura Masino, Holly L. Douglas, Argyrides Argyrou, Jonathan Bailey
Publikováno v:
Biochemistry
Methionine adenosyltransferase (MAT) catalyzes the adenosine 5'-triphosphate (ATP) and l-methionine (l-Met) dependent formation of S-adenosyl-l-methionine (SAM), the principal methyl donor of most biological transmethylation reactions. We carried out
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4d530b5d3b6429df99ebedadedf5e66
https://pubmed.ncbi.nlm.nih.gov/34780697
https://pubmed.ncbi.nlm.nih.gov/34780697
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2263
RNA-binding proteins often contain multiple RNA-binding domains connected by short flexible linkers. This domain arrangement allows the protein to bind the RNA with greater affinity and specificity than would be possible with individual domains and s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3a394f4514a26ed0ee2f5dbddcdcfe10
https://pubmed.ncbi.nlm.nih.gov/33877607
https://pubmed.ncbi.nlm.nih.gov/33877607
Autor:
Tammaryn Lashley, Maria Secrier, Giampietro Schiavo, Pietro Fratta, Hemali Phatnani, Flora C.Y. Lee, Sam Byrce-Smith, Anna-Leigh Brown, Matthew Keuss, Yue Qi, Laura Masino, Sarah C. Hill, Ariana Gatt, Alexander Bampton, Towfique Raj, Michael E. Ward, Elizabeth M. C. Fisher, Jernej Ule, Emanuele Buratti, Jack Humphrey, Oscar G. Wilkins, Weaverly Colleen Lee, Matteo Zanovello
Variants within the UNC13A gene have long been known to increase risk of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), two related neurodegenerative diseases defined by mislocalization of the RNA-binding protein TDP-43. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03cc082bd71ec0a6d80a2e975ee4e60b
https://doi.org/10.21203/rs.3.rs-386600/v1
https://doi.org/10.21203/rs.3.rs-386600/v1