Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Laura Martinson"'
Autor:
Tobias Boettler, Darius Schneider, Yang Cheng, Kuniko Kadoya, Eugene P. Brandon, Laura Martinson, Matthias Von Herrath
Publikováno v:
Cell Transplantation, Vol 25 (2016)
Type 1 diabetes (T1D) is characterized by destruction of glucose-responsive insulin-producing pancreatic β-cells and exhibits immune infiltration of pancreatic islets, where CD8 lymphocytes are most prominent. Curative transplantation of pancreatic
Externí odkaz:
https://doaj.org/article/f7e5ecec02dd4fe9938c3b1a76ca61f6
Autor:
Cornelis R. van der Torren, Bart O. Roep, Arnaud Zaldumbide, Mark Peakman, Gaby Duinkerken, Laura Martinson, Eugene P. Brandon, Geert Stange, Simone H. Brand-Schaaf, Daniel Pipeleers, Evert Kroon
Publikováno v:
Diabetologia
Diabetologia, 60(1), 126-133
Europe PubMed Central
van der Torren, C R, Zaldumbide, A, Duinkerken, G, Brand-Schaaf, S H, Peakman, M, Stangé, G, Martinson, L, Kroon, E, Brandon, E P, Pipeleers, D & Roep, B O 2017, ' Immunogenicity of human embryonic stem cell-derived beta cells ', Diabetologia, vol. 60, no. 1, pp. 126–133 . https://doi.org/10.1007/s00125-016-4125-y
Diabetologia, 60(1), 126-133
Europe PubMed Central
van der Torren, C R, Zaldumbide, A, Duinkerken, G, Brand-Schaaf, S H, Peakman, M, Stangé, G, Martinson, L, Kroon, E, Brandon, E P, Pipeleers, D & Roep, B O 2017, ' Immunogenicity of human embryonic stem cell-derived beta cells ', Diabetologia, vol. 60, no. 1, pp. 126–133 . https://doi.org/10.1007/s00125-016-4125-y
Aims/hypothesis To overcome the donor shortage in the treatment of advanced type 1 diabetes by islet transplantation, human embryonic stem cells (hESCs) show great potential as an unlimited alternative source of beta cells. hESCs may have immune priv
Autor:
Laura Martinson, Yang Cheng, Eugene P. Brandon, Matthias von Herrath, Kuniko Kadoya, Tobias Boettler, Darius A. Schneider
Publikováno v:
Cell Transplantation, Vol 25 (2016)
Type 1 diabetes (T1D) is characterized by destruction of glucose-responsive insulin-producing pancreatic β-cells and exhibits immune infiltration of pancreatic islets, where CD8 lymphocytes are most prominent. Curative transplantation of pancreatic
Autor:
Justine J Cunningham, Mike Richardson, Kuniko Kadoya, Nora G. Smart, Melissa K. Carpenter, Susan Eliazer, Holly Y. Young, Emmanuel E. Baetge, Anne G. Bang, Olivia Kelly, Evert Kroon, Alan D. Agulnick, Laura Martinson, Kevin A. D'Amour
Publikováno v:
Nature Biotechnology. 26:443-452
Development of a cell therapy for diabetes would be greatly aided by a renewable supply of human β-cells. Here we show that pancreatic endoderm derived from human embryonic stem (hES) cells efficiently generates glucose-responsive endocrine cells af
Autor:
Thomas A. Horbett, Laura Martinson, David G. Castner, Buddy D. Ratner, Matthew Scott Wagner, Mingchao Shen
Publikováno v:
Journal of Biomaterials Science, Polymer Edition. 13:367-390
Polyethylene oxide (PEO) surfaces reduce non-specific protein and cell interactions with implanted biomaterials and may improve their biocompatibility. PEO-like polymerized tetraglyme surfaces were made by glow discharge plasma deposition onto fluori
Autor:
Kevin A. D'Amour, Kelly G. Ross, Laura Martinson, Evert Kroon, Mike Richardson, Mark A. Moorman, Melissa K. Carpenter, Traci M Ostertag, Emmanuel E. Baetge, Man Yin Chan, Anne G. Bang, Kuniko Kadoya, Olivia Kelly
Publikováno v:
Nature biotechnology. 29(8)
Using a flow cytometry-based screen of commercial antibodies, we have identified cell-surface markers for the separation of pancreatic cell types derived from human embryonic stem (hES) cells. We show enrichment of pancreatic endoderm cells using CD1
Autor:
Carl Haakmeester, Chad Green, Kuniko Kadoya, Mark A. Moorman, Janice K. Payne, Amanda B. McLean, Laura Martinson, Rosemary M. Cesario, Mike Richardson, Eric S. Sherrer, Evert Kroon, M. Josephine Babin, Justin Kerr, Igor Cepa, Alistair Wilson, Olivia Kelly, Allan J. Robins, Emmanuel E. Baetge, Kevin A. D'Amour, Eugene P. Brandon, Jonathan R. Kelly, Kelly G. Ross, Xuehong Song, Anindita Bhoumik, Anne G. Bang, Thomas C. Schulz, Alan D. Agulnick, Holly Y. Young
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e37004 (2012)
PLoS ONE
PLoS ONE
Development of a human embryonic stem cell (hESC)-based therapy for type 1 diabetes will require the translation of proof-of-principle concepts into a scalable, controlled, and regulated cell manufacturing process. We have previously demonstrated tha