Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Laura Martínez-Escardó"'
Autor:
Aina Calls, Abel Torres‐Espin, Marc Tormo, Laura Martínez‐Escardó, Núria Bonet, Ferran Casals, Xavier Navarro, Víctor J. Yuste, Esther Udina, Jordi Bruna
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 9, Iss 12, Pp 1985-1998 (2022)
Abstract Objectives Peripheral neuropathy is a relevant dose‐limiting adverse event that can affect up to 90% of oncologic patients with colorectal cancer receiving oxaliplatin treatment. The severity of neurotoxicity often leads to dose reduction
Externí odkaz:
https://doaj.org/article/70f71dc3d328466699b425c404d85437
Gossypol Treatment Restores Insufficient Apoptotic Function of DFF40/CAD in Human Glioblastoma Cells
Autor:
Laura Martínez-Escardó, Montse Alemany, María Sánchez-Osuna, Alejandro Sánchez-Chardi, Meritxell Roig-Martínez, Salvio Suárez-García, Daniel Ruiz-Molina, Noemi Vidal, Gerard Plans, Carles Majós, Judit Ribas, María Antonia Baltrons, Jose R. Bayascas, Carlos Barcia, Jordi Bruna, Victor J. Yuste
Publikováno v:
Cancers, Vol 13, Iss 21, p 5579 (2021)
Glioblastoma (GBM) is a highly aggressive brain tumor and almost all patients die because of relapses. GBM-derived cells undergo cell death without nuclear fragmentation upon treatment with different apoptotic agents. Nuclear dismantling determines t
Externí odkaz:
https://doaj.org/article/6413408650f8453789322c010a859186
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 7, p 3453 (2021)
Background: The relevance of the cancer immune cycle in therapy response implies that successful treatment may trigger the exposure or the release of immunogenic signals. Previous results with the preclinical GL261 glioblastoma (GB) showed that combi
Externí odkaz:
https://doaj.org/article/bd41e216887b4ffcb15a89fa80319b03
Autor:
Catherine Cloix, Malviya G, Kirsteen J. Campbell, Laura Martínez-Escardó, Kinch K, Dominik Koessinger, Paul N, Gabriel Ichim, Florian J. Bock, Elmasry Y, Kevin M. Ryan, Jane E. Norman, Jim O'Prey, Katrina Stevenson, Anthony J. Chalmers, Anna L. Koessinger, William Stewart, Colin Nixon, Kevin G. Blyth, Stephen W.G. Tait, Mark R. Jackson
IDH wild-type glioblastoma (GBM) is the most prevalent malignant primary brain tumour in adults. GBM typically has a poor prognosis, mainly due to a lack of effective treatment options leading to tumour persistence or recurrence. Tackling this, we in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7beb81f8995f7f595c7b4985a488d12
https://doi.org/10.1101/2021.06.13.448232
https://doi.org/10.1101/2021.06.13.448232
Autor:
Anna L. Koessinger, Catherine Cloix, Dominik Koessinger, Dieter Henrik Heiland, Florian J. Bock, Karen Strathdee, Kevin Kinch, Laura Martínez-Escardó, Nikki R. Paul, Colin Nixon, Gaurav Malviya, Mark R. Jackson, Kirsteen J. Campbell, Katrina Stevenson, Sandeep Davis, Yassmin Elmasry, Asma Ahmed, Jim O’Prey, Gabriel Ichim, Oliver Schnell, William Stewart, Karen Blyth, Kevin M. Ryan, Anthony J. Chalmers, Jim C. Norman, Stephen W. G. Tait
Publikováno v:
Cell Death and Differentiation
Cell Death and Differentiation, 2022, 29 (10), pp.2089-2104. ⟨10.1038/s41418-022-01001-3⟩
Cell Death and Differentiation, 29(10), 2089-2104. Nature Publishing Group
Cell Death and Differentiation, 2022, 29 (10), pp.2089-2104. ⟨10.1038/s41418-022-01001-3⟩
Cell Death and Differentiation, 29(10), 2089-2104. Nature Publishing Group
Glioblastoma (GBM) is the most prevalent malignant primary brain tumour in adults. GBM typically has a poor prognosis, mainly due to a lack of effective treatment options leading to tumour persistence or recurrence. We investigated the therapeutic po
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 3453, p 3453 (2021)
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
International Journal of Molecular Sciences
Volume 22
Issue 7
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
International Journal of Molecular Sciences
Volume 22
Issue 7
Altres ajuts: Universitat Autònoma de Barcelona (13th PIF Call); XarTEC SALUT (2018 XARDI 00016 / IU68-013944) The relevance of the cancer immune cycle in therapy response implies that successful treatment may trigger the exposure or the release of
Gossypol Treatment Restores Insufficient Apoptotic Function of DFF40/CAD in Human Glioblastoma Cells
Autor:
Victor J. Yuste, Daniel Ruiz-Molina, María Sánchez-Osuna, Carles Majós, Carlos Barcia, Noemi Vidal, Meritxell Roig-Martínez, Laura Martínez-Escardó, Montse Alemany, Alejandro Sánchez-Chardi, Gerard Plans, Judit Ribas, Salvio Suárez-García, María Antonia Baltrons, Jordi Bruna, Jose R. Bayascas
Publikováno v:
Repositorio Abierto de la UdL
Universitad de Lleida
Cancers
Digital.CSIC. Repositorio Institucional del CSIC
instname
Dipòsit Digital de la UB
Universidad de Barcelona
Cancers, Vol 13, Iss 5579, p 5579 (2021)
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Volume 13
Issue 21
Universitad de Lleida
Cancers
Digital.CSIC. Repositorio Institucional del CSIC
instname
Dipòsit Digital de la UB
Universidad de Barcelona
Cancers, Vol 13, Iss 5579, p 5579 (2021)
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Volume 13
Issue 21
Glioblastoma (GBM) is a highly aggressive brain tumor and almost all patients die because of relapses. GBM-derived cells undergo cell death without nuclear fragmentation upon treatment with different apoptotic agents. Nuclear dismantling determines t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a948319bb6fbcb3a10f77bae85ababb9
http://hdl.handle.net/10459.1/72611
http://hdl.handle.net/10459.1/72611
Autor:
María Sánchez-Osuna, Roser Velasco, Carlos Barcia, Jordi Bruna, Carla Granados-Colomina, Gerard Plans, Fina Martínez-Soler, Victoria Iglesias-Guimarais, Noemi Vidal, Sònia Pascual-Guiral, Laura Martínez-Escardó, Avelina Tortosa, Victor J. Yuste
Publikováno v:
Neuro-Oncology. 18:950-961
Background Glioblastoma (GBM) or grade IV astrocytoma is one of the most devastating human cancers. The loss of DFF40/CAD, the key endonuclease that triggers oligonucleosomal DNA fragmentation during apoptosis, has been linked to genomic instability
Autor:
Victoria Iglesias-Guimarais, Mercè Garcia-Belinchón, María Sánchez-Osuna, Carla Granados-Colomina, Elisenda Casanelles, Judit Ribas, Victor J. Yuste, Laura Martínez-Escardó, Sònia Pascual-Guiral
Publikováno v:
Recercat. Dipósit de la Recerca de Catalunya
instname
instname
Apoptosis is triggered by the activation of caspases and characterized by chromatin condensation and nuclear fragmentation (type II nuclear morphology). Necrosis is depicted by a gain in cell volume (oncosis), swelling of organelles, plasma membrane