Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Laura Mainz"'
Autor:
Laura Mainz, Mohamed A. F. E. Sarhan, Sabine Roth, Ursula Sauer, Katja Maurus, Elena M. Hartmann, Helen-Desiree Seibert, Andreas Rosenwald, Markus E. Diefenbacher, Mathias T. Rosenfeldt
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Macroautophagy (hereafter referred to as autophagy) is a homeostatic process that preserves cellular integrity. In mice, autophagy regulates pancreatic ductal adenocarcinoma (PDAC) development in a manner dependent on the status of the tumor suppress
Externí odkaz:
https://doaj.org/article/a7fcc1ac5ba54c5c8755dbee66ebd6bc
Autor:
Joe Nassour, Lucia Gutierrez Aguiar, Adriana Correia, Tobias T. Schmidt, Laura Mainz, Sara Przetocka, Candy Haggblom, Nimesha Tadepalle, April Williams, Maxim N. Shokhirev, Semih C. Akincilar, Vinay Tergaonkar, Gerald S. Shadel, Jan Karlseder
Publikováno v:
Nature. 614:767-773
Cancers arise through the accumulation of genetic and epigenetic alterations that enable cells to evade telomere-based proliferative barriers and achieve immortality. One such barrier is replicative crisis—an autophagy-dependent program that elimin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53d9ac87333d86767633e8a5901f1b7d
https://doi.org/10.1038/s41586-023-05710-8
https://doi.org/10.1038/s41586-023-05710-8
Autor:
Laura Mainz, Mohamed A. F. E. Sarhan, Sabine Roth, Ursula Sauer, Charis Kalogirou, Markus Eckstein, Elena Gerhard-Hartmann, Helen-Desiree Seibert, Hans-Ulrich Voelker, Carol Geppert, Andreas Rosenwald, Martin Eilers, Almut Schulze, Markus Diefenbacher, Mathias T. Rosenfeldt
The notion that macroautophagy/autophagy is a potentially attractive therapeutic target for a variety of diseases, including cancer, largely stems from pre-clinical mouse studies. Most of these examine the effects of irreversible and organ confined a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ccc1698c31744f58d51e74500c9dff6
Autor:
Laura, Mainz, Mohamed A F E, Sarhan, Sabine, Roth, Ursula, Sauer, Katja, Maurus, Elena M, Hartmann, Helen-Desiree, Seibert, Andreas, Rosenwald, Markus E, Diefenbacher, Mathias T, Rosenfeldt
Publikováno v:
Frontiers in cell and developmental biology. 10
Macroautophagy (hereafter referred to as autophagy) is a homeostatic process that preserves cellular integrity. In mice, autophagy regulates pancreatic ductal adenocarcinoma (PDAC) development in a manner dependent on the status of the tumor suppress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ae8e9f6ca10139d8af9e8c254ec669df
https://pubmed.ncbi.nlm.nih.gov/35372352
https://pubmed.ncbi.nlm.nih.gov/35372352
Autor:
Fani Ziouti, Krystyna Albrecht, Laura Mainz, Markus Sauer, Ilona Zilkowski, Stefanie Schmidt, Franziska Jundt, Stefanie Hauck, Jürgen Groll, Andres Schulze
Publikováno v:
Biomacromolecules. 20:916-926
Multiple myeloma is a common plasma-cell-derived hematologic neoplasm. While the delivery of growth-inhibiting miRNA to multiple myeloma cells would be a promising strategy to evaluate treatment options, most multiple myeloma cells are transfection-r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d080a889e802c866cbeeabb15969b16
https://doi.org/10.1021/acs.biomac.8b01553
https://doi.org/10.1021/acs.biomac.8b01553
Autor:
Mathias T. Rosenfeldt, Laura Mainz
Publikováno v:
The FEBS Journal. 285:792-808
(Macro-)autophagy is an evolutionary conserved 'self-digestion program' that serves to maintain cellular metabolism and is implicated in many pathological processes such as cancer. In recent years, an increasing number of studies in murine cancer mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::276c26ee3cca823c047ad5f8f08f6217
https://doi.org/10.1111/febs.14274
https://doi.org/10.1111/febs.14274