Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Laura M. Hodges"'
Autor:
James A. Knowles, Myrna M. Weissman, Fatemeh Haghighi, Allessandro Rotondo, Abby J. Fyer, Steven P. Hamilton, Mark W. Logue, Oleg V. Evgrafov, Laura M. Hodges
Publikováno v:
Neuropsychopharmacology. 39:2423-2431
Panic disorder (PD) is a debilitating anxiety disorder characterized by episodes of intense fear with autonomic and psychological symptoms that lead to behavioral impairment. A convergence of genetic and biological evidence implicates gamma-aminobuty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7c1e9af0e40bf96c273c8bba97657fd
https://doi.org/10.1038/npp.2014.92
https://doi.org/10.1038/npp.2014.92
Autor:
Jason M. Gow, Russ B. Altman, Deanna L. Kroetz, Svetlana Markova, Leslie W. Chinn, Laura M. Hodges, Teri E. Klein
Publikováno v:
Pharmacogenetics and Genomics. 21:152-161
ABCB1 descriptionABCB1 (MDR1) is one of many ubiquitous adenosine triphosphate (ATP)-binding cassette (ABC) genes present in all kingdoms of life that is responsible for cellular homeostasis [1–3]. ABC genes encode transporter and channel proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80a3f5a3db1135f96342e81caaf0c9a6
https://doi.org/10.1097/fpc.0b013e3283385a1c
https://doi.org/10.1097/fpc.0b013e3283385a1c
Autor:
Matthew T. Wheeler, Stephen R. Quake, Euan A. Ashley, Laura M. Hodges, Joseph V. Thakuria, Joshua W. Knowles, Kelly E. Ormond, Dmitry Pushkarev, Joan M. Hebert, Joel T. Dudley, Mark Woon, Frederick E. Dewey, Katrin Sangkuhl, Alexander A. Morgan, Alexander Wait Zaranek, Dorit S. Berlin, Abraham M. Rosenbaum, Louanne Hudgins, Michael F. Chou, Rong Chen, Atul J. Butte, George M. Church, Aleksandra Pavlovic, Teri E. Klein, Caroline F. Thorn, Henry T. Greely, Li Gong, Ryan Whaley, Russ B. Altman, Norma F. Neff, Hersh Sagreiya
Publikováno v:
The Lancet. 375:1525-1535
Summary Background The cost of genomic information has fallen steeply, but the clinical translation of genetic risk estimates remains unclear. We aimed to undertake an integrated analysis of a complete human genome in a clinical context. Methods We a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8d4f54bf2e1f647abdda37f15e523a5
https://doi.org/10.1016/s0140-6736(10)60452-7
https://doi.org/10.1016/s0140-6736(10)60452-7
Publikováno v:
Drug Metabolism and Disposition. 31:727-730
In this study, we investigated the possible involvement of acyl-CoA, reactive intermediary metabolites of 2-arylpropionic acids (profens), in protein adduct formation in rat liver homogenate and in human serum albumin (HSA) in buffer. (RS)-[1-14C]-2-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::019e30d64940392f840e92d522231cb6
https://doi.org/10.1124/dmd.31.6.727
https://doi.org/10.1124/dmd.31.6.727
Autor:
Laura M, Hodges, Svetlana M, Markova, Leslie W, Chinn, Jason M, Gow, Deanna L, Kroetz, Teri E, Klein, Russ B, Altman
Publikováno v:
Pharmacogenetics and genomics. 21(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a071e3399b09c81cc5825d961bf4a0a5
https://pubmed.ncbi.nlm.nih.gov/20216335
https://pubmed.ncbi.nlm.nih.gov/20216335
Autor:
Oscar Bravo, Ramiro Costa, Abby J. Fyer, Fatemeh Haghighi, James A. Knowles, Myrna M. Weissman, Steven P. Hamilton, Oleg V. Evgrafov, Laura M. Hodges
Publikováno v:
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. (1)
Panic disorder (PD) is a debilitating anxiety disorder, characterized by recurrent episodes of intense fear that are accompanied by autonomic and psychological symptoms leading to behavioral impairment. Basic research implicates neuropeptide-signalin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82624b0cb984ca322946f6f0123643f3
https://pubmed.ncbi.nlm.nih.gov/18452185
https://pubmed.ncbi.nlm.nih.gov/18452185
Autor:
Erynn S. Gordon, Catharine B Stack, Daniel E. Lynch, Laura M Hodges, Michael F. Christman, Neda Gharani, Tara J. Schmidlen, Margaret A. Keller
Publikováno v:
Genome Medicine
Implementation of pharmacogenomics (PGx) in clinical care can lead to improved drug efficacy and reduced adverse drug reactions. However, there has been a lag in adoption of PGx tests in clinical practice. This is due in part to a paucity of rigorous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85c359a4b7f9e57167d013cd910b22e9