Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Laura M. Frago"'
Autor:
Santiago Guerra-Cantera, Laura M. Frago, María Jiménez-Hernaiz, Roberto Collado-Pérez, Sandra Canelles, Purificación Ros, Jorge García-Piqueras, Iris Pérez-Nadador, Vicente Barrios, Jesús Argente, Julie A. Chowen
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Dietary restriction is a frequent strategy for weight loss, but adherence is difficult and returning to poor dietary habits can result in more weight gain than that previously lost. How weight loss due to unrestricted intake of a healthy die
Externí odkaz:
https://doaj.org/article/52e81c46d4ec4baaa7eed546d2745233
Autor:
Laura M. Frago, Emma Burgos-Ramos, María Rodríguez-Pérez, Sandra Canelles, Eduardo Arilla-Ferreiro, Jesús Argente, Manuela G. López, Vicente Barrios
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 5716 (2024)
Alzheimer’s disease (AD) is characterized by the deposition in the brain of senile plaques composed of amyloid-β peptides (Aβs) that increase inflammation. An endogenous peptide derived from the insulin-like growth factor (IGF)-I, glycine-proline
Externí odkaz:
https://doaj.org/article/220b19f63d97437aa64ee0b640c236c0
Autor:
Alejandra Freire-Regatillo, Sonia Diaz-Pacheco, Laura M. Frago, María-Ángeles Arévalo, Jesús Argente, Luis M. Garcia-Segura, María L. de Ceballos, Julie A. Chowen
Publikováno v:
Frontiers in Neuroanatomy, Vol 16 (2022)
The propensity to develop neurodegenerative diseases is influenced by diverse factors including genetic background, sex, lifestyle, including dietary habits and being overweight, and age. Indeed, with aging, there is an increased incidence of obesity
Externí odkaz:
https://doaj.org/article/56812f3cdf844165885607394b1cc21f
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 8, p 7065 (2023)
Leptin inhibits food intake and reduces the size of body fat depots, changing adipocyte sensitivity to insulin to restrain lipid accrual. This adipokine may modulate the production of cytokines that could diminish insulin sensitivity, particularly in
Externí odkaz:
https://doaj.org/article/4487f33869b347fc8c105f11362d9223
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 2, p 1422 (2023)
Excess body weight is frequently associated with low-grade inflammation. Evidence indicates a relationship between obesity and cancer, as well as with other diseases, such as diabetes and non-alcoholic fatty liver disease, in which inflammation and t
Externí odkaz:
https://doaj.org/article/d9612af8a1d24388835f12fdd8513dac
Autor:
Santiago Guerra-Cantera, Laura M. Frago, Roberto Collado-Pérez, Sandra Canelles, Purificación Ros, Alejandra Freire-Regatillo, María Jiménez-Hernaiz, Vicente Barrios, Jesús Argente, Julie A. Chowen
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Dietary intervention is a common tactic employed to curtail the current obesity epidemic. Changes in nutritional status alter metabolic hormones such as insulin or leptin, as well as the insulin-like growth factor (IGF) system, but little is known ab
Externí odkaz:
https://doaj.org/article/bfa841d14a2348e0ad03275120bea7b2
Autor:
Vicente Barrios, Santiago Guerra-Cantera, Álvaro Martín-Rivada, Sandra Canelles, Ana Campillo-Calatayud, Eduardo Arilla-Ferreiro, Laura M. Frago, Julie A. Chowen, Jesús Argente
Publikováno v:
Biomedicines, Vol 10, Iss 7, p 1465 (2022)
Leptin is involved in the modulation of insulin signaling in peripheral tissues, being closely associated with changes in lipid metabolism. This adipokine modifies inflammatory pathways that can interact with insulin targets in peripheral organs; how
Externí odkaz:
https://doaj.org/article/5f3806f5c94640359bef140533e32ab0
Autor:
Santiago Guerra-Cantera, Laura M. Frago, Francisca Díaz, Purificacion Ros, Maria Jiménez-Hernaiz, Alejandra Freire-Regatillo, Vicente Barrios, Jesús Argente, Julie A. Chowen
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
Insulin-like growth factor (IGF) 1 exerts a wide range of functions in mammalians participating not only in the control of growth and metabolism, but also in other actions such as neuroprotection. Nutritional status modifies the IGF system, although
Externí odkaz:
https://doaj.org/article/26322e5b026841c6bf4f2c3a65d2342d
Autor:
Vicente Barrios, Ana Campillo-Calatayud, Santiago Guerra-Cantera, Sandra Canelles, Álvaro Martín-Rivada, Laura M. Frago, Julie A. Chowen, Jesús Argente
Publikováno v:
Biomolecules, Vol 11, Iss 11, p 1734 (2021)
Leptin modulates insulin signaling and this involves the Akt pathway, which is influenced by changes in the inflammatory environment and with leptin regulating cytokine synthesis. We evaluated the association between activation of the insulin-signali
Externí odkaz:
https://doaj.org/article/37a369bc6d914d82bc80f0162464c553
Autor:
Agueda Ferrer-Donato, Ana Contreras, Laura M. Frago, Julie A. Chowen, Carmen M. Fernandez-Martos
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 19, p 10305 (2021)
Leptin has been suggested to play a role in amyotrophic lateral sclerosis (ALS), a fatal progressive neurodegenerative disease. This adipokine has previously been shown to be associated with a lower risk of ALS and to confer a survival advantage in A
Externí odkaz:
https://doaj.org/article/36b84b1527a546a0b412bfc77719a7d9