Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Laura M. Flynn"'
Autor:
Constance H. Zlot, Laura M. Flynn, Murielle M. Véniant, Edward Kim, Martin Raabe, Sally P.A. McCormick, Patricia Ambroziak, Leslie M. McEvoy, Stephen G. Young
Publikováno v:
Journal of Lipid Research, Vol 40, Iss 1, Pp 76-84 (1999)
Over the past 10 years, many laboratories have investigated lipid metabolism and atherogenesis with a variety of transgenic and gene knockout mouse models. Although many of these studies have yielded valuable insights, some have been hampered by a pa
Externí odkaz:
https://doaj.org/article/615181e0bdce417ea7895f10786451ba
Autor:
Sally P.A. McCormick, Murielle M. Véniant, Leslie M. McEvoy, Martin Raabe, Laura M. Flynn, Stephen G. Young, Edward Kim, Constance H. Zlot, Patricia Ambroziak
Publikováno v:
Journal of Lipid Research, Vol 40, Iss 1, Pp 76-84 (1999)
Over the past 10 years, many laboratories have investigated lipid metabolism and atherogenesis with a variety of transgenic and gene knockout mouse models. Although many of these studies have yielded valuable insights, some have been hampered by a pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1c46d5e9de9578ea047ab50905aff67
http://www.sciencedirect.com/science/article/pii/S0022227520333411
http://www.sciencedirect.com/science/article/pii/S0022227520333411
Autor:
Renee Stokowski, Stephen G. Young, Robert V. Farese, Dennis Huszar, Laura M. Flynn, Candace M. Cham, Maret G. Traber, Jeanne F. Loring, Vincenzo Pierotti, Sandra L. Ruland, Murielle M. Véniant
Publikováno v:
Proceedings of the National Academy of Sciences. 93:6393-6398
Apolipoprotein (apo)-B is found in two forms in mammals: apo-B100, which is made in the liver and the yolk sac, and apo-B48, a truncated protein made in the intestine. To provide models for understanding the physiologic purpose for the two forms of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5adef3a513d581db3f3229e582439ce
https://doi.org/10.1073/pnas.93.13.6393
https://doi.org/10.1073/pnas.93.13.6393
Autor:
David S. Grass, Vincenzo Pierotti, Sally P.A. McCormick, Stephen G. Young, Andrew J. Connolly, Jan Borén, Laura M. Flynn, Murielle M. Véniant, Jennifer K. Ng
Publikováno v:
Journal of Biological Chemistry. 271:11963-11970
An 87-kilobase (kb) P1 bacteriophage clone (p649) spanning the mouse apolipoprotein (apo) B gene was used to generate transgenic mice that express high levels of mouse apoB. Plasma levels of apoB, low density lipoprotein cholesterol, and low density
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22c2f1f8f0a3e63b418e144335f8b29f
https://doi.org/10.1074/jbc.271.20.11963
https://doi.org/10.1074/jbc.271.20.11963
Publikováno v:
Proceedings of the National Academy of Sciences. 92:1774-1778
Apolipoprotein B is synthesized by the intestine and the liver in mammals, where it serves as the main structural component in the formation of chylomicrons and very low density lipoproteins, respectively. Apolipoprotein B is also expressed in mammal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05a594dae076a88195236c52cf95fa3d
https://doi.org/10.1073/pnas.92.5.1774
https://doi.org/10.1073/pnas.92.5.1774
Autor:
Stephen G. Young, Bihain B, David A. Sanan, Ayrault-Jarrier M, Bernard Jacotot, Laura M. Flynn
Publikováno v:
Human Molecular Genetics. 3:741-744
Familial hypobetalipoproteinemia is caused by apolipoprotein (apo) B gene mutations and is frequently associated with a truncated apo-B protein in the plasma. Homozygosity for mutations yielding a truncated apo-B is extremely rare; fewer than five tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53bc1cf96e3285611ceba86ae08f4f3e
https://doi.org/10.1093/hmg/3.5.741
https://doi.org/10.1093/hmg/3.5.741
Autor:
Laura M. Flynn
Charismatic, beautiful Sally Flynn was the center of her daughters'imaginations, particularly Laura's. Without warning, life as they knew it changed as paranoid schizophrenia overtook Sally. Whether it was accusing Laura's father of trying to win her
Autor:
Robert L. Hamilton, Laura M. Flynn, Murielle M. Véniant, Jinny S. Wong, Constance H. Zlot, Stephen G. Young, Martin Raabe
Abetalipoproteinemia, an inherited human disease characterized by a near-complete absence of the apolipoprotein (apo) B-containing lipoproteins in the plasma, is caused by mutations in the gene for microsomal triglyceride transfer protein (MTP). We u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::461876e8dd34d72872d7e894ef7d2d85
https://europepmc.org/articles/PMC21137/
https://europepmc.org/articles/PMC21137/
Autor:
Robert V. Farese, Candace M. Cham, Jinny S. Wong, Stephen G. Young, Robert L. Hamilton, Andrew J. Connolly, Laura M. Flynn, Robert E. Pitas, Anuradha S. Pappu, Betty J. Burri
The formation of chylomicrons by the intestine is important for the absorption of dietary fats and fat-soluble vitamins (e.g., retinol, alpha-tocopherol). Apo B plays an essential structural role in the formation of chylomicrons in the intestine as w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bad6d6c2109b46a70a897bc05d647e56
https://europepmc.org/articles/PMC186005/
https://europepmc.org/articles/PMC186005/
Autor:
Stephen G. Young, Laura M. Flynn, Robert E. Hammer, Stacy Taylor, Jennifer K. Ng, Sally P.A. McCormick
Lipoprotein(a) [Lp(a)] is a lipoprotein formed by the disulfide linkage of apolipoprotein (apo) B100 of a low density lipoprotein particle to apolipoprotein(a). Prior studies have suggested that one of the C-terminal Cys residues of apo-B100 is invol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cacb08081d86d7af91d759ed9276a87c
https://europepmc.org/articles/PMC40753/
https://europepmc.org/articles/PMC40753/