Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Laura M. Fernandez"'
Autor:
Alberto Ignacio Herrando, Laura M. Fernandez, José Azevedo, Pedro Vieira, Hugo Domingos, Antonio Galzerano, Vladislav Shcheslavskiy, Richard J. Heald, Amjad Parvaiz, Pedro Garcia da Silva, Mireia Castillo-Martin, João L. Lagarto
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Colorectal cancer (CRC) ranks among the most prevalent malignancies worldwide, driving a quest for comprehensive characterization methods. We report a characterization of the ex vivo autofluorescence lifetime fingerprint of colorectal tissue
Externí odkaz:
https://doaj.org/article/7307cd3266154df18fc6c3a2ab773d15
Zebrafish Avatar-test forecasts clinical response to chemotherapy in patients with colorectal cancer
Autor:
Bruna Costa, Marta F. Estrada, António Gomes, Laura M. Fernandez, José M. Azevedo, Vanda Póvoa, Márcia Fontes, António Alves, António Galzerano, Mireia Castillo-Martin, Ignacio Herrando, Shermann Brandão, Carla Carneiro, Vítor Nunes, Carlos Carvalho, Amjad Parvaiz, Ana Marreiros, Rita Fior
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Cancer patients often undergo rounds of trial-and-error to find the most effective treatment because there is no test in the clinical practice for predicting therapy response. Here, we conduct a clinical study to validate the zebrafish patie
Externí odkaz:
https://doaj.org/article/f2a697a27da54e909f3270301d64d5d8
Autor:
Bruna Costa, Laura M. Fernandez, Oriol Parés, Ricardo Rio-Tinto, Inês Santiago, Mireia Castillo-Martin, Amjad Parvaiz, Rita Fior
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Neoadjuvant chemoradiation (nCRT) followed by surgery represents the standard of care in patients with locally advanced rectal cancer. Increasing radiotherapy (RT) doses and chemotherapy cycles with 5FU have been associated with increased rates of co
Externí odkaz:
https://doaj.org/article/bcaa07441a854ab6afa9e33c90eee57f
Autor:
Steven D. Wexner, Laura M. Fernandez, Dimitri Krizzuk, Ido Mizrahi, Argyrios Ioannidis, Mahmoud Abu-Gazala
Publikováno v:
Colorectal Disease. 23:2948-2954
AIM The aim of this work was to compare the results of elective minimally invasive surgery between patients with complicated sigmoid diverticulitis and those with uncomplicated disease. METHOD An institutional review board-approved database was searc
Autor:
Laura M. Fernandez, Inês Santiago, Bernardete Rodrigues, Nuno Figueiredo, Oriol Pares, Maria Joao Barata, Celso Matos, Antonio Galzerano
Publikováno v:
Insights into Imaging, Vol 12, Iss 1, Pp 1-17 (2021)
Insights into Imaging
Insights into Imaging
In the past nearly 20 years, organ-sparing when no apparent viable tumour is present after neoadjuvant therapy has taken an increasingly relevant role in the therapeutic management of locally-advanced rectal cancer patients. The decision to include a
Autor:
Angelita Habr-Gama, S. Ravi, R. Kushwaha, Zaman Z. Mamedli, Koen C.M.J. Peeters, Anna Martling, Elma Meershoek-Klein Kranenbarg, Geerard L. Beets, Arthur Sun Myint, S. Loganathan, Gustavo Rossi, Wolfgang Gaertner, S. Duff, J. Heat, D. Vimalchandran, Malcolm S Wilson, J. Hobbiss, K.H. Siddiqui, Krzysztof Bujko, Fernando Sanchez Loria, Maxime J M van der Valk, Rodrigo Oliva Perez, Marit E van der Sande, Renu R. Bahadoer, P. Mitchell, A. Blower, Jarno Melenhorst, Claudio Coco, J. Salaman, Guilherme Pagin São Julião, Denise E. Hilling, Oktar Asoglu, M.H. Solkar, S.H. Pettit, S.T. Dwyer, P. Vieira, Anders Jakobsen, N. Lees, Rita Barroca, Christopher M. Cunningham, Simon Gollins, S. Ward, Jean-Pierre Gerard, J. Epstein, James Hill, Albert Wolthuis, Nuno Figueiredo, A. Bhowmick, Nagarajan Pranesh, Nigel Scott, M. Braun, J. Harrison, Jing Zhang, Oriol Pares, André D’Hoore, R. Rajaganeshan, K. Riyad, R. Harris, Inês Santiago, Soledad Iseas, Paul E Fulford, Alejandro Pairola, Charlotte Verberne, B. Taylor, Des C. Winter, M. Paraoan, Annet G H Roodvoets, P. Carter, Harm J. T. Rutten, Fernando López Campos, Zhen Zhang, A. Abdelrazeq, Carlos A. Vaccaro, M. Saeed, C. Smart, Laura M. Fernandez, Carlijn Witjes, T.Y. Linn, K. Telford, Chelliah Selvasekar, D. Richards, Peirong Ding, J. Beveridge, D. Evans, Andrew G Renehan, Carlos Alfredo Lopes de Carvalho, Cornelis J.H. van de Velde, David R. Jones, Robert Madoff, Z. Huq, Sthela M. Murad-Regadas, Bruna Borba Vailati, Sarah T O'Dwyer, Klaus E. Matzel, Eduardo Huertas, L. Jones, U. Khan, S. Rawat, Gabriel Dimofte
Publikováno v:
Lancet oncology, 22(1), 43-50. Elsevier Science
The Lancet Oncology, 22(1), 43-50. ELSEVIER SCIENCE INC
Lancet Oncology, 22(1), 43-50. Lancet Publishing Group
The Lancet Oncology, 22(1), 43-50. ELSEVIER SCIENCE INC
Lancet Oncology, 22(1), 43-50. Lancet Publishing Group
Summary Background Watch and wait is a novel management strategy in patients with rectal cancer who have a clinical complete response after neoadjuvant chemoradiotherapy. Surveillance of these patients is generally intensive, because local regrowth (
Autor:
Laura M Fernandez, Angelita Habr-Gama, Mireia Castillo-Martin, P. Vieira, Carlos Carvalho, Nuno Figueiredo, Inês Santiago, Guilherme Pagin São Julião, Rodrigo Oliva Perez, Irfan Ul Islam Nasir, Amjad Parvaiz, Oriol Pares, Bruna Borba Vailati
Publikováno v:
Diseases of the Colon & Rectum. 63:1053-1062
Background Patients with rectal cancer who achieve complete clinical response after neoadjuvant chemoradiation have been managed nonoperatively. Thirty percent of these patients may develop a local regrowth, and salvage resection with radical surgery
Autor:
Guilherme Pagin São Julião, Rodrigo Oliva Perez, Andres Andrade, Angelita Habr-Gama, Joaquim Gama-Rodrigues, Laura M. Fernandez, Sergio Eduardo Alonso Araujo, Bruna Borba Vailati
Publikováno v:
Diseases of the Colon & Rectum. 62:802-808
Patients with rectal cancer who achieve complete clinical response after neoadjuvant chemoradiation have been managed by organ-preserving strategies and acceptable long-term outcomes. Controversy still exists regarding optimal timing for the assessme
Autor:
Bruna Borba Vailati, Angelita Habr-Gama, Nuno Figueiredo, Rodrigo Oliva Perez, Joaquim Gama-Rodrigues, Guilherme Pagin São Julião, Laura M. Fernandez, Cinthia D. Ortega
Publikováno v:
Diseases of the Colon & Rectum. 62:675-683
Background Select patients with complete clinical response to chemoradiation have been managed without radical surgery. The presence of radiologic evidence of nodal metastases at baseline could be a risk factor for local tumor regrowth, more advanced
Autor:
Georgios Karagkounis, Mit Dattani, Bruna Borba Vailati, Rodrigo Oliva Perez, Guilherme Pagin São Julião, Matthew F. Kalady, Laura M. Fernandez, Angelita Habr-Gama
Publikováno v:
Annals of Surgery. 272:138-144
Analyze conditional recurrence-free survival (cRFS) for rectal cancer patients with complete clinical response (cCR) after neoadjuvant chemoradiation (nCRT) managed nonoperatively after each year without recurrence.Select patients with cCR after nCRT