Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Laura M. Cole"'
Autor:
Sophie M. Pearce, Neil A. Cross, David P. Smith, Malcolm R. Clench, Lucy E. Flint, Gregory Hamm, Richard Goodwin, James I. Langridge, Emmanuelle Claude, Laura M. Cole
Publikováno v:
Metabolites, Vol 14, Iss 6, p 315 (2024)
A multimodal mass spectrometry imaging (MSI) approach was used to investigate the chemotherapy drug-induced response of a Multicellular Tumour Spheroid (MCTS) 3D cell culture model of osteosarcoma (OS). The work addresses the critical demand for enha
Externí odkaz:
https://doaj.org/article/33234cee908948bdb3d0d0201de8eb8b
Autor:
Joshua Millar, Luke Gibbons, Catia Costa, Ella Schneider, Johanna von Gerichten, Melanie J. Bailey, Susan Campbell, Catherine Duckett, Sarah Doyle, Laura M. Cole
Publikováno v:
Analytica, Vol 4, Iss 3, Pp 264-279 (2023)
The metallome has been involved in the pathological investigation into ocular tissue for decades; however, as technologies advance, more information can be ascertained from individual tissue sections that were not previously possible. Herein, a demon
Externí odkaz:
https://doaj.org/article/cd9d9cdaae364613b307ba81de363f2a
Autor:
Sonia Guarnerio, Robert Tempest, Rawan Maani, Stuart Hunt, Laura M. Cole, Christine L. Le Maitre, Keith Chapple, Nicholas Peake
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 23, p 16755 (2023)
The development of novel screening tests aims to support early asymptomatic diagnosis and subtyping patients according to similar traits in the heterogeneous cancer cohort. Extracellular vesicles (EVs) are promising candidates for the detection of di
Externí odkaz:
https://doaj.org/article/364cd0f1aed0428b9bd1938f792da6e8
Publikováno v:
Metabolites, Vol 12, Iss 12, p 1239 (2022)
Determining the locations of proteins within the eye thought to be involved in ocular pathogenesis is important to determine how best to target them for therapeutic benefits. However, immunohistochemistry is limited by the availability and specificit
Externí odkaz:
https://doaj.org/article/988dffe7684147f2939991da1e381af7
Autor:
Laura M. Cole, Joshua Handley, Emmanuelle Claude, Catherine J. Duckett, Hardeep S. Mudhar, Karen Sisley, Malcolm R. Clench
Publikováno v:
Metabolites, Vol 11, Iss 8, p 560 (2021)
Matrix assisted laser desorption ionisation mass spectrometry imaging (MALDI-MSI), was used to obtain images of lipids and metabolite distribution in formalin fixed and embedded in paraffin (FFPE) whole eye sections containing primary uveal melanomas
Externí odkaz:
https://doaj.org/article/c2c20a9c9a4f4e419a1da98f2f7b985b
Autor:
Lucy E. Flint, Gregory Hamm, Joseph D. Ready, Stephanie Ling, Catherine J. Duckett, Neil A. Cross, Laura M. Cole, David P. Smith, Richard J. A. Goodwin, Malcolm R. Clench
Publikováno v:
Metabolites, Vol 11, Iss 8, p 506 (2021)
Osteosarcoma (OS) is the most common primary bone malignancy and largely effects adolescents and young adults, with 60% of patients under the age of 25. There are multiple cell models of OS described in vitro that express the specific genetic alterat
Externí odkaz:
https://doaj.org/article/f2726bcdd41a49d6a1aeac6eff90899a
Publikováno v:
Metabolites, Vol 10, Iss 9, p 366 (2020)
Multiple sclerosis (MS) is a neurodegenerative inflammatory disease where an autoimmune response to components of the central nervous system leads to a loss of myelin and subsequent neurological deterioration. People with MS can develop primary or se
Externí odkaz:
https://doaj.org/article/ddf15ae2847e4b2dbde7cc9065860340
Publikováno v:
Science & Justice. 62:602-609
For the past 7 years, Matrix Assisted Laser Desorption Ionisation Mass Spectrometry (MALDI MS) based methods have been developed and published for the forensic detection of blood in stains and fingermarks. However, in the view of adoption in an opera
Autor:
David Smith, Gregory Hamm, Richard J. A. Goodwin, Malcolm R. Clench, Catherine J. Duckett, Joseph D. Ready, Stephanie Ling, Lucy E Flint, Neil Cross, Laura M. Cole
Publikováno v:
Metabolites, Vol 11, Iss 506, p 506 (2021)
Metabolites
Volume 11
Issue 8
Metabolites
Volume 11
Issue 8
Osteosarcoma (OS) is the most common primary bone malignancy and largely effects adolescents and young adults, with 60% of patients under the age of 25. There are multiple cell models of OS described in vitro that express the specific genetic alterat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbc7579796a29305f8c82dcff6300d8e
https://shura.shu.ac.uk/28898/1/metabolites-11-00506.pdf
https://shura.shu.ac.uk/28898/1/metabolites-11-00506.pdf
Autor:
Joshua Handley, Karen Sisley, Malcolm R. Clench, Catherine J. Duckett, Emmanuelle Claude, Hardeep Singh Mudhar, Laura M. Cole
Publikováno v:
Metabolites
Metabolites, Vol 11, Iss 560, p 560 (2021)
Metabolites, Vol 11, Iss 560, p 560 (2021)
Matrix assisted laser desorption ionisation mass spectrometry imaging (MALDI-MSI), was used to obtain images of lipids and metabolite distribution in formalin fixed and embedded in paraffin (FFPE) whole eye sections containing primary uveal melanomas