Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Laura M Parkes"'
Autor:
Stavros Stivaros, Shruti Garg, Maria Tziraki, Ying Cai, Owen Thomas, Joseph Mellor, Andrew A. Morris, Carly Jim, Karolina Szumanska-Ryt, Laura M Parkes, Hamied A. Haroon, Daniela Montaldi, Nicholas Webb, John Keane, Francisco X. Castellanos, Alcino J. Silva, Sue Huson, Stephen Williams, D. Gareth Evans, Richard Emsley, Jonathan Green, SANTA Consortium
Publikováno v:
Molecular Autism, Vol 9, Iss 1, Pp 1-13 (2018)
Abstract Background Neurofibromatosis 1 (NF1) is a monogenic model for syndromic autism. Statins rescue the social and cognitive phenotype in animal knockout models, but translational trials with subjects > 8 years using cognition/behaviour outcomes
Externí odkaz:
https://doaj.org/article/dafd5e775ca6491c9657b16a73c4e0fa
Autor:
Sylviane Defres, Simon S Keller, Kumar Das, Rishma Vidyasagar, Laura M Parkes, Girvan Burnside, Michael Griffiths, Michael Kopelman, Neil Roberts, Tom Solomon, ENCEPH UK study group
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0170215 (2017)
To assess whether it is feasible to quantify acute change in temporal lobe volume and total oedema volumes in herpes simplex virus (HSV) encephalitis as a preliminary to a trial of corticosteroid therapy.The study analysed serially acquired magnetic
Externí odkaz:
https://doaj.org/article/a7b9dfb6d6e0463db6a4b486cebea14f
Autor:
Conor Owens-Walton, Talia M. Nir, Sarah Al-Bachari, Sonia Ambrogi, Tim J. Anderson, Ítalo Karmann Aventurato, Fernando Cendes, Yao-Liang Chen, Valentina Ciullo, Phil Cook, John C. Dalrymple-Alford, Michiel F. Dirkx, Jason Druzgal, Hedley C. A. Emsley, Rachel Guimarães, Hamied A. Haroon, Rick C. Helmich, Michele T. Hu, Martin E. Johansson, Ho Bin Kim, Johannes C. Klein, Max Laansma, Katherine E. Lawrence, Christine Lochner, Clare Mackay, Corey T. McMillan, Tracy R. Melzer, Leila Nabulsi, Ben Newman, Peter Opriessnig, Laura M. Parkes, Clelia Pellicano, Fabrizio Piras, Federica Piras, Lukas Pirpamer, Toni L. Pitcher, Kathleen L. Poston, Annerine Roos, Lucas Scárdua Silva, Reinhold Schmidt, Petra Schwingenschuh, Marian Shahid-Besanti, Gianfranco Spalletta, Dan J. Stein, Sophia I. Thomopoulos, Duygu Tosun, Chih-Chien Tsai, Odile A. van den Heuvel, Eva van Heese, Daniela Vecchio, Julio E. Villalón-Reina, Chris Vriend, Jiun-Jie Wang, Yih-Ru Wu, Clarissa Lin Yasuda, Paul M. Thompson, Neda Jahanshad, Ysbrand van der Werf
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-12 (2024)
Abstract The progression of Parkinson’s disease (PD) is associated with microstructural alterations in neural pathways, contributing to both motor and cognitive decline. However, conflicting findings have emerged due to the use of heterogeneous met
Externí odkaz:
https://doaj.org/article/abdb13d4596d46599f5bc49288648bf9
Publikováno v:
PLoS Biology, Vol 14, Iss 5, p e1002451 (2016)
Sleep plays a role in memory consolidation. This is demonstrated by improved performance and neural plasticity underlying that improvement after sleep. Targeted memory reactivation (TMR) allows the manipulation of sleep-dependent consolidation throug
Externí odkaz:
https://doaj.org/article/5128d37452414cf4ba4d6dd2c9c16d61
Autor:
Caroline A Lea-Carnall, Marcelo A Montemurro, Nelson J Trujillo-Barreto, Laura M Parkes, Wael El-Deredy
Publikováno v:
PLoS Computational Biology, Vol 12, Iss 2, p e1004740 (2016)
Neural oscillations occur within a wide frequency range with different brain regions exhibiting resonance-like characteristics at specific points in the spectrum. At the microscopic scale, single neurons possess intrinsic oscillatory properties, such
Externí odkaz:
https://doaj.org/article/d86bde09d5d94aa3b9ee8371cf5c92a9
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e78844 (2013)
BACKGROUND: Pervasive negative thoughts about the self are central to the experience of depression. Brain imaging studies in the general population have localised self-related cognitive processing to areas of the medial pre-frontal cortex. AIMS: To u
Externí odkaz:
https://doaj.org/article/acc9538f66ad4a1eacb67bc428611616
Autor:
Yolanda Ohene, William J. Harris, Elizabeth Powell, Nina W. Wycech, Katherine F. Smethers, Samo Lasič, Kieron South, Graham Coutts, Andrew Sharp, Catherine B. Lawrence, Hervé Boutin, Geoff J. M. Parker, Laura M. Parkes, Ben R. Dickie
Publikováno v:
Fluids and Barriers of the CNS, Vol 20, Iss 1, Pp 1-18 (2023)
Abstract Blood–brain barrier (BBB) dysfunction occurs in many brain diseases, and there is increasing evidence to suggest that it is an early process in dementia which may be exacerbated by peripheral infection. Filter-exchange imaging (FEXI) is an
Externí odkaz:
https://doaj.org/article/993f91b80b9647f1af20428f0e2b0cb2
Autor:
Elizabeth Powell, Yolanda Ohene, Marco Battiston, Ben R. Dickie, Laura M. Parkes, Geoff J. M. Parker
Publikováno v:
Powell, E, Ohene, Y, Battiston, M, Dickie, B R, Parkes, L M & Parker, G J M 2023, ' Blood-brain barrier water exchange measurements using FEXI : Impact of modeling paradigm and relaxation time effects ', Magnetic Resonance in Medicine, vol. 90, no. 1, pp. 34-50 . https://doi.org/10.1002/mrm.29616
Purpose: To evaluate potential modeling paradigms and the impact of relaxation time effects on human blood-brain barrier (BBB) water exchange measurements using FEXI (BBB-FEXI), and to quantify the accuracy, precision, and repeatability of BBB-FEXI e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec3006568994026de6a544ef07929795
http://www.scopus.com/inward/record.url?scp=85150489515&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85150489515&partnerID=8YFLogxK
Autor:
Ben R Dickie, Tao Jin, Ping Wang, Rainer Hinz, William Harris, Hervé Boutin, Geoff JM Parker, Laura M Parkes, Julian C Matthews
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 42:2066-2079
Chemical-exchange spin-lock (CESL) MRI can map regional uptake and utilisation of glucose in the brain at high spatial resolution (i.e sub 0.2 mm3 voxels). We propose two quantitative kinetic models to describe glucose-induced changes in tissue R1ρ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b565fe5ebeab58fd00e545ffeeb33650
https://doi.org/10.1177/0271678x221108841
https://doi.org/10.1177/0271678x221108841
A technique for quantifying regional blood-brain barrier (BBB) water exchange rates using contrast-enhanced arterial spin labelling (CE-ASL) is presented and evaluated in simulations and in vivo. The two-compartment ASL model describes the water exch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a50b5292e0f5538538c0b2896a1ef3f4
https://doi.org/10.1101/2023.02.16.528529
https://doi.org/10.1101/2023.02.16.528529