Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Laura M, Cox"'
Autor:
Qingqi Lin, Yair Dorsett, Ali Mirza, Helen Tremlett, Laura Piccio, Erin E. Longbrake, Siobhan Ni Choileain, David A. Hafler, Laura M. Cox, Howard L. Weiner, Takashi Yamamura, Kun Chen, Yufeng Wu, Yanjiao Zhou
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-13 (2024)
Abstract Background Previous studies have identified a diverse group of microbial taxa that differ between patients with multiple sclerosis (MS) and the healthy population. However, interpreting findings on MS-associated microbiota is challenging, as
Externí odkaz:
https://doaj.org/article/fdb2ecafbcc14cf782be9fc55e5cfd28
Autor:
Caroline Wasén, Leah C. Beauchamp, Julia Vincentini, Shuqi Li, Danielle S. LeServe, Christian Gauthier, Juliana R. Lopes, Thais G. Moreira, Millicent N. Ekwudo, Zhuoran Yin, Patrick da Silva, Rajesh K. Krishnan, Oleg Butovsky, Laura M. Cox, Howard L. Weiner
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract The gut microbiota and microglia play critical roles in Alzheimer’s disease (AD), and elevated Bacteroides is correlated with cerebrospinal fluid amyloid-β (Aβ) and tau levels in AD. We hypothesize that Bacteroides contributes to AD by m
Externí odkaz:
https://doaj.org/article/5a13ffd6448641528a8fa807f7ea2f20
Autor:
Laura Wieg, Jason C. Ciola, Caroline C. Wasén, Fidelia Gaba, Brianna R. Colletti, Maren K. Schroeder, Robert G. Hinshaw, Millicent N. Ekwudo, David M. Holtzman, Takashi Saito, Hiroki Sasaguri, Takaomi C. Saido, Laura M. Cox, Cynthia A. Lemere
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 17, p 9379 (2024)
Cosmic radiation experienced during space travel may increase the risk of cognitive impairment. While simulated galactic cosmic radiation (GCRsim) has led to memory deficits in wildtype (WT) mice, it has not been investigated whether GCRsim in combin
Externí odkaz:
https://doaj.org/article/1d54f1557c004e96900c2809e2acba91
Autor:
Hadi Abou-El-Hassan, Rafael M. Rezende, Saef Izzy, Galina Gabriely, Taha Yahya, Bruna K. Tatematsu, Karl J. Habashy, Juliana R. Lopes, Gislane L. V. de Oliveira, Amir-Hadi Maghzi, Zhuoran Yin, Laura M. Cox, Rajesh Krishnan, Oleg Butovsky, Howard L. Weiner
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Traumatic brain injury (TBI) is a leading cause of morbidity and mortality. The innate and adaptive immune responses play an important role in the pathogenesis of TBI. Gamma-delta (γδ) T cells have been shown to affect brain immunopatholog
Externí odkaz:
https://doaj.org/article/6a5a1b424fcc41eabd0e3bb1b781dd2c
Autor:
Rafael M. Rezende, Laura M. Cox, Thais G. Moreira, Shirong Liu, Selma Boulenouar, Fyonn Dhang, Danielle S. LeServe, Brenda N. Nakagaki, Juliana R. Lopes, Bruna K. Tatematsu, Luisa Lemos, Julia Mayrink, Eduardo L. C. Lobo, Lydia Guo, Marilia G. Oliveira, Chantal Kuhn, Howard L. Weiner
Publikováno v:
Microbiome, Vol 11, Iss 1, Pp 1-21 (2023)
Abstract Background Gamma-delta (γδ) T cells are a major cell population in the intestinal mucosa and are key mediators of mucosal tolerance and microbiota composition. Little is known about the mechanisms by which intestinal γδ T cells interact
Externí odkaz:
https://doaj.org/article/ebed5f4b59324144aeb29e2ce77e641f
Autor:
Paola Bianchimano, Graham J. Britton, David S. Wallach, Emma M. Smith, Laura M. Cox, Shirong Liu, Kacper Iwanowski, Howard L. Weiner, Jeremiah J. Faith, Jose C. Clemente, Stephanie K. Tankou
Publikováno v:
Microbiome, Vol 10, Iss 1, Pp 1-22 (2022)
Abstract Background The gut microbiome plays an important role in autoimmunity including multiple sclerosis and its mouse model called experimental autoimmune encephalomyelitis (EAE). Prior studies have demonstrated that the multiple sclerosis gut mi
Externí odkaz:
https://doaj.org/article/789a055f20764362b6a206a407712ee1
Autor:
Laura M. Cox, Narghes Calcagno, Christian Gauthier, Charlotte Madore, Oleg Butovsky, Howard L. Weiner
Publikováno v:
Microbiome, Vol 10, Iss 1, Pp 1-13 (2022)
Abstract Background The gut microbiota can affect neurologic disease by shaping microglia, the primary immune cell in the central nervous system (CNS). While antibiotics improve models of Alzheimer’s disease, Parkinson’s disease, multiple scleros
Externí odkaz:
https://doaj.org/article/9b9770b25e4d498dbd0d2e808ab1f5bc
Autor:
Thais G. Moreira, Davide Mangani, Laura M. Cox, Jeffrey Leibowitz, Eduardo. L. C. Lobo, Mariana A. Oliveira, Christian D. Gauthier, Brenda N. Nakagaki, Valerie Willocq, Anya Song, Lydia Guo, David C. A. Lima, Gopal Murugaiyan, Oleg Butovsky, Galina Gabriely, Ana C. Anderson, Rafael M. Rezende, Ana Maria C. Faria, Howard L. Weiner
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Dendritic cells initiate and regulate adaptive immunity and differ according to gut anatomical location. Here the authors show that DC residing in the upper and lower intestines show differential PD-L1 and XCR1 expression and drive specific T cell re
Externí odkaz:
https://doaj.org/article/f3a9efe8e82843f4aa28ca11b29546aa
Autor:
Panayota Kolypetri, Shirong Liu, Laura M. Cox, Mai Fujiwara, Radhika Raheja, Dvora Ghitza, Anya Song, Dominique Daatselaar, Valerie Willocq, Howard L. Weiner
Publikováno v:
iScience, Vol 24, Iss 4, Pp 102356- (2021)
Summary: Splenic Ly6Chigh monocytes are innate immune cells involved in the regulation of central nervous system-related diseases. Recent studies have reported the shaping of peripheral immune responses by the gut microbiome via mostly unexplored pat
Externí odkaz:
https://doaj.org/article/bd95a85eaa3743389ae962d12f675f6a
Autor:
Soo Ching Lee, Mei San Tang, Yvonne A L Lim, Seow Huey Choy, Zachary D Kurtz, Laura M Cox, Uma Mahesh Gundra, Ilseung Cho, Richard Bonneau, Martin J Blaser, Kek Heng Chua, P'ng Loke
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 4, p e0009325 (2021)
[This corrects the article DOI: 10.1371/journal.pntd.0002880.].
Externí odkaz:
https://doaj.org/article/c20feda6af6547bea3c2157f96ab1c4d