Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Laura López-Vicente"'
Autor:
Santiago Ramon y Cajal, Inés de Torres, Javier Hernández-Losa, Matilde Lleonart, Elisabet Argelaguet, Laura Coch, Berta Pons, Gemma Armengol, Laura López-Vicente
Supplementary Data from Regulation of Replicative and Stress-Induced Senescence by RSK4, which is Down-regulated in Human Tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8726971fef44bdce535efa03e6ac9a03
https://doi.org/10.1158/1078-0432.22439952
https://doi.org/10.1158/1078-0432.22439952
Autor:
Santiago Ramon y Cajal, Inés de Torres, Javier Hernández-Losa, Matilde Lleonart, Elisabet Argelaguet, Laura Coch, Berta Pons, Gemma Armengol, Laura López-Vicente
Purpose: The control of senescence and its biochemical pathways is a crucial factor for understanding cell transformation. In a large RNA interference screen, the RSK4 gene was found to be related to p53-dependent arrest. The purpose of the present s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b2ecd49b49f2a9bf1b97191d0ba71d3
https://doi.org/10.1158/1078-0432.c.6517335.v1
https://doi.org/10.1158/1078-0432.c.6517335.v1
Autor:
Laura López-Vicente, A Mazo, Sara Simonetti, Josep Castellví, S. Ramón y Cajal, Matilde E. Lleonart, Cleofé Romagosa
Publikováno v:
Oncogene. 30:2087-2097
p16(Ink4a) is a protein involved in regulation of the cell cycle. Currently, p16(Ink4a) is considered a tumor suppressor protein because of its physiological role and downregulated expression in a large number of tumors. Intriguingly, overexpression
Autor:
María Ángeles Vázquez-Sánchez, Elisabet Argelaguet, Laura Coch, Berta Pons, Laura López-Vicente, A. Martínez, Gemma Armengol, Vicente Peg, Santiago Ramón y Cajal, Javier Hernández-Losa
Publikováno v:
International Journal of Oncology.
Cell signaling pathways and protein translation are crucial for understanding malignant transformation. 4E-BP1 and the eIF4F complex regulate cap-dependent translation. We investigated how 4E-BP1 and eIF4E phosphorylation status affects in vitro and
Autor:
Laura Coch, Santiago Ramón y Cajal, Laura López-Vicente, Cristina Teixidó, Gemma Armengol, Berta Pons, Javier Hernández-Losa
Publikováno v:
Carcinogenesis. 32(4)
p90 Ribosomal S6 kinase (RSK) 4 is a serine―threonine kinase that belongs to the p90RSK family. RSK4 has been proposed as a tumor suppressor gene, related with anti-invasive activity, inhibition of the RAS―mitogen-activated protein kinase (MAPK)
Autor:
Francisco Vidal, Laura López-Vicente, C. Blanco, Hiroshi Kondoh, Dominique Gallardo, Amancio Carnero, Miriam Cuatrecasas, Federico Rojo, S. Ramón y Cajal, Matilde E. Lleonart, M. Diaz-Fuertes
Publikováno v:
ResearcherID
Scopus-Elsevier
Scopus-Elsevier
Human epithelial tumors need to accumulate multiple genetic alterations to form invasive carcinomas. These genetic alterations are related with growth factor receptors, cell signalling, the cell cycle and cell invasiveness. Importantly, cells need to