Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Laura Llacuna"'
Autor:
Laura Llacuna, Núria Mach
Publikováno v:
Revista Española de Nutrición Humana y Dietética, Vol 16, Iss 1 (2011)
La naturaleza de la asociación entre radicales libres y cáncer es compleja y paradójica. Parece que los radicales libres y el estrés oxidativo pueden inducir cáncer, pero al mismo tiempo las células transformadas, es decir, las células cancero
Externí odkaz:
https://doaj.org/article/ccb0c3c949f14dfd8a6f455a443e84dd
Autor:
Sandra Angulo, Albert Morales, Silvio Danese, Laura Llacuna, Maria Carme Masamunt, Nicole Pultz, Maria Grazia Cifone, Claudio De Simone, Salvadora Delgado, Jordi Vila, Julián Panés, Curtis Donskey, Jose C Fernández-Checa, Claudio Fiocchi, Miquel Sans
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e16953 (2011)
Probiotics appear to be beneficial in inflammatory bowel disease, but their mechanism of action is incompletely understood. We investigated whether probiotic-derived sphingomyelinase mediates this beneficial effect.Neutral sphingomyelinase (NSMase) a
Externí odkaz:
https://doaj.org/article/a1abda470a0548a297ecdab23e266c48
Autor:
Josep M Lluis, Laura Llacuna, Claudia von Montfort, Cristina Bárcena, Carlos Enrich, Albert Morales, José C Fernandez-Checa
Publikováno v:
PLoS ONE, Vol 4, Iss 11, p e8059 (2009)
BACKGROUND:Hypoxia-mediated HIF-1alpha stabilization and NF-kappaB activation play a key role in carcinogenesis by fostering cancer cell survival, angiogenesis and tumor invasion. Gangliosides are integral components of biological membranes with an i
Externí odkaz:
https://doaj.org/article/cd2aaf22f0d04fddbba0479db3b072a2
Autor:
José C. Fernández-Checa, Anna Colell, Carmen García-Ruiz, Jesús Prieto, Bruno Antonsson, Gorka Basañez, Oihana Terrones, Josep M. Lluis, Laura Llacuna, Albert Morales, Joan Montero
Supplementary Methods, Figures 1-8 from Mitochondrial Cholesterol Contributes to Chemotherapy Resistance in Hepatocellular Carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08a6bf6d9062108aefaa6722a36fc534
https://doi.org/10.1158/0008-5472.22374950
https://doi.org/10.1158/0008-5472.22374950
Autor:
José C. Fernández-Checa, Anna Colell, Carmen García-Ruiz, Jesús Prieto, Bruno Antonsson, Gorka Basañez, Oihana Terrones, Josep M. Lluis, Laura Llacuna, Albert Morales, Joan Montero
Cholesterol metabolism is deregulated in carcinogenesis, and cancer cells exhibit enhanced mitochondrial cholesterol content whose role in cell death susceptibility and cancer therapy has not been investigated. Here, we describe that mitochondria fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9141dbf4cd7526bab6e099675ebf8b13
https://doi.org/10.1158/0008-5472.c.6497654
https://doi.org/10.1158/0008-5472.c.6497654
Autor:
Laura Llacuna, Stefania Asciutti, Tobias Karlberg, Roberto Pellicciari, Andrea Carotti, Daniele Bellocchi, Emidio Camaioni, Herwig Schüler, Paride Liscio, Stuart A. Aaronson, Antonio Macchiarulo
Publikováno v:
Journal of Medicinal Chemistry. 57:2807-2812
Searching for selective tankyrases (TNKSs) inhibitors, a new small series of 6,8-disubstituted triazolo[4,3-b]piridazines has been synthesized and characterized biologically. Structure-based optimization of the starting hit compound NNL (3) prompted
Autor:
Lukas Peintner, Gerhard Krumschnabel, Florian J. Bock, Gottfried Baier, Maria C. Tanzer, Claudia Manzl, Andreas Villunger, Natascha Hermann-Kleiter, Laura Llacuna, José Yélamos
Publikováno v:
Cell Death and Differentiation
Cell Death and Differentiation; Vol 20
Cell Death and Differentiation; Vol 20
Activation of NF-κB (nuclear factor of kappa light chain gene enhancer in B cells) in response to DNA damage is considered to contribute to repair of genetic lesions, increased cell survival and cytokine release. The molecular mechanisms orchestrati
Publikováno v:
Hepatology. 44:561-572
The molecular mechanisms of hepatic ischemia/reperfusion (I/R) damage are incompletely understood. We investigated the role of ceramide in a murine model of warm hepatic I/R injury. This sphingolipid induces cell death and participates in tumor necro
Autor:
Juan Martín-Caballero, Laura Llacuna, Jordi Farrés, Valérie Schreiber, Carlos Martinez, Juan José Lozano, Cristina Ruiz-Herguido, Françoise Dantzer, Anna Bigas, Andreas Villunger, Coral Ampurdanés, José Yélamos
Publikováno v:
Blood
Blood, American Society of Hematology, 2013, 122 (1), pp.44-54. ⟨10.1182/blood-2012-12-472845⟩
Blood, American Society of Hematology, 2013, 122 (1), pp.44-54. ⟨10.1182/blood-2012-12-472845⟩
Hematopoietic stem cells self-renew for life to guarantee the continuous supply of all blood cell lineages. Here we show that Poly(ADP-ribose) polymerase-2 (Parp-2) plays an essential role in hematopoietic stem/progenitor cells (HSPC) survival under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5e19e1d6dfe1e045ce88b48a58fd576
https://hal.archives-ouvertes.fr/hal-02369957
https://hal.archives-ouvertes.fr/hal-02369957
Autor:
Miquel Sans, Maria Carme Masamunt, Albert Morales, Sandra Angulo, Laura Llacuna, Julián Panés, José C. Fernández-Checa, Maria Grazia Cifone, Jordi Vila, Nicole J. Pultz, Claudio Fiocchi, Curtis J. Donskey, Silvio Danese, Salvadora Delgado, Claudio De Simone
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Dipòsit Digital de la UB
Universidad de Barcelona
PLoS ONE
Recercat. Dipósit de la Recerca de Catalunya
PLoS ONE, Vol 6, Iss 3, p e16953 (2011)
instname
Dipòsit Digital de la UB
Universidad de Barcelona
PLoS ONE
Recercat. Dipósit de la Recerca de Catalunya
PLoS ONE, Vol 6, Iss 3, p e16953 (2011)
This is an open-access article distributed under the terms of the Creative Commons Attribution License.-- et al.
[Background]: Probiotics appear to be beneficial in inflammatory bowel disease, but their mechanism of action is incompletely unders
[Background]: Probiotics appear to be beneficial in inflammatory bowel disease, but their mechanism of action is incompletely unders
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d40a103449245c0e0995c26a7c63dc4
http://hdl.handle.net/2445/43606
http://hdl.handle.net/2445/43606