Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Laura Liscum"'
Publikováno v:
Journal of Lipid Research, Vol 51, Iss 8, Pp 2372-2383 (2010)
Loss of function of Niemann-Pick C1 (NPC1) leads to lysosomal free cholesterol storage, resulting in the neurodegenerative disease Niemann-Pick disease type C (NPC). Significant numbers of patients with NPC also suffer from liver disease. Currently,
Externí odkaz:
https://doaj.org/article/67207da1eece42828bade1a7a1302876
Publikováno v:
Journal of Lipid Research, Vol 50, Iss 2, Pp 327-333 (2009)
Niemann-Pick type C (NPC) is a fatal autosomal recessive lysosomal storage disease clinically characterized by neurodegeneration and liver disease. Heterogeneous mutations in the NPC1 and NPC2 genes cause impaired egress of free cholesterol from lyso
Externí odkaz:
https://doaj.org/article/7891ee3b33ff4e238666e302e7683440
Publikováno v:
Journal of Lipid Research, Vol 44, Iss 1, Pp 182-192 (2003)
Plasmalogens are a major sub-class of ethanolamine and choline phospholipids in which the sn-1 position has a long chain fatty alcohol attached through a vinyl ether bond. These phospholipids are proposed to play a role in membrane fusion-mediated ev
Externí odkaz:
https://doaj.org/article/895bc851a469492b8b1d86419f72eb51
Publikováno v:
Journal of Lipid Research, Vol 43, Iss 10, Pp 1708-1717 (2002)
Niemann-Pick C (NPC) is an autosomal recessive lysosomal lipid storage disease characterized by progressive central nervous system degeneration. In cultured human NPC fibroblasts, LDL-derived cholesterol accumulates in lysosomes and endosomes, LDL-ch
Externí odkaz:
https://doaj.org/article/fb991ee0abf14f9d8b66e90137c45a0b
Autor:
Melanie Vincent, Naomi L Sayre, Mark J Graham, Rosanne M Crooke, David J Shealy, Laura Liscum
Publikováno v:
PLoS ONE, Vol 5, Iss 9, p e12941 (2010)
Niemann-Pick type C (NPC) disease is a lysosomal storage disease characterized by the accumulation of cholesterol and glycosphingolipids. The majority of NPC patients die in their teen years due to progressive neurodegeneration; however, half of NPC
Externí odkaz:
https://doaj.org/article/5a268db0d5ab4baea643bd72f55fdf0a
Publikováno v:
Biochim Biophys Acta Mol Cell Res
KIF13B, a kinesin-3 family motor, was originally identified as GAKIN due to its biochemical interaction with human homolog of Drosophila discs-large tumor suppressor (hDLG1). Unlike its homolog KIF13A, KIF13B contains a carboxyl-terminal CAP-Gly doma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1df593b4144694786ece17e345a73d38
https://europepmc.org/articles/PMC6851494/
https://europepmc.org/articles/PMC6851494/
Publikováno v:
The FASEB Journal. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af5dfb991687fbce142681265dab8f8f
https://doi.org/10.1096/fasebj.2018.32.1_supplement.652.15
https://doi.org/10.1096/fasebj.2018.32.1_supplement.652.15
Publikováno v:
Circulation Research. 121
The biomedical research enterprise depends on the fair and objective peer review of research grants, leading to the distribution of resources through efficient and robust competitive methods. In the United States, federal funding agencies and foundat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::428aca42ba34e3ccfb233bc14195ffe3
https://doi.org/10.1161/res.0000000000000158
https://doi.org/10.1161/res.0000000000000158
Autor:
Jean D. Sipe, Lawrence G. Pessolano, Phillip J. Stone, Stephanie E. Seidl, Celeste B. Rich, Laura Liscum, Christopher P. Sullivan, Barbara M. Schreiber
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 32:2741-2750
Objective— Intracellular cholesterol distribution impacts cell function; however, processes influencing endogenous cholesterol trafficking remain largely unknown. Atherosclerosis is associated with vascular inflammation and these studies address th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70280056130d108523d56aa353054621
https://doi.org/10.1161/atvbaha.112.300243
https://doi.org/10.1161/atvbaha.112.300243
Publikováno v:
Journal of Lipid Research, Vol 51, Iss 8, Pp 2372-2383 (2010)
Loss of function of Niemann-Pick C1 (NPC1) leads to lysosomal free cholesterol storage, resulting in the neurodegenerative disease Niemann-Pick disease type C (NPC). Significant numbers of patients with NPC also suffer from liver disease. Currently,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9b8c194ab3c8b2105c1962dc6ffc9f9
http://www.sciencedirect.com/science/article/pii/S0022227520370735
http://www.sciencedirect.com/science/article/pii/S0022227520370735