A Contemporary Review of Immune Checkpoint Inhibitors in Advanced Clear Cell Renal Cell Carcinoma

Autor: Eun-mi Yu, Laura Linville, Matthew Rosenthal, Jeanny B. Aragon-Ching

Publikováno v: Vaccines, Vol 9, Iss 8, p 919 (2021)

The use of checkpoint inhibitors in advanced and metastatic renal cell carcinomas (RCCs) has rapidly evolved over the past several years. While immune-oncology (IO) drug therapy has been successful at resulting in improved responses and survival, com

Externí odkaz: https://doaj.org/article/275ac4d4054c481097ae88e2bdf13b9b

Supplementary Figures 1 and 2 from Relationship of Terminal Duct Lobular Unit Involution of the Breast with Area and Volume Mammographic Densities

Autor: Mark E. Sherman, Louise A. Brinton, Stephen M. Hewitt, Brian L. Sprague, Hisani N. Horne, Hannah Oh, Jackie Xiang, Maya Palakal, Amir Pasha Mahmoudzadeh, Bo Fan, Donald L. Weaver, Pamela M. Vacek, Serghei Malkov, Jeff Wang, John A. Shepherd, Sally D. Herschorn, Rachael E. Chicoine, Jason M. Johnson, Daphne Papathomas, Laura Linville, Jonine D. Figueroa, Ruth M. Pfeiffer, Deesha A. Patel, Gretchen L. Gierach

Supplementary Figure 1. Average Percent Dense Area by Age Supplementary Figure 2. Average Percent Dense Volume by Age.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5228b7cdd55a7d5f0e22be8ab8f034d6
https://doi.org/10.1158/1940-6207.22533634.v1

The effect of anticoagulation on clinical outcomes in novel Coronavirus (COVID-19) pneumonia in a U.S. cohort

Autor: Ghazzal Kango, Shant Ayanian, Sneha Shah, Laura Linville, Karolyn Teufel, Lei Lynn, Arjun Panda, Katrina Hawkins, Juan A. Reyes, Walla Aldhahri

Publikováno v: Thrombosis Research

Background COVID-19 infection is associated with D-dimer elevations, high rates of thrombus formation, and poor clinical outcomes. We sought to determine if empiric therapeutic anticoagulation (AC) affected survival in COVID-19 patients compared to s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d584bbd8589520ae2123de2dc650b7a4
https://doi.org/10.1016/j.thromres.2020.10.031

Polygenic risk score for the prediction of breast cancer is related to lesser terminal duct lobular unit involution of the breast

Autor: Louise A. Brinton, Donald L. Weaver, Deesha A. Patel, Brian L. Sprague, Carolyn Mies, Gretchen L. Gierach, Stephen M. Hewitt, Hannah Oh, Susan E. Clare, Joshua N. Sampson, Pamela M. Vacek, Shaoqi Fan, Daphne Papathomas, Stephen J. Chanock, Montserrat Garcia-Closas, Anna Maria Storniolo, Clara Bodelon, Jackie Xiang, Jonine D. Figueroa, Daniel W. Visscher, Chunyan He, Maya Palakal, Andriy Derkach, Laura Linville

Publikováno v: Bodelon, C, Oh, H, Derkach, A, Sampson, J N, Sprague, B L, Vacek, P, Weaver, D L, Fan, S, Palakal, M, Papathomas, D, Xiang, J, Patel, D A, Linville, L, Clare, S E, Visscher, D W, Mies, C, Hewitt, S M, Brinton, L A, Storniolo, A M V, He, C, Chanock, S J, Garcia-Closas, M, Gierach, G L & Figueroa, J D 2020, ' Polygenic risk score for the prediction of breast cancer is related to lesser terminal duct lobular unit involution of the breast ', NPJ Breast Cancer, vol. 6, pp. 41 . https://doi.org/10.1038/s41523-020-00184-7
npj Breast Cancer, Vol 6, Iss 1, Pp 1-6 (2020)
NPJ Breast Cancer

Terminal duct lobular units (TDLUs) are the predominant anatomical structures where breast cancers originate. Having lesser degrees of age-related TDLU involution, measured as higher TDLUs counts or more epithelial TDLU substructures (acini), is rela

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d470db76ca55339ca846971d195c9e4
https://hdl.handle.net/20.500.11820/cc9b1d92-1613-40bd-8a71-073d4bf762b8

Association between breast cancer genetic susceptibility variants and terminal duct lobular unit involution of the breast

Autor: Gretchen L. Gierach, Nilanjan Chatterjee, Louise A. Brinton, Zeina G. Khodr, Stephen M. Hewitt, Daniel W. Visscher, Jonine D. Figueroa, Berta M. Geller, Stephen J. Chanock, Ruth M. Pfeiffer, Maya Palakal, Donald L. Weaver, Chunyan He, Daphne Papathomas, Clara Bodelon, Hannah Oh, Deesha A. Patel, Mark E. Sherman, Susan E. Clare, Rachael E. Chicoine, Pamela M. Vacek, Carolyn Mies, Montserrat Garcia-Closas, Jackie Xiang, Anna Maria Storniolo, Laura Linville

Publikováno v: International Journal of Cancer. 140:825-832

Terminal duct lobular units (TDLUs) are the predominant source of future breast cancers, and lack of TDLU involution (higher TDLU counts, higher acini count per TDLU and the product of the two) is a breast cancer risk factor. Numerous breast cancer s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c7a67995aedf5dd5d949daa9eec3fc8a
https://doi.org/10.1002/ijc.30512