Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Laura Lintault"'
Autor:
Theresa Casey, Elzbieta I. Zakrzewska, Rhonda L. Maple, Laura Lintault, Charles E. Wade, Lisa A. Baer, April E. Ronca, Karen Plaut
Publikováno v:
Biology Open, Vol 1, Iss 6, Pp 570-581 (2012)
Summary Altered gravity load induced by spaceflight (microgravity) and centrifugation (hypergravity) is associated with changes in circadian, metabolic, and reproductive systems. Exposure to 2-g hypergravity (HG) during pregnancy and lactation decrea
Externí odkaz:
https://doaj.org/article/73a4c1f6cbbe4530983a9ae91caf6f1d
Autor:
Benedikt Bosbach, Michael R. Speicher, Helene Benveniste, Joy Nakitandwe, Jing Ma, James R. Downing, Martina Auer, Claudio Scuoppo, Iris Appelmann, Gang Wu, Scott W. Lowe, Cornelius Miething, James W. Hicks, Prem K. Premsrirut, Laura Lintault, Julie Teruya-Feldstein
Publikováno v:
Nature
PTEN encodes a lipid phosphatase that is underexpressed in many cancers owing to deletions, mutations or gene silencing. PTEN dephosphorylates phosphatidylinositol (3,4,5)-triphosphate, thereby opposing the activity of class I phosphatidylinositol 3-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f4d1ce6bc6a5a74de10fd99d37b7080
https://doi.org/10.1038/nature13239
https://doi.org/10.1038/nature13239
Autor:
Phillip A. Sharp, Alexander Meissner, Amanda G. Young, Stefan J. Erkeland, Roderick T. Bronson, Andrea Ventura, Laura Lintault, Jamie J. Newman, Monte M. Winslow, Tyler Jacks, James R. Stone, Rudolf Jaenisch, Denise Crowley
Publikováno v:
Cell. 132(5):875-886
SummarymiR-17∼92, miR-106b∼25, and miR-106a∼363 belong to a family of highly conserved miRNA clusters. Amplification and overexpression of miR-17∼92 is observed in human cancers, and its oncogenic properties have been confirmed in a mouse mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::137fe49f87fbbb1f1351766ec0ab06da
Autor:
April E. Ronca, Rhonda L. Maple, Theresa Casey, Charles E. Wade, Karen Plaut, Elzbieta I. Zakrzewska, Laura Lintault, Lisa A. Baer
Publikováno v:
Journal of Applied Physiology. 102:2186-2193
Exposure of rat dams to hypergravity during pregnancy is associated with increased pup mortality, reduced food intake, and decreased rates of glucose oxidation and lipogenesis in mammary tissue. We hypothesized that increased pup mortality is due to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3d4749ca44d344965bdcd9d47ab5536
https://doi.org/10.1152/japplphysiol.01015.2006
https://doi.org/10.1152/japplphysiol.01015.2006
Autor:
Kevin Shannon, Scott W. Lowe, Johannes Zuber, Zhen Zhao, Scott C. Kogan, Laura Lintault, Ernesto Diaz-Flores
The p53 tumor suppressor limits proliferation in response to cellular stress through several mechanisms. Here, we test whether the recently described ability of p53 to limit stem cell self-renewal suppresses tumorigenesis in acute myeloid leukemia (A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bd6816e961dae483d1ce76b4a83a457
https://europepmc.org/articles/PMC2895198/
https://europepmc.org/articles/PMC2895198/
Molecular signatures suggest a major role for stromal cells in development of invasive breast cancer
Autor:
Jeffrey P. Bond, T. C. Hunter, Karen Plaut, Donald L. Weaver, Laura Lintault, Seth P. Harlow, Jeffrey H. White, Theresa Casey, Jonathan D. Eneman, Osman V. Patel, Abigail Crocker, Scott Tighe, Joseph Tessitore, Mary A. Stanley, Hyman B. Muss
Publikováno v:
Breast cancer research and treatment. 114(1)
Background Breast cancer invasion and metastasis involves both epithelial and stromal changes. Our objective was to delineate the pivotal role stroma plays in invasion by comparing transcriptomes among stromal and epithelial cells in normal tissue an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::054fe08c034f30677800711873990c8f
https://pubmed.ncbi.nlm.nih.gov/18373191
https://pubmed.ncbi.nlm.nih.gov/18373191
Autor:
David A. Tuveson, Laura Lintault, David G. Kirsch, Margaret McLaughlin, Jan Grimm, Jamie J. Newman, Ralph Weissleder, Elizabeth E. Reczek, Tyler Jacks, Andrea Ventura
Publikováno v:
Nature. 445(7128)
The p53 tumour suppressor is either mutated or inactivated by other alterations in most human cancers. Two papers in this issue show that even brief reactivation of the endogenous p53 genes in established tumours can cause cancer regression in some a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b49e04171a52a6eb50865e09bab38c7f
https://pubmed.ncbi.nlm.nih.gov/17251931
https://pubmed.ncbi.nlm.nih.gov/17251931