Estimation of glucose rate of appearance in portal vein circulation using a phenomenological-based model.

Autor: Laura Lema-Perez, Alejandro Herrón-Bedoya, Valentina Paredes-Ángel, Andrea Hernández-Arango, Carlos E Builes-Montaño, Hernan Alvarez

Publikováno v: PLoS ONE, Vol 18, Iss 5, p e0285849 (2023)

The joint work of the stomach and the small intestine plays a fundamental role in human digestion. In the stomach, food is turned into a semi-fluid mixture that is slowly released into the small intestine, where most enzymatic reactions occur, and nu

Externí odkaz: https://doaj.org/article/1627db600d8648e1af23c948098c2a0e

Carbohydrate Count Aided by a Simulation of Postprandial Glucose Dynamics Generated by a Mathematical Model in People with Type 1 Diabetes Mellitus. A Study Protocol for a Clinical Trial

Autor: Carlos Esteban Builes-Montaño, Laura Lema-Perez, Juan Carlos Restrepo, Jose F. Garcia-Tirado, Hernan Alvarez, Alex Ramirez-Rincón, John J. Zuleta

Publikováno v: SSRN Electronic Journal.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4fb56c8f0f4204598ac31f7b778c5e39
https://doi.org/10.2139/ssrn.4223440

The Sugars with the Potential to Prolong Human Life

Autor: Hideya Shintani, Laura Lema-Perez, Tomoya Shintani

Sugar is the main source of energy for all cells in the human body. On the other hand, cells can also obtain energy from fats and proteins depending on conditions, although this metabolic process is more difficult and less common in cells. Sugar inta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91f0f7c6284ac62a09d3081e5579d42c
https://doi.org/10.5772/intechopen.97885

Main glucose hepatic fluxes in healthy subjects predicted from a phenomenological-based model

Autor: Carlos E. Builes-Montaño, Laura Lema-Perez, Jose Garcia-Tirado, Hernan Alvarez

Publikováno v: Computers in Biology and Medicine

The liver has a unique role in blood glucose regulation in postprandial, postabsorptive, and fasting states. In the context of diabetes technology, current maximal models of glucose homeostasis lack a proper dynamical description of main glucose-rela

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::056342abeb5cbe83768a2ea27676150e
https://doi.org/10.1016/j.compbiomed.2022.105232

On parameter interpretability of phenomenological-based semiphysical models in biology

Autor: Hernan Alvarez, Laura Lema-Perez, Rafael Muñoz-Tamayo, Jose Garcia-Tirado

Publikováno v: Informatics in Medicine Unlocked
Informatics in Medicine Unlocked, 2019, 15, pp.100158. ⟨10.1016/j.imu.2019.02.002⟩
Informatics in Medicine Unlocked, Vol 15, Iss, Pp-(2019)
Informatics in Medicine Unlocked (15), 100158. (2019)

Empirical and phenomenological-based models are used to represent biological and physiological processes. Phenomenological models are derived from the knowledge of the mechanisms that underlie the behavior of the system under study, while empirical m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::231ce610b18510c7b10dbe8afd856b07
https://hal.archives-ouvertes.fr/hal-02192507/file/2019_Lema.pdf