Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Laura Lafon"'
Autor:
Jimena Hochmann, Magdalena Millán, Paola Hernández, Laura Lafon, Natali D’Aiuto, Vanesa Pereira, Felipe Martins, Estefanía Sicco, José Sotelo Silveira, Ronell Bologna Molina, Miguel Arocena
Publikováno v:
Odontoestomatología, Vol 25 (2024)
Objetivos. En este estudio se evaluarán los niveles de estrés oxidativo, y daño en el ADN en un modelo celular de carcinogénesis oral temprano, sometido a un microambiente hipóxico. Métodos. Utilizamos queratinocitos humanos (HaCaT) transducido
Externí odkaz:
https://doaj.org/article/341865f882dd4fd7b29f4798e05526fa
Autor:
Jimena Hochmann, Magdalena Millán, Paola Hernández, Laura Lafon-Hughes, Natali D’ Aiuto, Alejandro Silva, Juan Llaguno, Julia Alonso, Ariel Fernández, Vanesa Pereira-Prado, José Sotelo-Silveira, Ronell Bologna-Molina, Miguel Arocena
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Infection with high-risk human papillomaviruses like HPV-16 and HPV-18 is highly associated with the development of cervical and other cancers. Malignant transformation requires viral oncoproteins E5, E6 and E7, which promote cell proliferat
Externí odkaz:
https://doaj.org/article/51e257cc6e2c4dfd9d24b10e29e126bc
Autor:
Laura Lafon-Hughes
Publikováno v:
Pathogens, Vol 12, Iss 6, p 806 (2023)
Despite what its name suggests, the effects of the COVID-19 pandemic causative agent “Severe Acute Respiratory Syndrome Coronavirus-2” (SARS-CoV-2) were not always confined, neither temporarily (being long-term rather than acute, referred to as L
Externí odkaz:
https://doaj.org/article/a6681a72303944eca3d26753a8d574af
Autor:
Valentina Perini, Michelle Schacke, Pablo Liddle, Salomé Vilchez-Larrea, Deborah J. Keszenman, Laura Lafon-Hughes
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 21, p 8288 (2020)
Poly(ADP-ribosyl)polymerase (PARP) synthesizes poly(ADP-ribose) (PAR), which is anchored to proteins. PAR facilitates multiprotein complexes’ assembly. Nuclear PAR affects chromatin’s structure and functions, including transcriptional regulation.
Externí odkaz:
https://doaj.org/article/6f618da618d84e7287dc111dd1969cc3
Autor:
Michelle Schacke, Janani Kumar, Nicholas Colwell, Kole Hermanson, Gustavo A. Folle, Sergei Nechaev, Archana Dhasarathy, Laura Lafon-Hughes
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 3, p 518 (2019)
Poly- adenosine diphosphate (ADP)-ribose (PAR) is a polymer synthesized as a posttranslational modification by some poly (ADP-ribose) polymerases (PARPs), namely PARP-1, PARP-2, tankyrase-1, and tankyrase-2 (TNKS-1/2). PARP-1 is nuclear and has also
Externí odkaz:
https://doaj.org/article/5fa5418433c244debfb6d68da19bc357
Publikováno v:
PeerJ, Vol 2, p e617 (2014)
Poly-ADP-ribose (PAR) is a polymer of up to 400 ADP-ribose units synthesized by poly-ADP-ribose-polymerases (PARPs) and degraded by poly-ADP-ribose-glycohydrolase (PARG). Nuclear PAR modulates chromatin compaction, affecting nuclear functions (gene e
Externí odkaz:
https://doaj.org/article/463205f743084d8e8c6ee352b0da3109
Autor:
LAURA LAFON HUGHES
Publikováno v:
BIOCELL. 46:2531-2535
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4471eacd8cbac16648dd6e8edd152c99
https://doi.org/10.32604/biocell.2022.022713
https://doi.org/10.32604/biocell.2022.022713
Publikováno v:
Parasitology. 148:1680-1690
Chagas disease is a potentially life-threatening protozoan infection affecting around 8 million people, for which only chemotherapies with limited efficacy and severe adverse secondary effects are available. The aetiological agent, Trypanosoma cruzi,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4bd802b6cf2b665247c9ee74c95d952e
https://doi.org/10.1017/s0031182021001402
https://doi.org/10.1017/s0031182021001402
Publikováno v:
Parasitology. 148(13)
Chagas disease is a potentially life-threatening protozoan infection affecting around 8 million people, for which only chemotherapies with limited efficacy and severe adverse secondary effects are available. The aetiological agent, Trypanosoma cruzi,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3bf728fca8cd8bd9e7f7a05f18093e20
https://pubmed.ncbi.nlm.nih.gov/35060470
https://pubmed.ncbi.nlm.nih.gov/35060470
Autor:
LAURA LAFON HUGHES
UNSTRUCTURED This is a peer review report.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ee261ae9840d5e0ee93c44038228e67
https://doi.org/10.2196/preprints.28722
https://doi.org/10.2196/preprints.28722
