The distinct fate of smooth and rough Mycobacterium abscessus variants inside macrophages

Autor: Anne-Laure Roux, Albertus Viljoen, Aïcha Bah, Roxane Simeone, Audrey Bernut, Laura Laencina, Therese Deramaudt, Martin Rottman, Jean-Louis Gaillard, Laleh Majlessi, Roland Brosch, Fabienne Girard-Misguich, Isabelle Vergne, Chantal de Chastellier, Laurent Kremer, Jean-Louis Herrmann

Publikováno v: Open Biology, Vol 6, Iss 11 (2016)

Mycobacterium abscessus is a pathogenic, rapidly growing mycobacterium responsible for pulmonary and cutaneous infections in immunocompetent patients and in patients with Mendelian disorders, such as cystic fibrosis (CF). Mycobacterium abscessus is k

Externí odkaz: https://doaj.org/article/9b76ac6e7a1349e1944d848d81561f14

MmpL8

Autor: Violaine, Dubois, Albertus, Viljoen, Laura, Laencina, Vincent, Le Moigne, Audrey, Bernut, Faustine, Dubar, Mickaël, Blaise, Jean-Louis, Gaillard, Yann, Guérardel, Laurent, Kremer, Jean-Louis, Herrmann, Fabienne, Girard-Misguich

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America. 115(43)

Mycobacterium abscessus is a peculiar rapid-growing Mycobacterium (RGM) capable of surviving within eukaryotic cells thanks to an arsenal of virulence genes also found in slow-growing mycobacteria (SGM), such as Mycobacterium tuberculosis. A screen b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7ec05007d839baa98690f02b79d9732d
https://pubmed.ncbi.nlm.nih.gov/30301802

Identification of genes required for Mycobacterium abscessus growth in vivo with a prominent role of the ESX-4 locus

Autor: Vincent Le Moigne, Jean Louis Gaillard, Anne Laure Roux, Bérengère Lombard, Albertus Viljoen, Jean-Louis Herrmann, Eric J. Rubin, Damarys Loew, Audrey Bernut, Laurent Kremer, Laura Piel, Fabienne Girard-Misguich, Justin R. Pritchard, Laleh Majlessi, Roland Brosch, Laura Laencina, Violaine Dubois

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2018, 115 (5), pp.E1002-E1011. ⟨10.1073/pnas.1713195115⟩
Proceedings of the National Academy of Sciences of the United States of America, 2018, 115 (5), pp.E1002-E1011. ⟨10.1073/pnas.1713195115⟩

International audience; Mycobacterium abscessus, a rapidly growing mycobacterium (RGM) and an opportunistic human pathogen, is responsible for a wide spectrum of clinical manifestations ranging from pulmonary to skin and soft tissue infections. This

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4b18c07c802fc5a28d1e889d985c831
https://hal-pasteur.archives-ouvertes.fr/pasteur-02046027

Mycobacterium abscessus Phospholipase C Expression Is Induced during Coculture within Amoebae and Enhances M. abscessus Virulence in Mice

Autor: Jean-Louis Herrmann, Isabelle Poncin, Vincent Le Moigne, Carole Serveau-Avesque, Laura Laencina, Nathalie Soismier, Stéphane Canaan, Roland Brosch, Martin Rottman, Gilles Etienne, Fabienne Girard-Misguich, Jean-Louis Gaillard, Anne-Laure Roux, Fabien Le Chevalier, Jean Claude Bakala N'Goma

Publikováno v: Infection and Immunity
Infection and Immunity, American Society for Microbiology, 2015, 83 (2), pp.780-791. ⟨10.1128/IAI.02032-14⟩
Infection and Immunity, 2015, 83 (2), pp.780-791. ⟨10.1128/IAI.02032-14⟩
Infection and Immunity, 2015, 83, pp.780-791. ⟨10.1128/iai.02032-14⟩

Mycobacterium abscessus is a pathogenic, rapidly growing mycobacterium involved in pulmonary and cutaneo-mucous infections worldwide, to which cystic fibrosis patients are exquisitely susceptible. The analysis of the genome sequence of M. abscessus s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e5f6871343a887bcb7e76cf87d678a3
https://doi.org/10.1128/iai.02032-14