Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Laura L. Stunz"'
Autor:
Kai J. Rogers, Paige T. Richards, Zeb R. Zacharias, Laura L. Stunz, Rahul Vijay, Noah S. Butler, Kevin L. Legge, Gail A. Bishop, Wendy Maury
Publikováno v:
Viruses, Vol 15, Iss 6, p 1353 (2023)
Macrophages are critical in the pathogenesis of a diverse group of viral pathogens, both as targets of infection and for eliciting primary defense mechanisms. Our prior in vitro work identified that CD40 signaling in murine peritoneal macrophages pro
Externí odkaz:
https://doaj.org/article/8c6c1dee7bbf437da582233b4cccd168
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Abstract TRAF3 is a versatile intracellular adapter protein with multiple context-specific roles. Uniquely in B cells, TRAF3 deficiency enhances survival and increases the risk of transformation, as loss of TRAF3 is observed in several types of B cel
Externí odkaz:
https://doaj.org/article/cabe35fe3e8245a3acd52f3226bbe784
Autor:
Melissa E. Munroe, Jourdan R. Anderson, Timothy F. Gross, Laura L. Stunz, Gail A. Bishop, Judith A. James
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Systemic lupus erythematosus (SLE) and other autoimmune diseases are propelled by immune dysregulation and pathogenic, disease-specific autoantibodies. Autoimmunity against the lupus autoantigen Sm is associated with cross-reactivity to Epstein-Barr
Externí odkaz:
https://doaj.org/article/cb3059a19d6b475fabedff1c96a36911
Autor:
Pradeep Bangalore-Prakash, Laura L. Stunz, Nurbek Mambetsariev, Amy L. Whillock, Bruce S. Hostager, Gail A. Bishop
Publikováno v:
Blood Advances, Vol 1, Iss 27, Pp 2712-2723 (2017)
Abstract: Loss-of-function mutations in genes encoding the signaling protein tumor necrosis factor receptor–associated factor 3 (TRAF3) are commonly found in human B-cell malignancies, especially multiple myeloma and B-cell lymphoma (BCL). B-cell T
Externí odkaz:
https://doaj.org/article/ce06e39817a1450491b72d3d2d7ba5a1
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
The adaptor protein TNF receptor-associated factor 3 (TRAF3) serves as a powerful negative regulator in multiple aspects of B cell biology. Early in vitro studies in transformed cell lines suggested the potential of TRAF3 to inhibit signaling by its
Externí odkaz:
https://doaj.org/article/c3b50a46ee4f43a39f51821c03fa9f64
Autor:
Maury, Kai J. Rogers, Paige T. Richards, Zeb R. Zacharias, Laura L. Stunz, Rahul Vijay, Noah S. Butler, Kevin L. Legge, Gail A. Bishop, Wendy
Publikováno v:
Viruses; Volume 15; Issue 6; Pages: 1353
Macrophages are critical in the pathogenesis of a diverse group of viral pathogens, both as targets of infection and for eliciting primary defense mechanisms. Our prior in vitro work identified that CD40 signaling in murine peritoneal macrophages pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::a4e854e679d890d5864dc13bdb248db1
Autor:
Emma L. Hornick, Laura L. Stunz, Shakoora Sabree, Xiaosheng Wu, Thomas E. Witzig, Gail A. Bishop
Publikováno v:
Cancers; Volume 14; Issue 20; Pages: 5029
TNF receptor-associated factor 3 (TRAF3) is an adapter protein that inhibits many signals that promote B cell survival and activation. Mice with a B cell-specific TRAF3 deficiency and humans with a rare haploinsufficiency in TRAF3 have enhanced devel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::209a8de1e06a6f41dbde63034baf9f5a
https://doi.org/10.3390/cancers14205029
https://doi.org/10.3390/cancers14205029
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Scientific Reports
TRAF3 is a versatile intracellular adapter protein with multiple context-specific roles. Uniquely in B cells, TRAF3 deficiency enhances survival and increases the risk of transformation, as loss of TRAF3 is observed in several types of B cell cancers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8396945d9d525e691c93c3d4605cd477
https://doaj.org/article/cabe35fe3e8245a3acd52f3226bbe784
https://doaj.org/article/cabe35fe3e8245a3acd52f3226bbe784
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e102120 (2014)
Our laboratory reported previously that TNF receptor associated factor 3 (TRAF3) is a positive regulator of TCR signaling and T cell function. In the current study, we present new findings that reveal differential roles for TRAF3 in the regulation of
Externí odkaz:
https://doaj.org/article/2eddca4e565140b188a572c2d566a90b
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-1 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-1 (2019)
TRAF3 is a versatile intracellular adapter protein with multiple context-specific roles. Uniquely in B cells, TRAF3 deficiency enhances survival and increases the risk of transformation, as loss of TRAF3 is observed in several types of B cell cancers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::434c45d006fe10b599f1d1089f1390bc
http://europepmc.org/articles/PMC6864106
http://europepmc.org/articles/PMC6864106