Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Laura L. Richardson"'
Autor:
Aaron M. Dom, Laura L. Richardson, Alison R. Williams, Maria A. Serrat, Morgan L. Efaw, James T. Buchanan
Publikováno v:
Anatomical Sciences Education. 7:406-416
Didactic lessons are only one part of the multimodal teaching strategies used in gross anatomy courses today. Increased emphasis is placed on providing more opportunities for students to develop lifelong learning and critical thinking skills during m
Publikováno v:
Biochemical and Biophysical Research Communications. 340:8-12
Mammalian spermatogenesis is precisely regulated by many germ cell-specific factors. In search for such a germ cell-specific factor, we have identified a novel mouse gene testis-specific factor 1 (TESF-1). Messenger RNA of TESF-1 was found only in th
Publikováno v:
Molecular Reproduction and Development. 73:1284-1291
The Niemann-Pick C1 (NPC1) gene encodes for a multiple membrane spanning protein, which regulates the trafficking of low-density lipoprotein-mediated endocytosed cholesterol. Mutation of the human NPC1 gene causes Niemann-Pick type C (NPC) disease. T
Publikováno v:
Molecular and Cellular Biology. 24:1655-1666
We devised a sensitive method for the site-specific detection of rare meiotic DNA strand breaks in germ cell-enriched testicular cell populations from mice that possess or lack an active recombination hot spot at the H2-Ea gene. Using germ cells from
Autor:
Luciano Debeljuk, Laura L. Richardson, Katrina G. Waymire, Patryce L. Mahar, Jeff Warren, Lonnie D. Russell, Andrea J. Ross, Scott P. Amy, Grant R. MacGregor
Publikováno v:
Biology of Reproduction. 65:318-332
Bclw is a death-protecting member of the Bcl2 family of apoptosis-regulating proteins. Mice that are mutant for Bclw display progressive and nearly complete testicular degeneration. We performed a morphometric evaluation of testicular histopathology
Publikováno v:
Biology of Reproduction. 62:789-796
Meiotic recombination during gametogenesis is critical for proper chromosome segregation. However, the participating proteins and mechanics of recombination are not well understood in mammals. DNA repair enzymes play an essential role in both mitosis
Characterization of the Mouse Xpf DNA Repair Gene and Differential Expression during Spermatogenesis
Autor:
Lisa Stubbs, Sandra L. McCutchen-Maloney, Mary Ann Handel, Laura L. Richardson, Mark Shannon, Mona H. Hwang, Jane Lamerdin, Michael P. Thelen
Publikováno v:
Genomics. 62:427-435
The human XPF protein, an endonuclease subunit essential for DNA excision repair, may also function in homologous recombination. To investigate a possible link between mammalian XPF and recombination that occurs during meiosis, we isolated, character
Publikováno v:
FEBS Letters. 462:329-334
As the initiator of DNA double-strand breaks during meiosis in Saccharomyces cerevisiae, the SPO11 protein is essential for recombination. Similarity between SPO11 and archaebacterial TOP6A proteins points to evolutionary specialization of a DNA clea
Autor:
Maria A, Serrat, Aaron M, Dom, James T, Buchanan, Alison R, Williams, Morgan L, Efaw, Laura L, Richardson
Publikováno v:
Anatomical sciences education. 7(5)
Didactic lessons are only one part of the multimodal teaching strategies used in gross anatomy courses today. Increased emphasis is placed on providing more opportunities for students to develop lifelong learning and critical thinking skills during m
Publikováno v:
Biology of Reproduction. 52:320-330
Both Sertoli and myoid cells have been shown to be required for the appropriate deposition of basement membrane in the testis. We sought to define the pattern of basement membrane gene expression in Sertoli and peritubular myoid cells in vitro in ord