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pro vyhledávání: '"Laura L. Fleischer"'
Autor:
Ling Li, Robert Conradi, Wen-Song Yue, Bella Osak, Smith Yvonne Dorothy, Jie Jack Li, Danielle Dettling, Satya Reddy, Veerabahu Shanmugasundaram, Manju Swaroop, Zenquan Wang, Laura L. Fleischer, Christy Xiaodong Ji, William Glen Harter, Laura Fitzgerald
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 20:4932-4935
A series of aminomethylpyrazoles were prepared and evaluated using cell-based Smoothened β-lactamase reporter assay and Smoothened binding assay. Potent Smoothened antagonists 10k and 10l were found to inhibit hair growth in vivo in the C3H/HeN mous