Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Laura L. Etchells"'
Autor:
Richard A. Bryce, Carlos Kremer, Sally Freeman, Laura L. Etchells, Nicolás Veiga, David Mansell, Julia Torres
Publikováno v:
Tetrahedron. 66:8949-8957
myo -Inositol 1,2,3-trisphosphate [Ins(1,2,3)P 3 ], a component in mammalian cells, possesses the correct chemical properties of an intracellular iron transit ligand. Here we have examined the conformation of the Ins(1,2,3)P 3 –Fe 3+ complex. The s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a2427862bc66bd0a30a2bb3eddf27bc
https://doi.org/10.1016/j.tet.2010.09.033
https://doi.org/10.1016/j.tet.2010.09.033
Publikováno v:
ResearcherID
We report the first use of exciplex-based split-probes for detection of the wild type and *3 mutant alleles of human cytochrome P450 2C9. A tandem 8-mer split DNA oligonucleotide probe system was designed that allows detection of the complementary ta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c9615e2edd85d8de0223f077f94fe38
https://doi.org/10.1080/07391102.2008.10507209
https://doi.org/10.1080/07391102.2008.10507209
Publikováno v:
Tetrahedron. 62:10914-10927
The pyrrolidine natural products, plakoridines A and B, as well as an array of unnatural analogues, have been prepared using a five-step synthetic sequence modelled on a biogenetic theory. The key transformation involves a ‘Mannich/Michael/internal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49e4b5fec73434fb61f71d22dd726914
https://doi.org/10.1016/j.tet.2006.08.075
https://doi.org/10.1016/j.tet.2006.08.075
Publikováno v:
Tetrahedron Letters. 46:2803-2807
An expedient synthetic route to the fully substituted pyrrolidine ring system of the plakoridines is described using an approach modeled on a plausible biosynthetic pathway.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ff0a098d954227f4908cf541e070be9
https://doi.org/10.1016/j.tetlet.2005.02.124
https://doi.org/10.1016/j.tetlet.2005.02.124
Publikováno v:
ChemCatChem. 4:1259-1261
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a3b9fe9f0ec1c95c3dd8bcd29a6db06
https://doi.org/10.1002/cctc.201200202
https://doi.org/10.1002/cctc.201200202
Autor:
Ali Reza Sardarian, A Gulati, S Hawisa, Elena V. Bichenkova, Laura L. Etchells, A Gbaj, L Walsh, Kenneth T. Douglas, Savage He
Publikováno v:
Libyan Journal of Medicine, Vol 4, Iss 4, p 090801 (2009)
Libyan Journal of Medicine; Vol 4, No 4 (2009)
The Libyan Journal of Medicine
Libyan Journal of Medicine; Vol 4, No 4 (2009); 152-159
Libyan Journal of Medicine; Vol 4, No 4 (2009)
The Libyan Journal of Medicine
Libyan Journal of Medicine; Vol 4, No 4 (2009); 152-159
The detection of single base mismatches in DNA is important for diagnostics, treatment of genetic diseases, and identification of single nucleotide polymorphisms. Highly sensitive, specific assays are needed to investigate genetic samples from patien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c908387f42cbac532faec9e947cc3ca4
http://2657.indexcopernicus.com/fulltxt.php?ICID=892300
http://2657.indexcopernicus.com/fulltxt.php?ICID=892300
Autor:
Carlos Kremer, Elena V. Bichenkova, Alexander J. Blake, Laura L. Etchells, Christopher J. Barker, Richard A. Bryce, Alvaro Díaz, Nicholas J. W. Rattray, Sally Freeman, Carl H. Schwalbe, David Mansell
Publikováno v:
Chemical communications (Cambridge, England). (41)
Natural myo-inositol phosphate antioxidants containing the 1,2,3-trisphosphate motif bind Fe(3+) in the unstable penta-axial conformation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eae8666309d0df0e776ed2e7f9b931b
https://pubmed.ncbi.nlm.nih.gov/18956055
https://pubmed.ncbi.nlm.nih.gov/18956055
Autor:
Abdul M Gbaj, Kenneth T. Douglas, Laura L. Etchells, Elena V. Bichenkova, David Whitcombe, L Walsh, Ali Reza Sardarian, Maria Candelaria Rogert
Publikováno v:
Bioscience reports. 28(1)
Scorpion probes, specific DNA probe sequences maintained in a hairpin–loop, can be modified to carry the components of an exciplex for use as a novel fluorescence-based method for specific detection of DNA. The exciplex partners (5′-pyrenyl and 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5b8c23f094431cc4403d8469be12641
https://pubmed.ncbi.nlm.nih.gov/18215149
https://pubmed.ncbi.nlm.nih.gov/18215149
Autor:
Savage He, L Walsh, Abdul M Gbaj, Kenneth T. Douglas, Laura L. Etchells, Ali Sardarian, C Rogert, Elena V. Bichenkova
Publikováno v:
Organicbiomolecular chemistry. 5(7)
This research describes the effects of structural variation and medium effects for the novel split-oligonucleotide (tandem) probe systems for exciplex-based fluorescence detection of DNA. In this approach the detection system is split at a molecular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d83243e444c3345b711f4990dc6682d6
https://pubmed.ncbi.nlm.nih.gov/17377657
https://pubmed.ncbi.nlm.nih.gov/17377657
Autor:
Neil M. Kershaw, Ryoichi Nakamura, Laura L. Etchells, Hazel Ryan, Ryo Takeuchi, Kengo Sakaguchi, Roger C. Whitehead, Jeremy R. Doncaster, Ali Sardarian
Publikováno v:
ChemInform. 37
An array of novel analogues of the marine oxylipins, the manzamenones and plakoridines, have been prepared in divergent fashion using an approach modelled on a biogenetic theory. Many of the target compounds show potent inhibition of DNA polymerases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::265efe14f95bcff2a875e91cc11cdab7
https://doi.org/10.1002/chin.200635236
https://doi.org/10.1002/chin.200635236