Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Laura L Thomas"'
Publikováno v:
Methods Mol Biol
Methods in Molecular Biology ISBN: 9781071626382
Methods in Molecular Biology ISBN: 9781071626382
Rab GTPases are key regulators of membrane trafficking. When GTP-bound, or "active," Rabs are anchored to membranes and recruit effector proteins that mediate vesicle formation, transport, and fusion. Rabs are inactivated by GTPase-activating protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::576a7fdf16867b8dcccbe9155352118b
https://europepmc.org/articles/PMC9851423/
https://europepmc.org/articles/PMC9851423/
Autor:
Katelyn M. Atkins, Laura L. Thomas, Jonathan Barroso-González, Laurel Thomas, Sylvain Auclair, Jun Yin, Hyeog Kang, Jay H. Chung, Jimmy D. Dikeakos, Gary Thomas
Publikováno v:
Cell Reports, Vol 8, Iss 5, Pp 1545-1557 (2014)
SIRT1 regulates the DNA damage response by deacetylating p53, thereby repressing p53 transcriptional output. Here, we demonstrate that the sorting protein PACS-2 regulates SIRT1-mediated deacetylation of p53 to modulate the DNA damage response. PACS-
Externí odkaz:
https://doaj.org/article/77026dbf1a5d4733a008cd6320ee59b9
Publikováno v:
Molecular Biology of the Cell
Rab family GTPases are key organizers of membrane trafficking and function as markers of organelle identity. Accordingly, Rab GTPases often occupy specific membrane domains, and mechanisms exist to prevent the inappropriate mixing of distinct Rab dom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad33e6f1c0fa47adaa89d09e61ded79d
http://europepmc.org/articles/PMC8351538
http://europepmc.org/articles/PMC8351538
Autor:
Laura L. Thomas, J. Christopher Fromme
Publikováno v:
Curr Opin Cell Biol
Virtually all transport events at the Golgi complex are regulated by Arf and Rab family GTPases. Recent work has advanced our knowledge regarding the mechanisms controlling GTPase activity, and it has become clear that GTPases do not act in isolation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ec8d07a5bedb1c3c029d12543fff8c9
https://doi.org/10.1016/j.ceb.2020.01.014
https://doi.org/10.1016/j.ceb.2020.01.014
Publikováno v:
Aquaculture. 508:1-9
Growth of the oyster aquaculture industry on the US east coast has accelerated in recent decades due to advances in breeding technologies and grow-out methods. As the industry grows, competition in the market place is likely to increase attention to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3dd601705aea176fae81f7cdce8e5f4
https://doi.org/10.1016/j.aquaculture.2019.03.061
https://doi.org/10.1016/j.aquaculture.2019.03.061
Autor:
Laura L. Thomas, Zhe Zhuang, Sarah L. Gaffen, Steven R. Little, Cinthia M F Pacheco, Mostafa S. Shehabeldin, Gustavo Pompermaier Garlet, Sayuri Yoshizawa, Konstantinos Verdelis, Charles Sfeir, Katia L M Maltos
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Periodontal disease (PD) is a chronic destructive inflammatory disease of the tooth-supporting structures that leads to tooth loss at its advanced stages. Although the disease is initiated by a complex organization of oral microorganisms in the form
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::104f183461c8e2d0d66ae89e3c168728
Autor:
Greg J Hermann, Emily Scavarda, Allison M Weis, Daniel S Saxton, Laura L Thomas, Rebecca Salesky, Hannah Somhegyi, Thomas P Curtin, Alec Barrett, Olivia K Foster, Annalise Vine, Katherine Erlich, Elizabeth Kwan, Beverley M Rabbitts, Kaila Warren
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43043 (2012)
The human disease Hermansky-Pudlak syndrome results from defective biogenesis of lysosome-related organelles (LROs) and can be caused by mutations in subunits of the BLOC-1 complex. Here we show that C. elegans glo-2 and snpn-1, despite relatively lo
Externí odkaz:
https://doaj.org/article/60d7b6b7cb714b1da186bfbe8d8edcaa
Publikováno v:
The Journal of Cell Biology
The TRAPP complexes are nucleotide exchange factors that activate Rab GTPases, and four different versions of TRAPP have been reported. Thomas et al. show that only two versions of TRAPP are detectable in normal cells and demonstrate that the TRAPPII
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30d317d68e2e6dd4ca255996e65083e1
https://doi.org/10.1083/jcb.201705214
https://doi.org/10.1083/jcb.201705214
Publikováno v:
Developmental cell. 48(1)
Summary Correct localization of Rab GTPases in cells is critical for proper function in membrane trafficking, yet the mechanisms that target Rabs to specific subcellular compartments remain controversial. Guanine nucleotide exchange factors (GEFs) ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c58bbebcce8f7718878e529f393d40ce
https://pubmed.ncbi.nlm.nih.gov/30620905
https://pubmed.ncbi.nlm.nih.gov/30620905
Autor:
J. Christopher Fromme, Laura L. Thomas
Publikováno v:
The Journal of Cell Biology
Rab GTPases control vesicle formation and transport, but which proteins are important for their regulation is incompletely understood. Thomas and Fromme provide definitive evidence that TRAPPII is a GEF for the yeast Rab11 homologues Ypt31/32 and imp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aa3bbb82f94a35d06f595f50b15e28f
https://pubmed.ncbi.nlm.nih.gov/27872253
https://pubmed.ncbi.nlm.nih.gov/27872253