Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Laura L Colgin"'
Autor:
Thomas K Creson, Camilo Rojas, Ernie Hwaun, Thomas Vaissiere, Murat Kilinc, Andres Jimenez-Gomez, Jimmy Lloyd Holder Jr, Jianrong Tang, Laura L Colgin, Courtney A Miller, Gavin Rumbaugh
Publikováno v:
eLife, Vol 8 (2019)
It remains unclear to what extent neurodevelopmental disorder (NDD) risk genes retain functions into adulthood and how they may influence disease phenotypes. SYNGAP1 haploinsufficiency causes a severe NDD defined by autistic traits, cognitive impairm
Externí odkaz:
https://doaj.org/article/10c02d4e26fb45a18f6fa15636bfbc56
Autor:
Juan E. Villacres, Nicholas Riveira, Sohmee Kim, Laura L. Colgin, Jeffrey L. Noebels, Angel Y. Lopez
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract ANK3 is a leading bipolar disorder (BD) candidate gene in humans and provides a unique opportunity for studying epilepsy-BD comorbidity. Previous studies showed that deletion of Ank3-1b, a BD-associated variant of Ank3 in mice leads to incre
Externí odkaz:
https://doaj.org/article/eb0030398d8e4ef48dab1cf80093f0e6
Autor:
Christopher S Rex, Laura L Colgin, Yousheng Jia, Malcolm Casale, Theodore K Yanagihara, Maria Debenedetti, Christine M Gall, Eniko A Kramar, Gary Lynch
Publikováno v:
PLoS ONE, Vol 4, Iss 11, p e7761 (2009)
Sharp waves (SPWs) are irregular waves that originate in field CA3 and spread throughout the hippocampus when animals are alert but immobile or as a component of the sleep EEG. The work described here used rat hippocampal slices to investigate the fa
Externí odkaz:
https://doaj.org/article/9a98ae7d87904d4ca965edacca6cfff3
Autor:
Georgia M. Alexander, Shannon Farris, Jason R. Pirone, Chenguang Zheng, Laura L. Colgin, Serena M. Dudek
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Recent work has implicated hippocampal subfield CA2 in encoding social and contextual memory yet the neural mechanisms are not known. Here, Alexander and colleagues demonstrate that, compared to CA1 neurons, CA2 neurons modify their place fields when
Externí odkaz:
https://doaj.org/article/0bc09f47e5c84251aaeccfdc7b5a8a19
Publikováno v:
The FASEB Journal. 36